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Ouchi, Kazuki; Ueno, Katsuhiro; Watanabe, Masayuki
Scientific Reports (Internet), 15, p.18515_1 - 18515_7, 2025/05
Times Cited Count:0We first demonstrate a nonaqueous rechargeable battery using uranium and iron as active materials. This uranium-iron battery achieves an open-circuit voltage of approximately 1.3 V, exhibits stable cycling performance, and delivers a good Coulombic efficiency of 862%. These characteristics suggest a promising avenue for utilizing depleted uranium in innovative applications.
Tsuchikawa, Yusuke; Kai, Tetsuya; Parker, J.*; Matsumoto, Yoshihiro*; Shinohara, Takenao
Scientific Reports (Internet), 15, p.7687_1 - 7687_8, 2025/03
Times Cited Count:1A neutron resonance absorption imaging technique to visualize two-dimensional distributions with element discrimination has been developed at the Materials and Life Science Experimental Facility of the Japan Proton Accelerator Research Complex. We measured neutron transmission spectra from 1 eV to 100 keV while rotating a sample containing iron, zirconium, nickel, molybdenum, and aluminum rods. The distributions of hafnium (impurity of zirconium) and molybdenum were clearly obtained by a straightforward analysis using the most prominent resonances. Then an analysis using multiple resonances of each element simultaneously was performed finding that the accuracy of elemental identification was improved, and iron and nickel distributions became clearer. However, these analysis methods sometimes have difficulties in the case of overlapping materials since a resonance shape can be deteriorated by those of other materials. Such an example was demonstrated with the case of iron and nickel. To overcome the issue and aiming for further improvement, we proposed a method to fit the transmission spectrum in a wide range assuming the existence of possible elements, successfully visualizing both the distributions of the sample metals and those of hafnium and manganese (impurities of zirconium and iron). The newly introduced analysis technique will contribute to the establishment of a standard analytical procedure for general users of the facility.
Chung, J.-H.*; Kwangwoo, S.*; Yokoo, Tetsuya R.; Ueta, Daichi*; Imai, Masaki; Kim, H.-S.; Kiem, D. H.; Han, M. J.*; Shamoto, Shinichi
Scientific Reports (Internet), 15, p.5978_1 - 5978_10, 2025/02
Times Cited Count:0 Percentile:0.00(Multidisciplinary Sciences)Mikhail, M. A. G.*; Kin, Tadahiro*; Eto, Taisei*; Tsukada, Kazuaki
Scientific Reports (Internet), 14, p.27132_1 - 27132_10, 2024/11
Times Cited Count:0 Percentile:0.00(Multidisciplinary Sciences)We have studied a straightforward and robust single-step cation exchange separation method to isolate medical copper radioisotopes Cu and
Cu produced in the
Zn(n, x) reaction with an accelerator neutrons technique. This study revealed the key role of a phosphate buffer pre-treatment of the cation exchange column in the separation process. It was found that incorporating the phosphate buffer into the column pre-treatment markedly enhances the retention of copper isotopes within the column throughout the separation procedure. This approach yields a high-purity radioactive copper sample with a high extraction efficiency of 94.4% of the initially produced copper, all within a relatively short experimental time frame of approximately 5 h for 100 g of starting material.
Oikawa, Kenichi; Matsumoto, Yoshihiro*; Watanabe, Kenichi*; Sato, Hirotaka*; Parker, J. D.*; Shinohara, Takenao; Kiyanagi, Yoshiaki*
Scientific Reports (Internet), 14, p.27990_1 - 27990_11, 2024/11
Times Cited Count:0 Percentile:0.00(Multidisciplinary Sciences)Kai, Takeshi; Toigawa, Tomohiro; Matsuya, Yusuke*; Hirata, Yuho; Tezuka, Tomoya*; Tsuchida, Hidetsugu*; Yokoya, Akinari*
Scientific Reports (Internet), 14, p.24722_1 - 24722_15, 2024/10
Times Cited Count:2 Percentile:0.00(Multidisciplinary Sciences)Scientific insight of water radiolysis is essential to estimate the direct and indirect effects of radiation DNA damage. Secondary electrons produced by water radiolysis are responsible for both effects. Here, we use a first-principles code to calculate the femtosecond dynamics of secondary electrons produced as a result of 20-30 eV energy deposition to water and analyze the formation mechanism of radiolytic chemical species produced in a nano-size ultra-small space region. From the results, it was clarified that the chemical species produced by water radiolysis begin to densify in the ultra-small region of a few nanometers when the deposition energy exceeds 25 eV. Our results provide important scientific insights into the formation of clustered DNA damage, which is believed to cause biological effects such as cell death.
