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Journal Articles

Radon inhalation decreases DNA damage induced by oxidative stress in mouse organs via the activation of antioxidative functions

Kataoka, Takahiro*; Shuto, Hina*; Naoe, Shota*; Yano, Junki*; Kanzaki, Norie; Sakoda, Akihiro; Tanaka, Hiroshi; Hanamoto, Katsumi*; Mitsunobu, Fumihiro*; Terato, Hiroaki*; et al.

Journal of Radiation Research (Internet), 62(5), p.861 - 867, 2021/09

 Times Cited Count:5 Percentile:55.27(Biology)

Journal Articles

Evaluation of the redox state in mouse organs following radon inhalation

Kataoka, Takahiro*; Kanzaki, Norie; Sakoda, Akihiro; Shuto, Hina*; Yano, Junki*; Naoe, Shota*; Tanaka, Hiroshi; Hanamoto, Katsumi*; Terato, Hiroaki*; Mitsunobu, Fumihiro*; et al.

Journal of Radiation Research (Internet), 62(2), p.206 - 216, 2021/03

AA2020-0273.pdf:1.2MB

 Times Cited Count:6 Percentile:61.83(Biology)

Radon inhalation activates antioxidative functions in mouse organs, thereby contributing to inhibition of oxidative stress-induced damage. Therefore, in this study, we evaluated the redox state of various organs in mice following radon inhalation. Mice inhaled radon at concentrations of 2 or 20 kBq/m$$^{3}$$ for 1, 3, or 10 days. The relationship between antioxidative function and oxidative stress was evaluated by principal component analysis (PCA) and correlation coefficient compared with control mice subjected to sham inhalation. These findings suggested that radon inhalation altered the redox state in organs, but that the characteristics varied depending on the redox state in organs.

Journal Articles

Identified charged hadron production in $$p + p$$ collisions at $$sqrt{s}$$ = 200 and 62.4 GeV

Adare, A.*; Afanasiev, S.*; Aidala, C.*; Ajitanand, N. N.*; Akiba, Yasuyuki*; Al-Bataineh, H.*; Alexander, J.*; Aoki, Kazuya*; Aphecetche, L.*; Armendariz, R.*; et al.

Physical Review C, 83(6), p.064903_1 - 064903_29, 2011/06

 Times Cited Count:184 Percentile:99.44(Physics, Nuclear)

Transverse momentum distributions and yields for $$pi^{pm}, K^{pm}, p$$, and $$bar{p}$$ in $$p + p$$ collisions at $$sqrt{s}$$ = 200 and 62.4 GeV at midrapidity are measured by the PHENIX experiment at the RHIC. We present the inverse slope parameter, mean transverse momentum, and yield per unit rapidity at each energy, and compare them to other measurements at different $$sqrt{s}$$ collisions. We also present the scaling properties such as $$m_T$$ and $$x_T$$ scaling and discuss the mechanism of the particle production in $$p + p$$ collisions. The measured spectra are compared to next-to-leading order perturbative QCD calculations.

Journal Articles

Azimuthal correlations of electrons from heavy-flavor decay with hadrons in $$p+p$$ and Au+Au collisions at $$sqrt{s_{NN}}$$ = 200 GeV

Adare, A.*; Afanasiev, S.*; Aidala, C.*; Ajitanand, N. N.*; Akiba, Yasuyuki*; Al-Bataineh, H.*; Alexander, J.*; Aoki, Kazuya*; Aphecetche, L.*; Aramaki, Y.*; et al.

Physical Review C, 83(4), p.044912_1 - 044912_16, 2011/04

 Times Cited Count:8 Percentile:49.7(Physics, Nuclear)

Measurements of electrons from the decay of open-heavy-flavor mesons have shown that the yields are suppressed in Au+Au collisions compared to expectations from binary-scaled $$p+p$$ collisions. Here we extend these studies to two particle correlations where one particle is an electron from the decay of a heavy flavor meson and the other is a charged hadron from either the decay of the heavy meson or from jet fragmentation. These measurements provide more detailed information about the interaction between heavy quarks and the quark-gluon matter. We find the away-side-jet shape and yield to be modified in Au+Au collisions compared to $$p+p$$ collisions.

