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Journal Articles

The Surface composition of asteroid 162173 Ryugu from Hayabusa2 near-infrared spectroscopy

Kitazato, Kohei*; Milliken, R. E.*; Iwata, Takahiro*; Abe, Masanao*; Otake, Makiko*; Matsuura, Shuji*; Arai, Takehiko*; Nakauchi, Yusuke*; Nakamura, Tomoki*; Matsuoka, Moe*; et al.

Science, 364(6437), p.272 - 275, 2019/04

 Times Cited Count:140 Percentile:99.81(Multidisciplinary Sciences)

The near-Earth asteroid 162173 Ryugu, the target of Hayabusa2 sample return mission, is believed to be a primitive carbonaceous object. The Near Infrared Spectrometer (NIRS3) on Hayabusa2 acquired reflectance spectra of Ryugu's surface to provide direct measurements of the surface composition and geological context for the returned samples. A weak, narrow absorption feature centered at 2.72 micron was detected across the entire observed surface, indicating that hydroxyl (OH)-bearing minerals are ubiquitous there. The intensity of the OH feature and low albedo are similar to thermally- and/or shock-metamorphosed carbonaceous chondrite meteorites. There are few variations in the OH-band position, consistent with Ryugu being a compositionally homogeneous rubble-pile object generated from impact fragments of an undifferentiated aqueously altered parent body.

Journal Articles

Rational evaluation of the therapeutic effect and dosimetry of auger electrons for radionuclide therapy in a cell culture model

Shinohara, Ayaka*; Hanaoka, Hirofumi*; Sakashita, Tetsuya*; Sato, Tatsuhiko; Yamaguchi, Aiko*; Ishioka, Noriko*; Tsushima, Yoshito*

Annals of Nuclear Medicine, 32(2), p.114 - 122, 2018/02

 Times Cited Count:6 Percentile:53.26(Radiology, Nuclear Medicine & Medical Imaging)

Radionuclide therapy with low-energy auger electron emitters could potentially provide high anti-tumor efficacy while keeping normal organs toxicity low. In this study, we evaluated the usefulness of auger electron emitter $$^{125}$$I and compared it with beta-emitter $$^{131}$$I for tumor treatment in 2D and 3D cell culture models. The computer simulation model for 2D and 3D cell culture were constructed, and the absorbed radiation dose of $$^{125}$$I or $$^{131}$$I in each model were calculated by using a Monte Carlo simulation code (PHITS). The therapeutic effect of $$^{125}$$I was comparable to that of $$^{131}$$I in 2D model, but the efficacy was inferior to that of $$^{131}$$I-MIBG in 3D model, since crossfire effect is negligible and the homogeneous distribution of radionuclide was insufficient.

Journal Articles

Development of a widely usable amino acid tracer; $$^{76}$$Br-$$alpha$$-methyl-phenylalanine for tumor PET imaging

Hanaoka, Hirofumi*; Ohshima, Yasuhiro; Suzuki, Yurika*; Yamaguchi, Aiko*; Watanabe, Shigeki; Uehara, Tomoya*; Nagamori, Shushi*; Kanai, Yoshikatsu*; Ishioka, Noriko; Tsushima, Yoshito*; et al.

Journal of Nuclear Medicine, 56(5), p.791 - 797, 2015/05

 Times Cited Count:15 Percentile:65.72(Radiology, Nuclear Medicine & Medical Imaging)

Journal Articles

Clinical significance of L-type amino acid transporter 1 expression as a prognostic marker and potential of new targeting therapy in biliary tract cancer

Kaira, Kyoichi*; Sunose, Yutaka*; Ohshima, Yasuhiro; Ishioka, Noriko; Arakawa, Kazuhisa*; Ogawa, Tetsushi*; Sunaga, Noriaki*; Shimizu, Kimihiro*; Tominaga, Hideyuki*; Oriuchi, Noboru*; et al.

BMC Cancer, 13, p.482_1 - 482_12, 2013/10

 Times Cited Count:51 Percentile:85.76(Oncology)

Journal Articles

Biological evaluation of 3-[$$^{18}$$F]fluoro-$$alpha$$-methyl-D-tyrosine (D-[$$^{18}$$F]FAMT) as a novel amino acid tracer for positron emission tomography

Ohshima, Yasuhiro; Hanaoka, Hirofumi*; Tominaga, Hideyuki*; Kanai, Yoshikatsu*; Kaira, Kyoichi*; Yamaguchi, Aiko*; Nagamori, Shushi*; Oriuchi, Noboru*; Tsushima, Yoshito*; Endo, Keigo*; et al.

