Silencing of CPD photolyase makes hypersensitive and hypermutable in response to UV-B radiation

Yoshihara, Ryohei; Nakane, Chiyoko*; Sato, Ryohei*; Yasuda, Ai*; Takimoto, Koichi*

Genes and Environment, 30(2), p.53 - 61, 2008/05

https://doi.org/10.3123/jemsge.30.53

We generated a CPD photolyase knock-down in by RNAi to investigate the role of CPD photorepair for protection of plants from solar UV. These knock-down lines exhibited hypersensitivity to UV-B and an increased occurrence of mutation induced by UV-B radiation compared with proficient in CPD photolyase. These results indicate that CPD photoreactivation plays an important role for UV resistance of and suppression of UV-induced mutagenesis.