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Hirata, Yosuke*; Nakahara, Katsuhiko*; Sano, Akira*; Sato, Mitsuyoshi*; Aoyama, Yoshio; Miyamoto, Yasuaki; Yamaguchi, Hiromi; Nambu, Kenichi*; Takahashi, Hiroyuki*; Oda, Akinori*
Journal of Power and Energy Systems (Internet), 2(2), p.561 - 572, 2008/00
Hirata, Yosuke*; Nakahara, Katsuhiko*; Sano, Akira*; Sato, Mitsuyoshi*; Aoyama, Yoshio; Miyamoto, Yasuaki; Yamaguchi, Hiromi; Nambu, Kenichi*; Takahashi, Hiroyuki*; Oda, Akinori*
Proceedings of 15th International Conference on Nuclear Engineering (ICONE-15) (CD-ROM), 6 Pages, 2007/04
no abstracts in English
Yura, Kei; Shionyu, Masafumi*; Hagino, Kei*; Hijikata, Atsushi*; Hirashima, Yoshinori*; Nakahara, Taku*; Eguchi, Tatsuya*; Shinoda, Kazuki*; Yamaguchi, Akihiro*; Takahashi, Kenichi*; et al.
Gene, 380(2), p.63 - 71, 2006/10
Times Cited Count:55 Percentile:72.21(Genetics & Heredity)Alternative splicing is a molecular mechanism that produces multiple proteins from a single gene, and is thought to produce variety in proteins translated from a limited number of genes. Here we analyzed how alternative splicing produced variety in protein structure and function, by using human full-length cDNAs, on the assumption that all of the alternatively spliced mRNAs were translated to proteins. We found that the length of alternatively spliced amino acid sequences, in most cases, fell into a size shorter than that of average protein domain. We evaluated comprehensively the presumptive three-dimensional structures of the alternatively spliced products to assess the impact of alternative splicing on gene function. We found that more than half of the products encoded proteins which were involved in signal transduction, transcription and translation, and more than half of alternatively spliced regions comprised interaction sites between proteins and their binding partners, including substrates, DNA/RNA, and other proteins. Intriguingly, 67% of the alternatively spliced isoforms showed significant alterations to regions of the protein structural core, which likely resulted in large conformational change. Based on those findings, we speculate that there are a large number of cases that alternative splicing modulates protein networks through significant alteration in protein conformation.
Haba, Hiromitsu*; Tsukada, Kazuaki; Asai, Masato; Toyoshima, Atsushi; Akiyama, Kazuhiko; Nishinaka, Ichiro; Hirata, Masaru; Yaita, Tsuyoshi; Ichikawa, Shinichi; Nagame, Yuichiro; et al.
Journal of the American Chemical Society, 126(16), p.5219 - 5224, 2004/04
Times Cited Count:44 Percentile:72.46(Chemistry, Multidisciplinary)Fluoride complexation of element 104, rutherfordium (Rf), produced in the Cm(O,5n)Rf reaction has been studied by anion-exchange chromatography on an atom-at-a-time scale. The anion-exchangechromatographic behavior of Rf was investigated in 1.9-13.9 M hydrofluoric acid together with those of the group-4 elements Zr and Hf produced in the O-induced reactions on Ge and Gd targets, respectively. It was found that the adsorption behavior of Rf on anion-exchange resin is quite different from those of Zr and Hf, suggesting the influence of relativistic effect on the fluoride complexation of Rf.
Tsujimoto, Kazufumi; Kono, Nobuaki; Shinohara, Nobuo; Sakurai, Takeshi; Nakahara, Yoshinori; Mukaiyama, Takehiko; Raman, S.*
Nuclear Science and Engineering, 144(2), p.129 - 141, 2003/06
To evaluate neutron cross-section data of minor actinides, separated actinide samples and dosimetry samples were irradiated at the Dounreay Prototype Fast Reactor for 492 effective full power days. Based on the burnup calculations of major actinide and dosimetry samples, the neutron flux distribution and the flux level were adjusted at the locations where minor actinide samples were irradiated. The burnup calculations were carried out for minor actinides using the determined flux distribution and flux level. This paper discusses the burnup calculations and the validation of minor actinide cross-section data in evaluated nuclear data libraries. We find that we can obtain reliable FIMA (fission per initial metallic atom) values by using the Nd method except that the uncertainties in the FIMA values are large for U, Pu, Am isotopes, and Cm isotopes because the Nd yields are known poorly for these isotopes and are probably overestimated. For these isotopes, measurements to improve the fission-yield data are needed. We also find that, in general, the JENDL-3.2 nuclear data for the minor actinides are adequate for the conceptual design study of transmutation systems. But, there are some nuclides (especially Pu and Pu) for which new measurements are needed particulary if the minor actinides constitute a major part of the nuclear fuel.
