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Sasaki, Yuto*; Sano, Aaru; Sasaki, Shinji; Iwamoto, Nobuyuki; Ouchi, Kazuki; Kitatsuji, Yoshihiro; Takaki, Naoyuki*; Maeda, Shigetaka
Journal of Nuclear Science and Technology, 61(4), p.509 - 520, 2024/04
Times Cited Count:4 Percentile:83.63(Nuclear Science & Technology)Ac is attracting attention as an alpha-emitting medical radioisotope. Since its demand is expected to increase, domestic production of Ac is required from the viewpoint of Japan's medical research and economic security. To establish the technical bases for the Ac production, JAEA has evaluated the radioactivity that can be produced in the experimental fast reactor Joyo and designed the concept that upgrades the existing facilities for transporting the irradiated target from Joyo to a neighboring PIE facility rapidly. Efficient Ac Separation from Ra irradiated in a fast reactor was studied. Ba and La were used as alternatives to Ra and Ac, respectively. By using DGA resin as an adsorbent, it can be expected that Ra and impurities generated by irradiation will be removed and Ac will be isolated. This study has revealed that Joyo can sufficiently produce Ac as a raw material for pharmaceuticals.
Sakamoto, Yoshiaki; Takebe, Shinichi; Ogawa, Hiromichi; Muraoka, Susumu; Ishii, Tomoaki*; Inagawa, Satoshi*; Gunji, Yasuyoshi*
Materials Research Society Symposium Proceedings, Vol.663, p.1207 - 1214, 2001/00
no abstracts in English
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Radioisotopes, 34, p.632 - 635, 1985/00
no abstracts in English
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Radioisotopes, 33(12), p.841 - 846, 1984/00
no abstracts in English
Iwahashi, Daiki*; Sasaki, Yuto*; Maeda, Shigetaka; Takaki, Naoyuki*
no journal, ,
Ac-225 is attracting attention as a radioisotope for targeted -therapy (TAT) used for the treatment of prostate cancer and the like. Therefore, we investigated a method of loading Ra-226 into the fast reactor Joyo and producing Ac-225 by transmutation. Ac-225 production can be expected by the (n,2n) reaction using fast neutrons in the center of the core and the (3n,) reaction using thermalized neutrons in the reflector region.
Takaki, Naoyuki*; Iwahashi, Daiki*; Sasaki, Yuto*; Maeda, Shigetaka
no journal, ,
We compared the production characteristics of Tc-99m and Ac-225 in the fast experimental reactor "Joyo" and commercial PWR, summarized the characteristics of each, and showed the possibility of domestic production of medical RI using domestic infrastructure.