Application of invasion mathematical model in dosimetry for boron neutron capture therapy for malignant glioma

Yamamoto, Kazuyoshi; Kumada, Hiroaki; Nakai, Kei*; Endo, Kiyoshi*; Yamamoto, Tetsuya*; Matsumura, Akira*

Proceedings of 11th World Congress on Neutron Capture Therapy (ISNCT-11) (CD-ROM), 14 Pages, 2004/10

A dose distribution considered the tumor cell density distribution is required on the radiation therapy. We propose a novel method of determining target region considering the tumor cell concentration as a new function for the next generation Boron Neutron Capture Therapy (BNCT) dosimetry system. It has not been able to sufficiently define the degree of microscopic diffuse invasion of the tumor cells peripheral to a tumor bulk in malignant glioma using current medical imaging. Referring to treatment protocol of BNCT, the target region surrounding the tumor bulk has been set as the region which expands at the optional distance with usual 2cm margin from the region enhanced on T1 weighted gadolinium Magnetic Resonance Imaging (MRI). In this research, the cell concentration of the region boundary of the target was discussed by using tumor cell diffusion model in the sphere spatio-temporal system. The survival tumor cell density distribution after the BNCT irradiation was predicted by the two regions diffusion model for a virtual brain phantom.

Evaluation of neutronic characteristic of irradiation field in MEU6-core; Comparison of neutron flux and neutron spectrum in MEU6-core and mixed-core

Nagao, Yoshiharu; Komukai, Bunsaku; Tabata, Toshio; Takeda, Takashi; Fujiki, Kazuo

JAERI-Tech 99-063, 57 Pages, 1999/08

JAERI-Tech-99-063.pdf:2.78MB

no abstracts in English

Magnetic flux motion of superconducting Bi-Sr-Ca-Cu-O films after ion irradiation

Hoshiya, Taiji; Takamura, Saburo; ;

Japanese Journal of Applied Physics, 29(8), p.L1443 - L1445, 1990/08

https://doi.org/10.1143/JJAP.29.L1443

no abstracts in English