Deuterated malonamide synthesis to probe interfacial mechanisms involved in solvent extraction process

Micheau, C.; 上田 祐生; 元川 竜平; 阿久津 和宏*

no journal, , 

Malonamide derivatives, were deuterated by using Pd/C and Rh/C catalysts in a DO/-propanol mixture. The maximum rate reached about 75 percents, determined by NMR and electrospray ionization mass spectrometry. The extraction behavior of the malonamides was unchanged by deuteration. Deuterated malonamides are a powerful tool for fundamental research on solvent extraction systems and for structural analysis of organic phases. The large difference in the neutron scattering cross section between protium and deuterium leads to a similarly large difference in neutron scattering length density of malonamide derivatives before and after deuteration. Therefore, using deuterated malonamides in small-angle neutron scattering and neutron reflectivity studies may help to reveal the nanoscopic structure of the specific solute species in the bulk organic phase and at the liquid liquid interface, respectively.