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Journal Articles

Order effect of repair processes to clustered DNA damage

Shiraishi, Iyo; Suzuki, Masao*; Shikazono, Naoya; Fujii, Kentaro; Yokoya, Akinari

Journal of Radiation Research, 55(Suppl.1), p.i92 - i93, 2014/03

Journal Articles

Dependence of the yields of AP sites and AP clusters produced in plasmid DNA on scavenging capacity and LET

Shiina, Takuya*; Watanabe, Ritsuko; Suzuki, Masao*; Yokoya, Akinari

Journal of Radiation Research, 55(Suppl.1), p.i15 - i16, 2014/03

BB2013-0476.pdf:0.21MB

Journal Articles

Live-cell imaging study of mitochondrial morphology in mammalian cells irradiated

Kanari, Yukiko; Noguchi, Miho; Kaminaga, Kiichi; Sakamoto, Yuka; Yokoya, Akinari

Journal of Radiation Research, 55(Suppl.1), p.i129 - i130, 2014/03

Journal Articles

Visualization of cell-cycle modification by ionizing irradiation in single HeLa cells using fluorescent ubiquitination-based cell-cycle indicator

Kaminaga, Kiichi; Sakamoto, Yuka; Kanari, Yukiko; Noguchi, Miho; Yokoya, Akinari

Journal of Radiation Research, 55(Suppl.1), p.i127 - i128, 2014/03

Journal Articles

Three-dimensional culture of HeLa-FUCCI cells for study of bystander cell cycle effect of high LET particles

Sakamoto, Yuka; Kaminaga, Kiichi; Kanari, Yukiko; Noguchi, Miho; Yokoya, Akinari

Journal of Radiation Research, 55(Suppl.1), p.i120 - i121, 2014/03

Journal Articles

Radiation-quality-dependent bystander effects induced by the microbeams with different radiation sources

Suzuki, Masao*; Autsavapromporn, N.*; Usami, Noriko*; Funayama, Tomoo; Plante, I.*; Yokota, Yuichiro; Muto, Yasuko*; Suzuki, Michiyo; Ikeda, Hiroko; Hattori, Yuya; et al.

Journal of Radiation Research, 55(Suppl.1), P. i54, 2014/03

Oral presentation

Systematic measurements of lineal energy distributions of various energetic heavy ion beams using a wall-less tissue equivalent proportional counter

Tsuda, Shuichi; Sato, Tatsuhiko; Watanabe, Ritsuko; Takada, Masashi*

no journal, , 

Deposit energy distribution in a microscopic site is basic information for understanding of biological effects of energetic heavy ion beams. To estimate relative biological effectiveness, RBE, lineal energy, y, is used in simulation models as a physical index because y can treat each energy deposition in a microdosimetric scale by a single event of both incident primary heavy ions and secondary particles. In the present work, using a wall-less tissue equivalent proportional counter, y distributions, yf(y), have been measured for various energetic heavy ions of $$^{1}$$H, $$^{2}$$He, $$^{12}$$C, $$^{28}$$Si and $$^{56}$$Fe, and compared with results by simulation codes. The results of yf(y) distributions obtained using a narrow-shape beam and radial dependence of yf(y) distributions will be also shown in the presentation, along with the calculation results by the PHITS code and a track structure simulation code TRACION.

Oral presentation

Astronaut dose estimation using the PHITS code in combination with realistic models of the Kibo module and the MATROSHKA phantom

Sato, Tatsuhiko; Nagamatsu, Aiko*; Takeda, Kazuo*; Niita, Koji*; Puchalska, M.*; Sihver, L.*; Reitz, G.*

no journal, , 

Estimation of organ doses and their mean quality factors for astronauts due to cosmic-ray exposure has been an essential issue in the planning of long-term space missions. We therefore performed simulation for calculating the organ doses and their mean quality factors inside the MATROSHKA phantom, using a realistic geometry of the Kibo module in combination with the NUNDO phantom, which was constructed based on the CT image of the phantom. The particle and heavy ion transport code system PHITS was employed in the simulation. From preliminary results, it is found that the calculated organ doses and their mean quality factors inside the MATROSHKA phantom agree with the corresponding experimental data fairly well.

Oral presentation

Exploration of the site responsible for the radiation response of the salt chemotaxis learning in ${it C. elegans}$ using heavy-ion microbeam

Sakashita, Tetsuya; Suzuki, Michiyo; Muto, Yasuko*; Hattori, Yuya; Ikeda, Hiroko; Yokota, Yuichiro; Funayama, Tomoo; Hamada, Nobuyuki*; Fukamoto, Kana*; Kobayashi, Yasuhiko

no journal, , 

An increasing body of data indicates that ionizing radiation causes learning impairments. To understand the effects of ionizing radiation on the nervous system, we have studied the salt chemotaxis learning in ${it Caenorhabditis elegans}$. We recently found the modulatory effect of $$gamma$$-rays on the salt chemotaxis learning that was manifested as a decrease in chemotaxis. However, we have no direct evidence for the interaction of ionizing radiation with the central neuronal tissue (nerve ring) of the nervous system in ${it C. elegans}$. Localized ionizing irradiation is useful to analyze radiation effects at a cellular or tissue level. Thus, to investigate the effects on the nerve ring, we used the heavy-ion microbeam system installed at the Takasaki Ion accelerators for Advanced Radiation Application of JAEA. In this presentation, we will discuss the preliminary results and a future vision of this study.

Oral presentation

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