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布柴 達男*; 山内 理子*; 岩田 梨佳*; 佐藤 勝也; 大野 豊; 鳴海 一成*
JAEA-Review 2014-050, JAEA Takasaki Annual Report 2013, P. 124, 2015/03
The LOH (loss of heterozygosity) induction by various ion beam radiations was investigated in diploid . The ion beams C, C, He and Ar at the lowest dose of 37.5 Gy, which had 10% lethality, induced LOH with 590%) resulted from homologous recombination. Pol may be involved in the induction of LOH by ion beam radiations, because in the strain lacking Rev3, only slight induction of LOH was observed, whereas no remarkable effect of deletion for Pol was observed on ion beam induced LOH. In addition, the effects of extracts were examined on iron-beam radiation induced LOH, and ethanol extract of possessed inhibitory effect on LOH induced by C, He and Arion-beam radiation.