Watanabe, Kenichi*; Sugai, Yusuke*; Hasegawa, Sota*; Tanaka, Seishiro*; Hitomi, Keitaro*; Nogami, Mitsuhiro*; Shinohara, Takenao; Su, Y. H.; Parker, J. D.*; Kockelmann, W.*
Scientific Reports (Internet), 14, p.25224_1 - 25224_13, 2024/10
Times Cited Count:0 Percentile:0.00(Multidisciplinary Sciences)Koizumi, Mitsuo; Ito, Fumiaki*; Lee, J.; Hironaka, Kota; Takahashi, Tone; Suzuki, Satoshi*; Arikawa, Yasunobu*; Abe, Yuki*; Lan, Z.*; Wei, T.*; et al.
Scientific Reports (Internet), 14, p.21916_1 - 21916_9, 2024/09
Times Cited Count:2 Percentile:0.00(Multidisciplinary Sciences)Tanabe, Kosuke*; Komeda, Masao; Toh, Yosuke; Kitamura, Yasunori*; Misawa, Tsuyoshi*; Tsuchiya, Kenichi*; Sagara, Hiroshi*
Scientific Reports (Internet), 14, p.18828_1 - 18828_10, 2024/08
Times Cited Count:0 Percentile:0.00(Multidisciplinary Sciences)Matsuya, Yusuke; Sato, Tatsuhiko; Kusumoto, Tamon*; Yachi, Yoshie*; Seino, Ryosuke*; Miwa, Misako*; Ishikawa, Masayori*; Matsuyama, Shigeo*; Fukunaga, Hisanori*
Scientific Reports (Internet), 14, p.16696_1 - 16696_14, 2024/07
Times Cited Count:3 Percentile:74.82(Multidisciplinary Sciences)Boron neutron capture therapy (BNCT) is a unique radiotherapy to selectively eradicate tumor cells using boron compounds (e.g., 4-borono-L-phenylalanine [BPA]) that are heterogeneously taken up at the cellular level. However, the impacts of tempo-spatial heterogenicity on cell killing remain unclear. With the technical combination of radiation track detector, cell cycle analysis, and biophysical simulations, we demonstrated the cell cycle-dependent heterogenicity of BPA uptake and following biological impacts of B(n,
)
Li reactions in HeLa cells expressing Fluorescent Ubiquitination-based Cell Cycle Indicators (FUCCI), as well as its modification effects of polyvinyl alcohol (PVA). As a result, we revealed that the intracellular BPA concentration in the S/G2/M phase was higher than that in the G1/S phase and that PVA modified the cell cycle dependence. Further, these findings lead to the development of the first BPA-PVA-based model for predicting BNCT treatment effects. These outcomes may contribute to more precision of therapeutic efficacy, when BNCT is combined with PVA and/or cell cycle-specific anticancer agents.
Yomogida, Takumi; Ouchi, Kazuki; Morii, Shiori; Oka, Toshitaka; Kitatsuji, Yoshihiro; Koma, Yoshikazu; Konno, Katsuhiro*
Scientific Reports (Internet), 14, p.14945_1 - 14945_11, 2024/06
Times Cited Count:1 Percentile:36.75(Multidisciplinary Sciences)Particles containing alpha () nuclides were identified from sediment in stagnant water in the Unit 3 reactor building of the Fukushima Daiichi Nuclear Power Station (FDiNPS). We analyzed different concentrations of alpha nuclides samples collected at two sampling sites, torus room and Main steam isolation valve (MSIV) room. Most of the
-nuclides in the stagnant water samples of the torus room and the MSIV room were present in particle fractions larger than 10
m. We detected uranium-bearing particles in
m-size by scanning electron microscopy-energy dispersive X-Ray (SEM-EDX) observation. Other short lived
-nuclides were detected by alpha track detection. The
-nuclide-containing particles with several tens to several hundred
m in size were mainly comprised iron (Fe) by SEM-EDX analysis. This study clarifies that the morphologies of U and other
-nuclides in the sediment of stagnant water in the FDiNPS's Unit 3 reactor building.
