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Journal Articles

Review of the microdosimetric studies for high-energy charged particle beams using a tissue-equivalent proportional counter

Tsuda, Shuichi; Sato, Tatsuhiko; Ogawa, Tatsuhiko; Sasaki, Shinichi*

JPS Conference Proceedings (Internet), 11, p.060004_1 - 060004_6, 2016/11

Track structure and energy deposition around charged particle beams in microscopic site of a living cell is important information for understanding of biological effects of energetic heavy ion beams. In this work, measurements of lineal energy ($$y$$) distributions for various kinds of ion beams have been performed for the verification of the microdosimetric function that incorporated in the PHITS code. In the international symposium focused on radiation detectors, the wall-less tissue equivalent proportional counter that developed in this study to measure $$y$$ distributions will be introduced, together with a series of data.

Journal Articles

Systematic measurement of lineal energy distributions for proton, He and Si ion beams over a wide energy range using a wall-less tissue equivalent proportional counter

Tsuda, Shuichi; Sato, Tatsuhiko; Takahashi, Fumiaki; Satoh, Daiki; Sasaki, Shinichi*; Namito, Yoshihito*; Iwase, Hiroshi*; Ban, Shuichi*; Takada, Masashi*

Journal of Radiation Research, 53(2), p.264 - 271, 2012/04

 Times Cited Count:14 Percentile:55.96(Biology)

Deposit energy distribution in microscopic site is basic information for understanding of biological effects of energetic heavy ion beams. To estimate RBE, lineal energy, $$y$$, can be an appropriate physical index. In this work, a wall-less tissue equivalent proportional counter has been designed and used for the measurement of $$y$$ distributions, $$y$$$$f$$($$y$$), for 160 MeV H, 150 MeV/u He, 290 MeV/u C, 490 MeV/u Si and 500 MeV/u Ar. Data of $$y$$$$f$$($$y$$) were also obtained in the wide range of LET. The dose-means of $$y$$, $$overline{y}$$$$_{D}$$, were compared with those calculated by the microdosimetric function of PHITS. It is found that the calculated $$y$$$$f$$($$y$$) and $$overline{y}$$$$_{D}$$ agree fairly well with those measured. The values of $$overline{y}$$$$_{D}$$ are larger than those of LET less than $$sim$$10 keV/$$mu$$m because of the discrete energy deposition by delta rays, while the relation is reversed above 10 keV/$$mu$$m. The results indicate that care should be taken in the difference between $$overline{y}$$$$_{D}$$ and LET when the values of RBE of energetic heavy ions are estimated.

Journal Articles

Measurement of lineal energy distribution of heavy ion using wall-less tissue equivalent proportional counter

Tsuda, Shuichi; Sato, Tatsuhiko; Takahashi, Fumiaki; Satoh, Daiki; Sasaki, Shinichi*; Namito, Yoshihito*; Iwase, Hiroshi*; Ban, Shuichi*; Takada, Masashi*

KEK Proceedings 2011-8, p.100 - 108, 2011/12

Deposit energy distribution in microscopic site is basic information for understanding of biological effects of energetic heavy ion beams. To estimate RBE, lineal energy, y, can be an appropriate physical index. In this work, a wall-less tissue equivalent proportional counter has been designed and used for the measurement of y distributions, $$yf(y)$$, for 160 MeV H, 150 MeV/u He and 490 MeV/u Si ion beams. Data of $$yf(y)$$ and the dose-means of $$y$$, $$overline{y}_D$$, were compared with those calculated by the microdosimetric function of PHITS. It is found that the calculated $$yf(y)$$ and $$overline{y}_D$$ agree fairly well with those measured, as well as the already reported result of 290 MeV/u carbon beam.

Journal Articles

Measurement of deposit energy distribution of heavy ions using a wall-less tissue equivalent proportional counter

Tsuda, Shuichi; Sato, Tatsuhiko; Satoh, Daiki; Takahashi, Fumiaki; Sasaki, Shinichi*; Namito, Yoshihito*; Sanami, Toshiya*; Saito, Kiwamu*; Takada, Masashi*

HIMAC-136, p.219 - 220, 2011/11

Measurements of lineal energy distribution were employed using 160 MeV proton and 490 MeV/u Si. The calculated $$yf(y)$$ by PHITS and $$overline{y}_D$$ agree fairly well with those measured. The LET dependence of $$overline{y}_D$$ was obtained from 3 to 300 keV/um in this project.

