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Yanagisawa, Kayo; Matsueda, Makoto; Furukawa, Makoto*; Ishiniwa, Hiroko*; Wada, Toshihiro*; Hirata, Takafumi*; Takagai, Yoshitaka*
Analyst, 148(18), p.4291 - 4299, 2023/09
Times Cited Count:0 Percentile:0.00(Chemistry, Analytical)Quantitative imaging of trace elements was successfully performed by online isotope dilution laser ablation inductively coupled plasma mass spectrometry (online LA-ICP-IDMS). The sample aerosols produced by LA are mixed online with the mist created from an isotopically enriched spike solution via an in-house cyclonic spray chamber, which has a gas port on the top. Quantification was continuously achieved in each spot; subsequently, quantitative imaging was realized. Fe and Sr were selected as the model elements, and their spot quantifications based on online-isotope dilution. The method was applied to actual biological hard tissues, and the results were compared with electron probe microanalyzer data.
Yanagisawa, Kayo; Matsueda, Makoto; Furukawa, Makoto*; Takagai, Yoshitaka*
Analytical Sciences, 38(8), p.1105 - 1114, 2022/08
We demonstrate the sensitivity enhancement in inductively coupled plasma mass spectrometry (ICP-MS) by combining ultrasonic nebulization via the nitrogen mixed gas effect. We showed the effect of nitrogen gas concentration (0-5%) in the nebulizer gas on the signal sensitivity for 63 elements using commercially available (concentric and ultrasonic) nebulizers. In addition, the limit of detection was calculated in each case. Finally, we compared the sensitivity (i.e., the slope of the calibration curve), background noise intensity, and three-dimensional intensity distribution in the plasma to elucidate the effects of the concurrent use of mixed gas plasmas and nebulization methods.
Yanagisawa, Kayo*; Odashima, Mizuki*; Matsueda, Makoto; Furukawa, Makoto*; Takagai, Yoshitaka*
Talanta, 244, p.123442_1 - 123442_7, 2022/07
Times Cited Count:3 Percentile:41.05(Chemistry, Analytical)The determination of a low concentration of Sr was achieved by the combination of online SPE-ICP-QMS and ID method using Sr/Sr ratio. No requirement of radioactive standard material and the preparation process of the calibration curve was in the quantification process and data acquisition can be in one-shot sample injection. The proposed method allowed the rapid (within 15 min/sample) quantification of Sr in the presence of significant interferences such as isobaric Zr and other elements. The LOD for Sr was 5.6 Bq/L for a 10 mL injection and this could be improved by simply increasing the sample volume injected.
Koarai, Kazuma; Matsueda, Makoto; Aoki, Jo; Yanagisawa, Kayo*; Fujiwara, Kenso; Terashima, Motoki
KEK Proceedings 2021-2, p.140 - 145, 2021/12
Strontium-90 and Y, its daughter nuclide, adverse effects on the bone marrow. Monitoring of Sr in the bones have been required after the Fukushima-Daiichi Nuclear Power Plant accident. However, conventional radioactivity measurement method for Sr requires a complicated separation of Y and a time-consuming measurement. ICP-MS system has been applied to Sr concentration survey of water, soil, and edible part of fish. We developed measurement method of Sr with ICP-MS and applied the method for cattle bones. We determined Sr in the hard tissues of animals that collected in the Fukushima prefecture. Limit of detection in the measurement was 19 Bq/kg.
Koarai, Kazuma; Matsueda, Makoto; Aoki, Jo; Yanagisawa, Kayo*; Terashima, Motoki; Fujiwara, Kenso; Kino, Yasushi*; Oka, Toshitaka; Takahashi, Atsushi*; Suzuki, Toshihiko*; et al.
Journal of Analytical Atomic Spectrometry, 36(8), p.1678 - 1682, 2021/08
Times Cited Count:5 Percentile:53.20(Chemistry, Analytical)Rapid analysis of Sr in bone and tooth samples of cattle were achieved by an inductively coupled plasma mass spectrometry (ICP-MS) coupled with mass shift and solid phase extraction techniques. Limit of detection (LOD) in the ICP-MS measurement of 0.1 g samples was lower than that of the radioactivity measurement. Analytical time of the ICP-MS method was reduced from 20 days to 11 hours, compared with the radiometric method. Therefore, the ICP-MS method can be rapid and useful procedure of Sr in small bone and tooth samples derived from terrestrial animals.