Matsuya, Yusuke; Sato, Tatsuhiko; Yachi, Yoshie*; Date, Hiroyuki*; Hamada, Nobuyuki*
Scientific Reports (Internet), 14, p.12160_1 - 12160_14, 2024/05
Times Cited Count:2 Percentile:74.82(Multidisciplinary Sciences)Understand mechanisms of radiation cataracts that are of concern in the field of radiation protection and radiation therapy. However, biological effects in HLEC following protracted exposure have not yet fully been explored. Here, we investigated the temporal kinetics of DNA double-strand breaks (DSBs) and cell survival of HLEC after exposure to photon beams at various dose rates, compared to those of human lung fibroblasts (WI-38). In parallel, we quantified the recovery for DSB and cell survival using a biophysical model. The study revealed that HLEC cells have a lower repair rate than WI-38 cells. There is no significant impact of dose rate on cell survival in both cell lines in the dose-rate range of 0.033-1.82 Gy/min. On the other hand, the experimental residual DSBs showed inverse dose rate effects (IDREs) compared to the model prediction, highlighting the importance of the IDREs in evaluating radiation effects on the ocular lens.
Nojima, Hitomi*; Kaida, Atsushi*; Matsuya, Yusuke; Uo, Motohiro*; Yoshimura, Ryoichi*; Arazi, L.*; Miura, Masahiko*
Scientific Reports (Internet), 14, p.11468_1 - 11468_13, 2024/05
Times Cited Count:0 Percentile:0.00(Multidisciplinary Sciences)Diffusing alpha-emitters radiation therapy (Alpha-DaRT) is a unique radiotherapy that uses seeds emitting alpha particles placed in solid tumors to kill cancer cells surrounding the seeds. Although the DNA damage response is an important cellular response that determines cell death after radiation; however, how DNA damage response occurs during Alpha-DaRT treatment has not yet been explored. In this study, we measured the spatiotemporal characteristics of the DNA damage response, including the number of DNA double-strand breaks and G2 arrest, during Alpha-DaRT treatment by cell experiments using HeLa cells expressing the Fucci cell cycle visualization system. As a result, we found a strong correlation between the number of alpha particles detected by solid-state track detector CR-39 and -H2AX staining, a marker for detecting DNA damage, and that the area of G2-arrested cells spread over a wider area up to 24 hours. In addition, time-lapse observations revealed that cell cycle dynamics change depending on the distance from the seed. The experimental model in this study revealed for the first time the spatiotemporal information of the DNA damage response around the seed during Alpha-DaRT treatment.
Iwata, Takuma*; Kosa, Towa*; Nishioka, Yukimi*; Owada, Kiyotaka*; Sumida, Kazuki; Annese, E.*; Kakoki, Masaaki*; Kuroda, Kenta*; Iwasawa, Hideaki*; Arita, Masashi*; et al.
Scientific Reports (Internet), 14, p.127_1 - 127_8, 2024/01
Times Cited Count:7 Percentile:89.50(Multidisciplinary Sciences)Ninomiya, Kazuhiko*; Kubo, Kenya*; Inagaki, Makoto*; Yoshida, Go*; Chiu, I.-H.; Kudo, Takuto*; Asari, Shunsuke*; Sentoku, Sawako*; Takeshita, Soshi*; Shimomura, Koichiro*; et al.
Scientific Reports (Internet), 14, p.1797_1 - 1797_8, 2024/01
Times Cited Count:0 Percentile:0.00(Multidisciplinary Sciences)The amount of C in steel, which is critical in determining its properties, is strongly influenced by steel production technology. We propose a novel method of quantifying the bulk C content in steel non-destructively using muons. This revolutionary method may be used not only in the quality control of steel in production, but also in analyzing precious steel archaeological artifacts. A negatively charged muon forms an atomic system owing to its negative charge, and is finally absorbed into the nucleus or decays to an electron. The lifetimes of muons differ significantly, depending on whether they are trapped by Fe or C atoms, and identifying the elemental content at the muon stoppage position is possible via muon lifetime measurements. The relationship between the muon capture probabilities of C/Fe and the elemental content of C exhibits a good linearity, and the C content in the steel may be quantitatively determined via muon lifetime measurements. Furthermore, by controlling the incident energies of the muons, they may be stopped in each layer of a stacked sample consisting of three types of steel plates with thicknesses of 0.5 mm, and we successfully determined the C contents in the range 0.20 - 1.03 wt% depth-selectively, without sample destruction.