Annals of Nuclear Medicine, 27(4), p.314 - 324, 2013/05

 Times Cited Count:13 Percentile:51.48(Radiology, Nuclear Medicine & Medical Imaging)

Journal Articles

Synthesis of radioiodinated antitumor cyclic peptide, [$$^{125}$$I]-sansalvamide A derivative

Watanabe, Shigeki; Yamada, Keiichi*; Tsukui, Narutaka*; Hanaoka, Hirofumi*; Ohshima, Yasuhiro; Yamaguchi, Aiko*; Oku, Hiroyuki*; Ishioka, Noriko

JAEA-Review 2012-046, JAEA Takasaki Annual Report 2011, P. 88, 2013/01

Journal Articles

The H-Invitational Database (H-InvDB); A Comprehensive annotation resource for human genes and transcripts

Yamasaki, Chisato*; Murakami, Katsuhiko*; Fujii, Yasuyuki*; Sato, Yoshiharu*; Harada, Erimi*; Takeda, Junichi*; Taniya, Takayuki*; Sakate, Ryuichi*; Kikugawa, Shingo*; Shimada, Makoto*; et al.

Nucleic Acids Research, 36(Database), p.D793 - D799, 2008/01

 Times Cited Count:51 Percentile:74.53(Biochemistry & Molecular Biology)

Here we report the new features and improvements in our latest release of the H-Invitational Database, a comprehensive annotation resource for human genes and transcripts. H-InvDB, originally developed as an integrated database of the human transcriptome based on extensive annotation of large sets of fulllength cDNA (FLcDNA) clones, now provides annotation for 120 558 human mRNAs extracted from the International Nucleotide Sequence Databases (INSD), in addition to 54 978 human FLcDNAs, in the latest release H-InvDB. We mapped those human transcripts onto the human genome sequences (NCBI build 36.1) and determined 34 699 human gene clusters, which could define 34 057 protein-coding and 642 non-protein-coding loci; 858 transcribed loci overlapped with predicted pseudogenes.

Oral presentation

Synthesis and in vivo evaluation of radiohalogen-labeled antitumor cyclic peptides

Yamada, Keiichi*; Watanabe, Shigeki; Ohshima, Yasuhiro; Hanaoka, Hirofumi*; Tsukui, Narutaka*; Takano, Chikako*; Yamaguchi, Aiko*; Oku, Hiroyuki*; Ishioka, Noriko

no journal, , 

Oral presentation

Synthesis and evaluation of $$^{125}$$I labeled cyclic peptide, Sansalvamide A

Watanabe, Shigeki; Yamada, Keiichi*; Hanaoka, Hirofumi*; Ohshima, Yasuhiro; Tsukui, Narutaka*; Takano, Chikako*; Yamaguchi, Aiko*; Oku, Hiroyuki*; Iida, Yasuhiko*; Endo, Keigo*; et al.

no journal, , 

no abstracts in English

Oral presentation

Biological evaluation of 3-[$$^{18}$$F]fluoro-$$alpha$$-methyl-D-tyrosine (D-[$$^{18}$$F]FAMT) as a novel amino acid tracer for positron emission tomography

Ohshima, Yasuhiro; Hanaoka, Hirofumi*; Tominaga, Hideyuki*; Kanai, Yoshikatsu*; Kaira, Kyoichi*; Yamaguchi, Aiko*; Nagamori, Shushi*; Oriuchi, Noboru*; Tsushima, Yoshito*; Endo, Keigo*; et al.

no journal, , 

no abstracts in English

Oral presentation

Biological evaluation of 3-[$$^{18}$$F]fluoro-$$alpha$$-methyl-D-tyrosine (D-[$$^{18}$$F]FAMT) as a novel amino acid tracer for positron emission tomography

Ohshima, Yasuhiro; Hanaoka, Hirofumi*; Tominaga, Hideyuki*; Kanai, Yoshikatsu*; Kaira, Kyoichi*; Yamaguchi, Aiko*; Nagamori, Shushi*; Oriuchi, Noboru*; Tsushima, Yoshito*; Endo, Keigo*; et al.

no journal, , 

Oral presentation

Development of a cyclic peptide for treatment of intractable breast cancer

Watanabe, Shigeki; Yamada, Keiichi*; Hanaoka, Hirofumi*; Ohshima, Yasuhiro; Takano, Chikako*; Tsukui, Narutaka*; Yamaguchi, Aiko*; Sugo, Yumi; Oku, Hiroyuki*; Ishioka, Noriko

no journal, , 

no abstracts in English

Oral presentation

Studies on PET imaging of cancer Using Cu-64 ions

Sugo, Yumi; Ohshima, Yasuhiro; Yamaguchi, Aiko*; Hanaoka, Hirofumi*; Ishioka, Noriko

no journal, , 

no abstracts in English

Oral presentation

Development of 2-$$^{76}$$Br-bromo-$$alpha$$-methyl-L-phenylalanine as a novel $$^{76}$$Br-labeled PET tracer

Ohshima, Yasuhiro; Hanaoka, Hirofumi*; Suzuki, Yurika*; Yamaguchi, Aiko*; Watanabe, Shigeki; Uehara, Tomoya*; Nagamori, Shushi*; Kanai, Yoshikatsu*; Ishioka, Noriko; Tsushima, Yoshito*; et al.

no journal, , 

no abstracts in English

14 (Records 1-14 displayed on this page)
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