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Journal Articles

Dosimetric dependence of ocular structures on eye size and shape for external radiation fields of electrons, photons, and neutrons

Furuta, Takuya; El Basha, D.*; Iyer, S. S. R.*; Correa Alfonso, C. M.*; Bolch, W. E.*

Journal of Radiological Protection, 39(3), p.825 - 837, 2019/09

 Times Cited Count:2 Percentile:21.95(Environmental Sciences)

Despite large variation of human eye, only one computational eye model has been adopted in almost all the radiation transport simulation studies. We thus adopted a new scalable and deformable eye model and studied the radiation exposure by electrons, photons, and neutrons in the standard radiation fields such as AP, PA, RLAT, ROT, by using Monte Carlo radiation transport code PHITS. We computed the radiation exposure for 5 eye models (standard, large, small, myopic, hyperopic) and analyzed influence of absorbed dose in ocular structures on eye size and shape. Dose distribution of electrons is conformal and therefore the absorbed doses in ocular structures depend on the depth location of each ocular structure. We thus found a significant variation of the absorbed doses for each ocular structure for electron exposure due to change of the depth location affected by eye size and shape. On the other hand only small variation was observed for photons and neutrons exposures because of less conformal dose distribution of those particles.

Journal Articles

A Scalable and deformable stylized model of the adult human eye for radiation dose assessment

El Basha, D.*; Furuta, Takuya; Iyer, S. S. R.*; Bolch, W. E.*

Physics in Medicine & Biology, 63(10), p.105017_1 - 105017_13, 2018/05

 Times Cited Count:9 Percentile:52.21(Engineering, Biomedical)

With recent changes in the recommended annual limit on eye lens exposures to ionizing radiation by International Commission on Radiological Protection, there is considerable interest in predictive computational dosimetry models of the human eye and its various ocular structures. Several computational eye models to date have been constructed for this purpose but they are typically constructed of nominal size and of a roughly spherical shape associated with the emmetropic eye. We therefore constructed a geometric eye model that is both scalable (allowing for changes in eye size) and deformable (allowing for changes in eye shape), and that is suitable for use in radiation transport studies of ocular exposures and radiation treatments of eye disease. As an example, electron and photon anterior-posterior radiation transport with the constructed eye model was conducted and analyzed resultant energy-dependent dose profiles. Due to anterior-posterior irradiation, the energy dose response was shifted to higher energy for a larger-size eye or an axially deformed eye in prolate shape because the structures were located in deeper depth compared to the normal eye.

Oral presentation

Development of a scalable and deformable stylized eye model and its application to the standard radiation exposure geometries

Furuta, Takuya; El Basha, D.*; Iyer, S. S. R.*; Correa Alfonso, C. M.*; Bolch, W. E.*

no journal, , 

With recent changes in the recommended annual dose limit on eye lens by International Commission on Radiological Protection, there is considerable interest in assessment of radiation exposure on eyes. Several Monte Carlo studies has been performed using a computational eye model. Although there are a large variety in size and shape for individual eyes, the eye model of one standard eye size and shape was adopted in most of those studies. We therefore constructed a geometric eye model that is both scalable (allowing for changes in eye size) and deformable (allowing for changes in eye shape), and studied dosimetry influence on the variation of the eye size and shape in the standard ICRP radiation geometries. We confirmed that only a trivial dependence on the eye size and shape, namely variation of the depth location of the ocular structures, was observed for radiation exposure in the broad radiation geometries.

Oral presentation

Development of a scalable and deformable stylized eye model for radiation dose assessment

Furuta, Takuya; El Basha, D.*; Iyer, S. S. R.*; Correa Alfonso, C. M.*; Bolch, W. E.*

no journal, , 

With recent changes in the recommended annual dose limit on eye lens by International Commission on Radiological Protection, several Monte Carlo studies has been performed using a computational eye model. Although there are a large variety in size and shape for individual eyes, the eye model of one standard eye size and shape was adopted in most of those studies. We therefore constructed a geometric eye model that is both scalable and deformable, and studied dosimetry influence on the variation of the eye size and shape in the standard radiation geometries using Monte Carlo radiation transport code PHITS. We confirmed that only a trivial dependence on the eye size and shape, namely variation of the depth location of the ocular structures, was observed for radiation exposure in the broad radiation geometries.

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