Application of Monte Carlo simulation and voxel models to internal dosimetry

木名瀬 栄; Mohammadi, A.; 高橋 聖

Applications of Monte Carlo Methods in Biology, Medicine and Other Fields of Science (Internet), p.41 - 53, 2011/02

At the Japan Atomic Energy Agency (JAEA), several studies have been conducted on the use of voxel models for internal dosimetry. Specific absorbed fractions (SAFs) and S values have been evaluated for preclinical assessments of radiopharmaceuticals using human voxel models and a mouse voxel model. Computational calibration of in vivo measurement system has been also made using Japanese and Caucasian voxel models, the knee and torso voxel models. In addition, for radiation protection of the environment, absorbed fractions (AFs) have been evaluated using a frog voxel model. Each study has been made by using Monte Carlo simulations. These data by Monte Carlo simulations and voxel models could adequately reproduce those by measurements. Voxel models are significant tools for internal dosimetry since the models are anatomically realistic.