Journal Articles

Analysis of the effect of structural materials in a wall-less tissue-equivalent proportional counter irradiated by 290 MeV u$$^{-1}$$ carbon beam

Tsuda, Shuichi; Sato, Tatsuhiko; Takahashi, Fumiaki; Satoh, Daiki; Endo, Akira; Sasaki, Shinichi*; Namito, Yoshihito*; Iwase, Hiroshi*; Ban, Shuichi*; Takada, Masashi*

Radiation Protection Dosimetry, 143(2-4), p.450 - 454, 2011/02

 Times Cited Count:5 Percentile:38.79(Environmental Sciences)

A wall-less tissue equivalent proportional counter, wall-less TEPC, has been designed and used for the measurement of the y distributions for energetic heavy ions in order to verify a biological dose calculation model incorporated in the PHITS code. It is found that the dose-mean value of y obtained by the wall-less TEPC is 50 - 60% of the LET of the argon ions in water, since the delta-rays with relatively low y can be measured.

Journal Articles

Measurement of microdosimetric spectra with a wall-less tissue-equivalent proportional counter for 290 MeV/u $$^{12}$$C beam

Tsuda, Shuichi; Sato, Tatsuhiko; Takahashi, Fumiaki; Satoh, Daiki; Endo, Akira; Sasaki, Shinichi*; Namito, Yoshihito*; Iwase, Hiroshi*; Ban, Shuichi*; Takada, Masashi*

Physics in Medicine & Biology, 55(17), p.5089 - 5101, 2010/09

 Times Cited Count:23 Percentile:60.88(Engineering, Biomedical)

The frequency distribution of the lineal energy of 290 MeV/u carbon beam was measured using a wall-less tissue equivalent proportional counter (wall-less TEPC) in a cylindrical volume with simulated diameter 0.72 $$mu$$m in verifying the accuracy of a dose calculation model. The measured lineal energy distribution as well as its dose-mean value agreed fairly well with the corresponding data from microdosimetric calculations using the PHITS code within the experimental uncertainty. It is found that a wall-less TEPC is needed to measure the precise energy deposition spectra of the delta rays produced secondarily by energetic heavy ion beams. The measured data also indicate that more than 11% of the energy escaped from the path of the trajectory of the carbon beam.

Journal Articles

Measurement of deposit energy distribution of heavy ions using a wall-less tissue equivalent proportional counter

Tsuda, Shuichi; Sato, Tatsuhiko; Satoh, Daiki; Takahashi, Fumiaki; Endo, Akira; Sasaki, Shinichi*; Namito, Yoshihito*; Sanami, Toshiya*; Saito, Kiwamu*; Takada, Masashi*

HIMAC-134 (CD-ROM), p.227 - 228, 2010/06

no abstracts in English

Journal Articles

Measurement of lineal energy distribution by a wall-less tissue equivalent proportional counter for heavy ion beams

Tsuda, Shuichi; Sato, Tatsuhiko; Takahashi, Fumiaki; Satoh, Daiki; Endo, Akira; Sasaki, Shinichi*; Namito, Yoshihito*; Iwase, Hiroshi*; Ban, Shuichi*; Takada, Masashi*

KEK Proceedings 2009-12, p.36 - 44, 2010/01

Knowledge of energy deposition at micrometer dimensions along heavy ion tracks is essential to understand the biological effects of radiation. Wall-less tissue equivalent proportional counter (wall-less TEPC) was produced for the purpose of measurement of lineal energy distribution including secondary-produced high-energy electrons, delta-rays. The measurement using the wall-less TEPC was performed at Heavy Ion Medical Accelerator at NIRS, Japan. It is found that lineal energy distributions could be measured for primary carbon beam with energy of 400MeV per nucleon and delta-rays. Detail of the experiment, energy calibration and estimation of delta-rays production will be presented.

Journal Articles

Evaluation of delta-rays production in a wall-less tissue equivalent proportional counter irradiated by energetic heavy ion beams

Tsuda, Shuichi; Sato, Tatsuhiko; Iwase, Hiroshi*; Namito, Yoshihito*; Sasaki, Shinichi*

KEK Proceedings 2009-6, p.90 - 95, 2009/11

Deposit energy distributions of secondary high-energy electrons, delta-rays, have been calculated in a wall/wall-less tissue equivalent proportional counter, TEPC, using Monte Carlo simulation code EGS5. It is found that wall-less TEPCs are indispensable for lineal energy distribution in tissue equivalent gas irradiated by energetic heavy ion beams.