Oral presentation

Evaluation of hydrogen peroxide induced oxidative stress by radon inhalation in mouse organs

Kataoka, Takahiro*; Kanzaki, Norie; Sakoda, Akihiro; Ishida, Tsuyoshi; Shuto, Hina*; Yano, Junki*; Tanaka, Hiroshi; Hanamoto, Katsumi*; Terato, Hiroaki*; Mitsunobu, Fumihiro*; et al.

no journal, , 

We have reported that radon inhalation activates antioxidative functions in mouse organs. These activation inhibits reactive oxygen species (ROS) induced oxidative stresses. Activation of antioxidative functions induced by radon inhalation probably due to the production of a small quantity of ROS. However, there were no reports on this mechanism. In this study, we evaluated hydrogen peroxide induced oxidative stress by radon inhalation in mouse organs. That is, mice inhaled radon at a concentration of 1 kBq/m$$^{3}$$ or 10 kBq/m$$^{3}$$ for 24 hours. Results showed that radon inhalation increased hydrogen peroxide in liver and lung by 20%. On the other hand, hydrogen peroxide in heart decreased by 20%. This is probably due to total glutathione reacts with hydrogen peroxide. These findings suggest that radon inhalation produces a small quantity of hydrogen peroxide, which is ROS, in mouse organs. However, antioxidative related substances, which are catalase and total glutathione, play an important role to reduce oxidative stress.

Oral presentation

A Basic study on the production of hydrogen peroxide by radon inhalation in mouse organs

Kataoka, Takahiro*; Kanzaki, Norie; Sakoda, Akihiro; Ishida, Tsuyoshi; Shuto, Hina*; Yano, Junki*; Tanaka, Hiroshi; Hanamoto, Katsumi*; Terato, Hiroaki*; Mitsunobu, Fumihiro*; et al.

no journal, , 

no abstracts in English

Oral presentation

Radon inhalation time dependent changes in the hydrogen peroxide production in mice organs

Kataoka, Takahiro*; Kanzaki, Norie; Sakoda, Akihiro; Shuto, Hina*; Yano, Junki*; Ishida, Tsuyoshi*; Tanaka, Hiroshi; Hanamoto, Katsumi*; Terato, Hiroaki*; Mitsunobu, Fumihiro*; et al.

no journal, , 

no abstracts in English

Oral presentation

Radon inhalation inhibits DNA damage induced by oxidative stress

Kataoka, Takahiro*; Kanzaki, Norie; Sakoda, Akihiro; Shuto, Hina*; Yano, Junki*; Naoe, Shota*; Tanaka, Hiroshi; Hanamoto, Katsumi*; Terato, Hiroaki*; Mitsunobu, Fumihiro*; et al.

no journal, , 

no abstracts in English

Oral presentation

Concentration dependence of suppression of DNA oxidative damage in mouse organs by radon inhalation

Masukawa, Yuki*; Kataoka, Takahiro*; Shuto, Hina*; Naoe, Shota*; Yano, Junki*; Kanzaki, Norie; Sakoda, Akihiro; Tanaka, Hiroshi; Hanamoto, Katsumi*; Mitsunobu, Fumihiro*; et al.

no journal, , 

no abstracts in English

Oral presentation

Inhibitory effects of thoron inhalation and ascorbic acid administration on acute alcohol induced hepatopathy in mice

Nishi, Soyoka*; Kataoka, Takahiro*; Ishida, Tsuyoshi*; Naoe, Shota*; Shuto, Hina*; Yano, Junki*; Kanzaki, Norie; Sakoda, Akihiro; Tanaka, Hiroshi; Mitsunobu, Fumihiro*; et al.

no journal, , 

no abstracts in English

Oral presentation

Study on change characteristics of cytokines in mouse serum by radon inhalation

Naoe, Shota*; Kataoka, Takahiro*; Yano, Junki*; Shuto, Hina*; Kanzaki, Norie; Sakoda, Akihiro; Yamaoka, Kiyonori*

no journal, , 

no abstracts in English

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