Matsueda, Makoto; Yanagisawa, Kayo*; Koarai, Kazuma; Terashima, Motoki; Fujiwara, Kenso; Abe, Hironobu; Kitamura, Akihiro; Takagai, Yoshitaka*
ACS Omega (Internet), 6(29), p.19281 - 19290, 2021/07
Times Cited Count:2 Percentile:13.70(Chemistry, Multidisciplinary)Online solid-phase extraction-inductively coupled plasma-quadrupole mass spectrometry with oxygen dynamic reaction cell (online SPE-ICP-MS-DRC) was shown to be a thorough automatic analytical system, circumventing the need for human handling. At three stepwise separations (SPE-DRC-Q mass filters), we showed that interference materials allowed the coexistence of abundance ratios of 1.510 for Tc/Mo. Using this optimized system, a detection limit of Tc was 9.3 pg/L (5.9 mBq/L) for a 50 mL injection and sequential measurements were undertaken at a cycle of 24 min/sample.
Koarai, Kazuma; Matsueda, Makoto; Aoki, Jo; Yanagisawa, Kayo*; Fujiwara, Kenso; Terashima, Motoki; Kitamura, Akihiro; Abe, Hironobu
KEK Proceedings 2020-4, p.180 - 185, 2020/11
Strontium-90 and Y, its daughter nuclide, adverse effects on the bone marrow. Monitoring of Sr in the bones have been required after the Fukushima-Daiichi Nuclear Power Plant accident. However, conventional radioactivity measurement method for Sr requires a complicated separation of Y and a time-consuming measurement. ICP-MS system has been applied to Sr concentration survey of water, soil, and edible part of fish. We applied the ICP-MS system for the bones for the first time. In this study, reference bone (JSAC 0785 fish bone) was used as measurement samples. Sample preparation of the bone was performed using a microwave digestion instrument. After sample preparation, Sr was determined using ICP-MS system with cascade separation steps based on on-line column separation and oxygen reaction. Strontium-90 in the bones was successfully separated from Ca, Ba, Y, Zr, Fe, Se, and Ge, which interfered in ICP-MS measurement, in the separation steps.
Yanagisawa, Kayo*; Matsueda, Makoto; Furukawa, Makoto*; Takagai, Yoshitaka*
Analytical Sciences, 36(9), p.1131 - 1135, 2020/09
Times Cited Count:4 Percentile:21.51(Chemistry, Analytical)In this paper, we propose an online water infusion system for rapid quantification of radioactive strontium-90 (Sr) with inductively coupled plasma mass spectrometry coupled solid-phase extraction and O dynamic reaction (cascade ICP-MS). The proposed system automatically provides a higher dilution ratio, which is at most 3.3 times the ratio obtained by the previous method, without increasing the analysis time (within 15 min). A detection limit of 2.7 Bq/kg wet (0.54 pg/kg wet) was achieved. The recovery test results were consistent with two different spiked values.
Fujiwara, Kenso; Yanagisawa, Kayo*; Iijima, Kazuki
Environmental Radiochemical Analysis VI, p.89 - 96, 2019/09
Since Strontium-90 (Sr-90) is one of the high yield and hazardous fission products, accurate and low-level detection of Sr-90 is essential for environmental samples. Especially, in case of nuclear power plant accidents, rapid and precise assessment of Sr-90 for environmental monitoring and health physics is required. In order to evaluate the migration of radionuclides in the environment, not only Sr-90 in water but also those in soil and biological samples should be measured. A new method for rapid quantification of Sr-90 by online solid phase extraction coupled with inductively coupled plasma mass spectrometry (SPE-ICP-MS) has been developed. In this method, it is unavoidable to eliminate the interference by polyatomic ion (e.g., ArCa, Ca) induced by isotopes and matrices in fishes and soil. In this study, SPE-ICP-MS method was applied to the measurement of Sr-90 in fishes, and the influence of the Sr isotopes and coexisting ions such as Ca was evaluated.