Journal Articles

Measurement of deposit energy distribution of heavy ions using a wall-less tissue equivalent proportional counter

Tsuda, Shuichi; Sato, Tatsuhiko; Satoh, Daiki; Takahashi, Fumiaki; Endo, Akira; Sasaki, Shinichi*; Namito, Yoshihito*; Sanami, Toshiya*; Saito, Kiwamu*; Takada, Masashi*

NIRS-M-226, HIMAC-132, p.264 - 265, 2009/06

A wall-less tissue equivalent proportional counter was designed and applied to measuring deposit energy distribution of heavy ion beams, including the contribution of delta-rays produced along heavy ion tracks. Lineal energy distributions were obtained for 400 MeV/u carbon and 490 MeV/u silicon beams.

Journal Articles

Progress in R&D efforts on the energy recovery linac in Japan

Sakanaka, Shogo*; Ago, Tomonori*; Enomoto, Atsushi*; Fukuda, Shigeki*; Furukawa, Kazuro*; Furuya, Takaaki*; Haga, Kaiichi*; Harada, Kentaro*; Hiramatsu, Shigenori*; Honda, Toru*; et al.

Proceedings of 11th European Particle Accelerator Conference (EPAC '08) (CD-ROM), p.205 - 207, 2008/06

Future synchrotron light sources based on the energy-recovery linacs (ERLs) are expected to be capable of producing super-brilliant and/or ultra-short pulses of synchrotron radiation. Our Japanese collaboration team is making efforts for realizing an ERL-based hard X-ray source. We report recent progress in our R&D efforts.

Journal Articles

Radiation safety design for the J-PARC project

Nakashima, Hiroshi; Nakane, Yoshihiro; Masukawa, Fumihiro; Matsuda, Norihiro; Oguri, Tomomi*; Nakano, Hideo*; Sasamoto, Nobuo*; Shibata, Tokushi*; Suzuki, Takenori*; Miura, Taichi*; et al.

Radiation Protection Dosimetry, 115(1-4), p.564 - 568, 2005/12

 Times Cited Count:8 Percentile:49.23(Environmental Sciences)

The High Intensity Proton Accelerator Project, named as J-PARC, is in progress, aiming at studies on the latest basic science and the advancing nuclear technology. In the project, the high-energy proton accelerator complex of the world highest intensity is under construction. In order to establish a reasonable shielding design, both simplified and detailed design methods were used in the shielding design of J-PARC. This paper reviews the present status of the radiation safety design study for J-PARC.

Journal Articles

Gain saturation of nickel-like silver and tin X-ray lasers by use of a tabletop pumping laser system

Kawachi, Tetsuya; Kado, Masataka; Tanaka, Momoko; Sasaki, Akira; Hasegawa, Noboru; Kilpio, A.*; Namba, Shinichi; Nagashima, Keisuke; Lu, P.; Takahashi, Kenjiro; et al.

Physical Review A, 66(3), p.033815_1 - 033815_7, 2002/09

 Times Cited Count:85 Percentile:93.06(Optics)

A silver and tin slab targets were irradiated by a line-focused CPA glass laser light. In this experiment, the laser pulses consisted of two pulses with 4 ps duration, separated by 1.2 ns. Strong amplification in the nickel-like silver and tin x-ray lasers at the wavelengths of 13.9nm and 12.0nm was demonstrated with a pumping energy of 12 J and 14 J, respectively, and gain-saturation behaviors could be seen. A hydro-dynamics simulation coupled with a collisional-radiative model was performed under the present experimental condition, and the calculated result was compared with the experimental results.

Journal Articles

X-ray laser research at Advanced Photon Research Center of JAERI, Kansai

Kado, Masataka; Kawachi, Tetsuya; Tanaka, Momoko; Hasegawa, Noboru; Takahashi, Kenjiro; Namba, Shinichi; Sukegawa, Kota*; Sasaki, Akira; Lu, P.; Tang, H.; et al.

Soft X-Ray Lasers and Applications IV (Proceedings of SPIE Vol.4505), p.54 - 61, 2001/12

no abstracts in English

JAEA Reports

None

*; *; Tsunoda, Naomi; *; ; Sasaki, Noriaki; *; *

PNC TN841 76-48, , 1976/12

PNC-TN841-76-48.pdf:1.09MB

no abstracts in English

Oral presentation

Radiation safety at J-PARC

Nakashima, Hiroshi; Shibata, Tokushi; Sawahata, Kei; Miyamoto, Yukihiro; Nakane, Yoshihiro; Masukawa, Fumihiro; Seki, Kazunari; Sato, Koichi; Oguri, Tomomi*; Hirayama, Hideo*; et al.

no journal, , 

Aiming at studies on the latest basic science and the advancing nuclear technology, the J-PARC (Japan Proton Accelerator Research Complex) project is in progress, and the high-energy proton accelerator complex of the world highest intensity is under construction. Because of its very high beam power and its energy as well as the large-scale accelerator complex, we have encountered some difficult radiation problems in the radiation safety design. This paper reviews the radiation safety policy and methods for the design to overcome the problems on the radiation safety and the status of the radiation safety estimation for licensing of J-PARC.