Shinohara, Nobuo; Kono, Nobuaki; Nakahara, Yoshinori; Tsujimoto, Kazufumi; Sakurai, Takeshi; Mukaiyama, Takehiko*; Raman, S.*
Nuclear Science and Engineering, 144(2), p.115 - 128, 2003/06
no abstracts in English
Shinohara, Nobuo; Kono, Nobuaki; Nakahara, Yoshinori; Tsujimoto, Kazufumi; Sakurai, Takeshi; Mukaiyama, Takehiko*; Raman, S.*
Nuclear Science and Engineering, 144(2), p.115 - 128, 2003/06
Times Cited Count:12 Percentile:62.16(Nuclear Science & Technology)no abstracts in English
Tsujimoto, Kazufumi; Kono, Nobuaki; Shinohara, Nobuo; Sakurai, Takeshi; Nakahara, Yoshinori; Mukaiyama, Takehiko*; Raman, S.*
Nuclear Science and Engineering, 144(2), p.129 - 141, 2003/06
Times Cited Count:11 Percentile:59.28(Nuclear Science & Technology)no abstracts in English
Akiyama, Kazuhiko; Sueki, Keisuke*; Tsukada, Kazuaki; Yaita, Tsuyoshi; Miyake, Yoko*; Haba, Hiromitsu*; Asai, Masato; Kodama, Takeshi*; Kikuchi, Koichi*; Otsuki, Tsutomu*; et al.
Journal of Nuclear and Radiochemical Sciences, 3(1), p.151 - 154, 2002/06
The oxidation state of actinide elements encapsulated in fullerenes is studied. HPLC elution behavior of actinide-fullerenes is classified into two groups; the elution behavior of the first group, encapsulating U, Np, and Am, is similar to that of the light lanthanide-fullerenes, such as La, Ce, Pr, and Nd, while the behavior of the second group, encapsulating Th and Pa, is quite different from that of any lanthanide-fullerenes. The chemical species in the main HPLC elution peak of each group were identified as M@C82 and M@C84 (M = metal atom) from the mass of the U and Th fullerenes, respectively. The oxidation states of the U and Th atoms in the fullerenes were deduced to be 3+ and 4+, respectively, from the UV/vis/NIR absorption and XANES spectroscopy.
Shirasu, Noriko; Yamashita, Toshiyuki; Kanazawa, Hiroyuki; Kimura, Yasuhiko; Sudo, Kenji; Magara, Masaaki; Inagawa, Jun; Kono, Nobuaki; Nakahara, Yoshinori
JAERI-Research 2001-018, 23 Pages, 2001/03
no abstracts in English
Akiyama, Kazuhiko; Zhao, Y.*; Sueki, Keisuke*; Tsukada, Kazuaki; Haba, Hiromitsu; Nagame, Yuichiro; Kodama, Takeshi*; Suzuki, Shinzo*; Otsuki, Tsutomu*; Sakaguchi, Masahiko*; et al.
Journal of the American Chemical Society, 123(1), p.181 - 182, 2001/01
Times Cited Count:66 Percentile:84.89(Chemistry, Multidisciplinary)no abstracts in English
Tsukada, Kazuaki; Ichikawa, Shinichi; Hatsukawa, Yuichi; Nishinaka, Ichiro; ; Nagame, Yuichiro; Oura, Yasutsugu*; *; Sueki, Keisuke*; *; et al.
Physical Review C, 57(4), p.2057 - 2060, 1998/04
Times Cited Count:15 Percentile:63.99(Physics, Nuclear)no abstracts in English
Takada, Hiroshi; *; Yoshizawa, Nobuaki*; Nakahara, Yasuaki
Journal of Nuclear Science and Technology, 31(1), p.80 - 82, 1994/01
Times Cited Count:1 Percentile:26.96(Nuclear Science & Technology)no abstracts in English
Takada, Hiroshi; Nakahara, Yasuaki; ; *; Yoshizawa, Nobuaki*
Proc. of NEA/NSC Specialists Meeting on Intermediate Energy Nuclear Data:Models and Codes, 0, p.121 - 136, 1994/00
no abstracts in English
; ; Kitamura, Toshikatsu; *; ; ;
Genshiryoku Kogyo, 38(4), p.32 - 50, 1992/04
no abstracts in English
Kakuta, Tsunemi; Kitamura, Toshikatsu; Mizushima, Toshihiko; ; *; *; *; *; *
JAERI-M 92-034, 82 Pages, 1992/03
no abstracts in English
; Kitamura, Toshikatsu; Mizushima, Toshihiko; Kakuta, Tsunemi; *; *; *; *; *; *
JAERI-M 91-212, 107 Pages, 1992/01
no abstracts in English
Otsuki, Tsutomu*; Nagame, Yuichiro; Tsukada, Kazuaki*; Shinohara, Nobuo; *; Hashimoto, Kazuyuki; *; Sueki, Keisuke*; ; ; et al.
Physical Review C, 44(4), p.1405 - 1423, 1991/10
Times Cited Count:35 Percentile:86.06(Physics, Nuclear)no abstracts in English
Suwa, Takeshi; *; ; ; ; Hoshi, Michio; Sagawa, Chiaki; Yonezawa, Chushiro; ; ; et al.
Nihon Genshiryoku Gakkai-Shi, 30(11), p.1020 - 1029, 1988/11
Times Cited Count:0 Percentile:1.69(Nuclear Science & Technology)no abstracts in English
; ; ; *
JAERI-M 6351, 52 Pages, 1975/12
no abstracts in English