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JAEA Reports

User's manual of a supporting system for treatment planning in boron neutron capture therapy; JAERI computational dosimetry system

Kumada, Hiroaki; Torii, Yoshiya

JAERI-Data/Code 2002-018, 158 Pages, 2002/09


A boron neutron capture therapy (BNCT) with epithermal neutron beam is expected to treat effectively for malignant tumor that is located deeply in the brain. It is indispensable to estimate preliminarily the irradiation dose in the brain of a patient in order to perform the epithermal neutron beam BNCT. Thus, the JAERI Computational Dosimetry System (JCDS), which can calculate the dose distributions in the brain, has been developed. JCDS is a software that creates a 3-dimentional head model of a patient by using CT and MRI images and that generates a input data file automaticly for calculation neutron flux and gamma-ray dose distribution in the brain by the Monte Carlo code: MCNP, and that displays the dose distribution on the head model for dosimetry by using the MCNP calculation results. JCDS has any advantages as follows; By treating CT data and MRI data which are medical images, a detail three-dimensional model of patinet's head is able to be made easily. The three-dimensional head image is editable to simulate the state of a head after its surgical processes such as skin flap opening and bone removal for the BNCT with craniotomy that are being performed in Japan. JCDS can provide information for the Patient Setting System to set the patient in an actual irradiation position swiftly and accurately. This report describes basic design and procedure of dosimetry, operation manual, data and library structure for JCDS (ver.1.0)

Journal Articles

Comparison of patient brain dose measurements and the JCDS calculation

Yamamoto, Tetsuya*; Matsumura, Akira*; Yamamoto, Kazuyoshi; Kumada, Hiroaki; Torii, Yoshiya; Endo, Kiyoshi*; Matsushita, Akira*; Shibata, Yasushi*; Nose, Tadao*

Research and Development in Neutron Capture Therapy, p.415 - 418, 2002/09

Dose measurements in a patient's brain undergoing intraoperative BNCT (IOBNCT) were compared with calculations by a JAERI computational dosimetry system (JCDS). The maximum thermal neutron flux on the brain surface from the postirradiation measurement averaged 2.33$$pm$$0.37($$times$$10$$^{9}$$cm$$^{-2}$$s$$^{-1}$$) and the vascular boron dose averaged 11.4$$pm$$1.2 (9.6-12.7) Gy. Using JCDS, the maximum thermal neutron flux in the irradiated volume averaged 2.21$$pm$$0.33($$times$$10$$^{9}$$cm$$^{-2}$$s$$^{-1}$$), while the target vascular dose averaged 5.7 Gy and varied from 3.5 to 7.8 Gy. As such, in the dose planning for intra-operative irradiation, practical use of JCDS is recommended for uniform volume-dose control of postsurgical brain in IOBNCT.

Journal Articles

Basic and clinical studies for application of epithermal neutron beam for neutron capture therapy

Nose, Tadao*; Matsumura, Akira*; Yamamoto, Tetsuya*; Shibata, Yasushi*; Yoshida, Fumiyo*; Akutsu, Hiroyoshi*; Yasuda, Susumu*; Matsushita, Akira*; Nakai, Kei*; Yamada, Takashi*; et al.

UTRCN-G-29, p.114 - 123, 2001/00

no abstracts in English

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