Oral presentation

Design and performance tests of a wall-less tissue equivalent proportional counter for microdosimetry

Tsuda, Shuichi; Sato, Tatsuhiko; Endo, Akira; Satoh, Daiki; Takahashi, Fumiaki; Sasaki, Shinichi*; Namito, Yoshihito*; Iwase, Hiroshi*; Ban, Shuichi*; Takada, Masashi*

no journal, , 

Energy deposition of secondary charged particles produced in tissue irradiated by heavy ion beams is important information in order to evaluate biological effects of cells. In this study a wall-less tissue equivalent proportional counter (wall-less TEPC) was designed and its performance tests have been carried out using checking sources such as a Cm-244 $$alpha$$ source. It is found that the wall-less TEPC can be used in measurements of energy deposition in tissue irradiated by heavy ion beams, based on measurements of gas gain in tissue equivalent gas and lineal energy distributions.

Oral presentation

Measurement of lineal energy distributions by a wall-less tissue equivalent proportional counter using 400 MeV/u carbon beam

Tsuda, Shuichi; Sato, Tatsuhiko; Takahashi, Fumiaki; Satoh, Daiki; Endo, Akira; Sasaki, Shinichi*; Namito, Yoshihito*; Iwase, Hiroshi*; Ban, Shuichi*; Takada, Masashi*

no journal, , 

Knowledge of energy deposition at micrometer dimensions along heavy ion tracks is essential to understand the biological effects of radiation. Wall-less tissue equivalent proportional counter (TEPC) was produced for the purpose of measurement of lineal energy distribution of delta-rays. The measurement using the TEPC was performed at Heavy Ion Medical Accelerator at NIRS, Japan. It is found that lineal energy distributions could be measured for primary carbon beam with energy of 400MeV per nucleon and delta-rays. Detail of the experiment, energy calibration and estimation of delta-rays production will be presented.

Oral presentation

Measurement of lineal energy distribution of 290 MeV/u carbon beam using a wall-less tissue equivalent proportional counter

Tsuda, Shuichi; Sato, Tatsuhiko; Satoh, Daiki; Takahashi, Fumiaki; Sasaki, Shinichi*; Namito, Yoshihito*; Iwase, Hiroshi*; Ban, Shuichi*; Takada, Masashi*

no journal, , 

The frequency distribution of the lineal energy, y, of 290 MeV/u carbon beam was measured to obtain the dosed-mean of y and compare it with the linear energy transfer, LET. In the experiment a wall-less tissue equivalent proportional counter, TEPC, in a cylindrical volume with simulated diameter 0.72 micrometer was used. The measured frequency distribution of y as well as its dose-mean value agrees fairly well with the corresponding data from microdosimetric calculations using the PHITS code within the experimental uncertainty. The ratio of the measured dose-mean lineal energy to the LET of the 290 MeV/u carbon beam is 0.73, which is much smaller than the corresponding data obtained by a wall TEPC. This result demonstrates that a wall-less TEPC is necessary to precisely measure the dose-mean of y for energetic heavy ion beams.

Oral presentation

Measurements of lineal energy distributions of various energetic heavy ion beams using a wall-less tissue equivalent proportional counter

Tsuda, Shuichi; Sato, Tatsuhiko; Takahashi, Fumiaki; Satoh, Daiki; Sasaki, Shinichi*; Namito, Yoshihito*; Iwase, Hiroshi*; Ban, Shuichi*; Takada, Masashi*

no journal, , 

Deposit energy distribution in microscopic site is basic information for understanding of biological effects of energetic heavy ion beams. To estimate RBE, lineal energy, y, can be an appropriate physical index. In this work, a wall-less tissue equivalent proportional counter has been designed and used for the measurement of y distributions, yf(y), for 160 MeV H, 150 MeV/u He, 290 MeV/u C, 490 MeV/u Si and 500 MeV/u Ar. Data of yf(y) were also obtained in the wide range of LET. The dose-means of y, yD, were compared with those calculated by the microdosimetric function of PHITS. It is found that the calculated yf(y) and yD agree fairly well with those measured. The values of yD are larger than those of LET less than 10 keV/um because of the discrete energy deposition by delta rays, while the relation is reversed above 10 keV/um. The results indicate that care should be taken in the difference between yD and LET when the values of RBE of energetic heavy ions are estimated.

22 (Records 1-20 displayed on this page)