Saegusa, Jun; Yanagisawa, Kayo; Hasumi, Atsushi; Shimizu, Takenori; Uchida, Yoshiaki*
Radiation Physics and Chemistry, 137, p.210 - 215, 2017/08
Times Cited Count:1 Percentile:10.50(Chemistry, Physical)Following the Fukushima Daiichi Nuclear Power Plant (NPP) accident, large-scale radiation monitoring and environmental clean-up activities have been conducted throughout the Fukushima region. Outside air temperatures there reach 40C in summer and -20C in winter, which are beyond the quoted range of many radiation survey instruments. For the purpose, temperature performances of four types of portable Japanese survey instruments which are widely used in Fukushima were experimentally investigated with a temperature-controlled chamber.
Matsueda, Makoto; Koarai, Kazuma; Yanagisawa, Kayo*; Fujiwara, Kenso; Kitamura, Akihiro
no journal, ,
Sr-90 accumulates in hard tissues such as bones and teeth in the case of uptake into the human or animal bodies. Therefore, the analysis of these hard tissues from the viewpoint of exposure evaluation has required, but the conventional radioactivity analysis requires a period of about one month, it is difficult to process a large number of samples. From this thing, we tried to apply application of the online solid phase extraction/ICP-MS method which can be measured quickly compared to radioactivity analysis. This method has mainly been utilizing as the analysis of Sr-90 contained in the water samples such as rainwater, and it has already equipped the correction functions corresponding to the shift of recovery rate at the Sr resin and the sensitivity shift in ICP-MS. However, hard tissues contain a large amount of matrix. Therefore, we investigated whether the isobaric interference, stable Sr, and other high matrix influence to Sr-90 values and attempted to correct the values.
Koarai, Kazuma; Matsueda, Makoto; Aoki, Jo; Yanagisawa, Kayo*; Fujiwara, Kenso; Terashima, Motoki; Kitamura, Akihiro; Abe, Hironobu
no journal, ,
Strontium-90 and Y, its daughter nuclide, adverse effects on the bone marrow. Monitoring of Sr in the bones have been required after the Fukushima-Daiichi Nuclear Power Plant accident. However, conventional radioactivity measurement method for Sr requires a complicated separation of Y and a time-consuming measurement. ICP-MS system has been applied to Sr concentration survey of water, soil, and edible part of fish. We applied the ICP-MS system for the bones. We determined Sr in the hard tissues of animals that collected in the Fukushima prefecture. Limit of detection in the measurement was 19 Bq/kg.
Koarai, Kazuma; Matsueda, Makoto; Aoki, Jo; Yanagisawa, Kayo*; Fujiwara, Kenso; Terashima, Motoki; Kino, Yasushi*; Oka, Toshitaka; Okutsu, Kenichi*; Yamashita, Takuma*; et al.
no journal, ,
We demonstrated a method of Sr measurement in small pieces of hard tissues with radioactivity measurement or ICP-MS measurement. Interference elements of the measurements were removed by chemical separation. We could determine Sr in 0.1 g of hard tissues by radioactivity measurement method and ICP-MS method. Limit of detection of the ICP-MS method was lower than that of the radioactivity measurement. The ICP-MS method is adequate method for distribution analysis of Sr in the hard tissues.
Matsueda, Makoto; Yanagisawa, Kayo*; Koarai, Kazuma; Terashima, Motoki; Fujiwara, Kenso; Abe, Hironobu; Kitamura, Akihiro; Takagai, Yoshitaka*
no journal, ,
no abstracts in English
Yanagisawa, Kayo*; Kuwata, Haruka*; Hagiwara, Hiroki; Uezu, Yasuhiro
no journal, ,
no abstracts in English
Koarai, Kazuma; Matsueda, Makoto; Aoki, Jo; Yanagisawa, Kayo*; Terashima, Motoki; Fujiwara, Kenso; Kino, Yasushi*; Oka, Toshitaka; Takahashi, Atsushi*; Suzuki, Toshihiko*; et al.
no journal, ,
Rapid analysis of Sr in bone and tooth samples of cattle were achieved by an inductively coupled plasma mass spectrometry (ICP-MS) coupled with mass shift and solid phase extraction techniques. Limit of detection (LOD) in the ICP-MS measurement of 0.1 g samples was lower than that of the radioactivity measurement. Analytical time of the ICP-MS method was reduced from 20 days to 11 hours, compared with the radiometric method. Therefore, the ICP-MS method can be rapid and useful procedure of Sr in small bone and tooth samples derived from terrestrial animals.