Nozaki, Hiroshi*; Kondo, Hiroki*; Shinohara, Takenao; Setoyama, Daigo*; Matsumoto, Yoshihiro*; Sasaki, Tsuyoshi*; Isegawa, Kazuhisa*; Hayashida, Hirotoshi*
Scientific Reports (Internet), 13, p.22082_1 - 22082_8, 2023/12
Times Cited Count:3 Percentile:24.30(Multidisciplinary Sciences)Kobayashi, Keita; Okumura, Masahiko; Nakamura, Hiroki; Itakura, Mitsuhiro; Machida, Masahiko; Urata, Shingo*; Suzuya, Kentaro
Scientific Reports (Internet), 13, p.18721_1 - 18721_12, 2023/11
Times Cited Count:11 Percentile:74.59(Multidisciplinary Sciences)The first sharp peak diffraction peak (FSDP) in the structure factor of amorphous materials is thought to reflect the medium-range order structure in amorphous materials, and the structural origin of the FSDP has been a subject of ongoing debate. In this study, we employed machine learning molecular dynamics (MLMD) with nearly first-principles calculation accuracy to investigate the structural origin of the FSDP in high-density silica glass. First, we successfully reproduced various experimental data of high-density silica glass using MLMD. Furthermore, we revealed that the development (or reduction) of the FSDP in high-density silica glass is characterized by the deformation behavior of ring structures in Si-O covalent bond networks under compression.
Nabialek, A.*; Chumak, O. M.*; Aleshkevych, P.*; Domagala, J. Z.*; Pacewicz, A.*; Salski, B.*; Krupka, J.*; Seki, Takeshi*; Takanashi, Koki; Baczewski, L. T.*; et al.
Scientific Reports (Internet), 13, p.17016_1 - 170169, 2023/10
Times Cited Count:4 Percentile:50.15(Multidisciplinary Sciences)Asakawa, Kanta*; Fukutani, Katsuyuki; 3 of others*
Scientific Reports (Internet), 13, p.14965_1 - 14965_11, 2023/09
Times Cited Count:1 Percentile:13.37(Multidisciplinary Sciences)Kozawa, Tatsuya*; Fujihara, Masayoshi; Uchihara, Takeru*; Mitsuda, Setsuo*; Yano, Shinichiro*; Tamatsukuri, Hiromu; Munakata, Koji*; Nakao, Akiko*
Scientific Reports (Internet), 13, p.13750_1 - 13750_8, 2023/08
Times Cited Count:2 Percentile:22.21(Multidisciplinary Sciences)In condensed matter physics, pressure is frequently used to modify the stability of both electronic states and atomic arrangements. Under isotropic pressure, the intermetallic compound MnP has recently attracted attention for the interplay between pressure-induced superconductivity and complicated magnetic order in the vicinity. By contrast, we use uniaxial stress, a directional type of pressure, to investigate the effect on the magnetism and crystal structure of this compound. An irreversible magnetisation response induced by uniaxial stress is discovered in MnP at uniaxial stress as low as 0.04 GPa. Neutron diffraction experiments reveal that uniaxial stress forms crystal domains that satisfy pseudo-rotational symmetry unique to the MnP-type structure. The structure of the coexisting domains accounts for the stress-induced magnetism. We term this first discovered phenomenon atomic reconstruction (AR) induced by uniaxial stress. Furthermore, our calculation results provide guidelines on the search for AR candidates. AR allows crystal domain engineering to control anisotropic properties of materials, including dielectricity, elasticity, electrical conduction, magnetism and superconductivity. A wide-ranging exploration of potential AR candidates would ensure that crystal domain engineering yields unconventional methods to design functional multi-domain materials for a wide variety of purposes.