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Nakamura, Takemi; Horiguchi, Hironori; Yanagie, Hironobu*; Arai, Masaji
JAEA-Technology 2014-016, 61 Pages, 2014/06
JAEA-Technology-2014-016.pdf:30.48MB
In the department of research reactor and tandem accelerator, developments of irradiation technique with application enlargement for breast cancer on BNCT have been performed in the second medium term plans. We compiled this report about the technological development to solve several problems with the irradiation of breast cancer in the medical irradiation facility of JRR-4. In the present study, design fabrication of a collimator for breast cancer, dose evaluation analysis by clinical model, investigation of dose enhancement at deeper region and investigation of fixing method for breast cancer irradiation were studied. By these evaluation results, we verified that the developed breast cancer irradiation technique can be applied to BNCT medical irradiation of JRR-4. These results are expected to be able to contribute to breast cancer irradiation techniques of other reactor-based BNCT and future accelerator-based BNCT.
Horiguchi, Hironori; Nakamura, Takemi; Kumada, Hiroaki*; Yanagie, Hironobu*; Suzuki, Minoru*; Sagawa, Hisashi
Proceedings of 14th International Congress on Neutron Capture Therapy (ICNCT-14) (CD-ROM), p.234 - 237, 2010/10
Recurrent breast cancer has been considered the application for boron neutron capture therapy using the JRR-4. The investigation of irradiation conditions for the recurrent breast cancer was performed by simulation with the JCDS. We performed the preliminary dosimetry of the model to verify the efficient irradiation conditions such as the neutron energy modes and multiple field technique. From the result, when the 30 Gy-Eq dose as minimum dose was delivered to the cancers, comparable dose distribution was delivered at the healthy tissues by both a one-port irradiation from anterior direction and a two-port irradiation from tangential direction. We revealed that the two-port irradiation was not valid to reduce the healthy tissues dose due to the isotopic scattering of neutrons in the body. We concluded that the optimal irradiation condition was the one-port irradiation with thermal neutron beam mode in terms of less healthy tissues dose and shorter irradiation time.
Yanagie, Hironobu*; Kumada, Hiroaki*; Nakamura, Takemi; Higashi, Shushi*; Ikushima, Ichiro*; Morishita, Yasuyuki*; Shinohara, Atsuko*; Fujiwara, Mitsuteru*; Suzuki, Minoru*; Sakurai, Yoshinori*; et al.
Proceedings of 14th International Congress on Neutron Capture Therapy (ICNCT-14) (CD-ROM), p.157 - 160, 2010/10
Yanagie, Hironobu*; Sakurai, Yoshinori*; Kumada, Hiroaki; Naka, Hideji*; Furuya, Yoshitaka*; Takamoto, Shinichi*; Ono, Koji*; Takahashi, Hiroyuki*
no journal, ,
no abstracts in English
Horiguchi, Hironori; Nakamura, Takemi; Yanagie, Hironobu*; Sagawa, Hisashi
no journal, ,
no abstracts in English