Koarai, Kazuma; Matsueda, Makoto; Aoki, Jo; Yanagisawa, Kayo*; Terashima, Motoki; Fujiwara, Kenso; Kino, Yasushi*; Oka, Toshitaka; Takahashi, Atsushi*; Suzuki, Toshihiko*; et al.
no journal, ,
Rapid analysis of Sr in bone and tooth samples of cattle were achieved by an inductively coupled plasma mass spectrometry (ICP-MS) coupled with mass shift and solid phase extraction techniques. Limit of detection (LOD) in the ICP-MS measurement of 0.1 g samples was lower than that of the radioactivity measurement. Analytical time of the ICP-MS method was reduced from 20 days to 11 hours, compared with the radiometric method. The ICP-MS method was improved by ICP-MS/MS and oxygen-ammonia mixed gas reaction.
Yanagisawa, Kayo; Matsueda, Makoto; Furukawa, Makoto*; Hirata, Takafumi*; Takagai, Yoshitaka*
no journal, ,
Sr-90 has chemical properties similar to those of Ca and is locally deposited in bones and teeth after being taken into the body. The environmental transfer and metabolism in the body have attracted much interest since the accident at the Fukushima Daiichi Nuclear Power Plant (1F). Laser ablation (LA)-ICP-MS is a direct solid-state analysis method with excellent sensitivity and spatial resolution, making it useful for imaging analysis to obtain images of elemental distributions on the surface layer of analytes. However, it has been difficult to accurately detect trace amounts of Sr-90 due to interference from isobaric and polyatomic ions with mass-to-charge ratios (m/z) close to Sr-90. This method shows that Sr-90 distribution on the sample surface can be determined even in the presence of interfering elements by using LA-ICP-MS/MS equipped with a dynamic reaction cell (DRC).
Yanagisawa, Kayo; Matsueda, Makoto; Furukawa, Makoto*; Hirata, Takafumi*; Takagai, Yoshitaka*
no journal, ,
LA-ICP-MS technique, both the elemental and isotopic mapping analyses can be made with high sensitivity over the traditional techniques such as XRF, EPMA, and SIMS. However, detection of Sr-90 is still challenging because of contributions of spectral interferences and tailing from neighboring abundant isotopes. To reduce the contribution of various interferences, ICP-MS/MS and reaction cell technique was adopted in this study. With the present analytical technique, the detection limit obtained from analysis area (100100 m square) was 0.64 mBq. The measured background intensity at m/z 90 u (1.62.2 cps) did not change significantly even under the presence of various interfering elements (Ni: 2,084 mg/kg, Ge: 21 mg/kg, Y: 23,004 mg/kg, Zr: 175 mg/kg). The measured abundance sensitivity on Sr-90 from Sr-88 was 2.6e-9. The data indicates sensitive and rapid analytical technique for the mapping analysis of both Sr-90 and other trace-elements.
Yanagisawa, Kayo; Matsueda, Makoto; Furukawa, Makoto*; Hirata, Takafumi*; Takagai, Yoshitaka*
no journal, ,
Determinations of radioisotopes in fuel debris and radioactive wastes are important for decommissioning of Fukushima Daiichi Nuclear Power Plant. Difficult-to-measure radioisotopes such as Sr-90 have been measured by radiometric analysis and inductively coupled plasma-mass spectrometry (ICP-MS), the methods have not achieved the distribution of the radioisotopes on the sample's surface due to its digestion process of the samples before measurements. Laser ablation (LA)-ICP-MS can obtain the distribution information of radionuclides directly on the surface of solid samples. In contrast, the quantification with the method is difficult caused by the spectral interferences and matrix effects from samples. In this study, a quantification method was developed combined with LA-ICP-MS and isotope dilution method. The proposed method was applied for Sr-90 quantification.