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Journal Articles

PSTEP: Project for solar-terrestrial environment prediction

Kusano, Kanya*; Ichimoto, Kiyoshi*; Ishii, Mamoru*; Miyoshi, Yoshizumi*; Yoden, Shigeo*; Akiyoshi, Hideharu*; Asai, Ayumi*; Ebihara, Yusuke*; Fujiwara, Hitoshi*; Goto, Tadanori*; et al.

Earth, Planets and Space (Internet), 73(1), p.159_1 - 159_29, 2021/12

 Times Cited Count:6 Percentile:49.29(Geosciences, Multidisciplinary)

The PSTEP is a nationwide research collaboration in Japan and was conducted from April 2015 to March 2020, supported by a Grant-in-Aid for Scientific Research on Innovative Areas from the Ministry of Education, Culture, Sports, Science and Technology of Japan. It has made a significant progress in space weather research and operational forecasts, publishing over 500 refereed journal papers and organizing four international symposiums, various workshops and seminars, and summer school for graduate students at Rikubetsu in 2017. This paper is a summary report of the PSTEP and describes the major research achievements it produced.

Journal Articles

Transient ionization of the mesosphere during auroral breakup; Arase satellite and ground-based conjugate observations at Syowa Station

Kataoka, Ryuho*; Nishiyama, Takanori*; Tanaka, Yoshimasa*; Kadokura, Akira*; Uchida, Herbert Akihito*; Ebihara, Yusuke*; Ejiri, Mitsumu*; Tomikawa, Yoshihiro*; Tsutsumi, Masaki*; Sato, Kaoru*; et al.

Earth, Planets and Space (Internet), 71(1), p.9_1 - 9_10, 2019/12

 Times Cited Count:8 Percentile:39.55(Geosciences, Multidisciplinary)

Transient ionization of the mesosphere was detected at around 65 km altitude during the isolated auroral expansion occurred at 2221-2226 UT on June 30, 2017. A general-purpose Monte Carlo particle transport code PHITS suggested that significant ionization is possible in the middle atmosphere due to auroral X-rays from the auroral electrons of $$<$$10 keV.

Journal Articles

Corrigendum: Beam range estimation by measuring bremsstrahlung (2012 Phys. Med. Biol. 57 2843)

Yamaguchi, Mitsutaka; Torikai, Kota*; Kawachi, Naoki; Shimada, Hirofumi*; Sato, Takahiro; Nagao, Yuto; Fujimaki, Shu; Kokubun, Motohide*; Watanabe, Shin*; Takahashi, Tadayuki*; et al.

Physics in Medicine & Biology, 61(9), p.3638 - 3644, 2016/05

 Times Cited Count:9 Percentile:100(Engineering, Biomedical)

no abstracts in English

Journal Articles

Detection of a gas region in a human body across a therapeutic carbon beam by measuring low-energy photons

Yamaguchi, Mitsutaka; Nagao, Yuto; Kawachi, Naoki; Sato, Takahiro; Fujimaki, Shu; Kamiya, Tomihiro; Torikai, Kota*; Shimada, Hirofumi*; Sugai, Hiroyuki*; Sakai, Makoto*; et al.

International Journal of PIXE, 26(1&2), p.61 - 72, 2016/00

no abstracts in English

Journal Articles

Three-dimensional and multienergy $$gamma$$-ray simultaneous imaging by using a Si/CdTe Compton camera

Suzuki, Yoshiyuki*; Yamaguchi, Mitsutaka; Odaka, Hirokazu*; Shimada, Hirofumi*; Yoshida, Yukari*; Torikai, Kota*; Sato, Takahiro; Arakawa, Kazuo*; Kawachi, Naoki; Watanabe, Shigeki; et al.

Radiology, 267(3), p.941 - 947, 2013/06

 Times Cited Count:23 Percentile:64.83(Radiology, Nuclear Medicine & Medical Imaging)

Journal Articles

A New method for monitoring beam range by measuring low energy photons

Yamaguchi, Mitsutaka; Torikai, Kota*; Kawachi, Naoki; Shimada, Hirofumi*; Sato, Takahiro; Nagao, Yuto; Fujimaki, Shu; Kokubun, Motohide*; Watanabe, Shin*; Takahashi, Tadayuki*; et al.

Proceedings of 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC), 2 Pages, 2013/00

Journal Articles

Beam range estimation by measuring bremsstrahlung

Yamaguchi, Mitsutaka; Torikai, Kota*; Kawachi, Naoki; Shimada, Hirofumi*; Sato, Takahiro; Nagao, Yuto; Fujimaki, Shu; Kokubun, Motohide*; Watanabe, Shin*; Takahashi, Tadayuki*; et al.

Physics in Medicine & Biology, 57(10), p.2843 - 2856, 2012/05

 Times Cited Count:41 Percentile:79.84(Engineering, Biomedical)

Journal Articles

Three-dimensional imaging test for a head module of a Si/CdTe Compton camera for medical application

Yamaguchi, Mitsutaka; Kawachi, Naoki; Kamiya, Tomihiro; Sato, Takahiro; Suzui, Nobuo; Fujimaki, Shu; Odaka, Hirokazu*; Ishikawa, Shinnosuke*; Kokubun, Motohide*; Watanabe, Shin*; et al.

JAEA-Review 2011-043, JAEA Takasaki Annual Report 2010, P. 145, 2012/01

no abstracts in English

Journal Articles

Analysis on the co-localization of asbestos bodies and Fas or CD163 expression in asbestos lung tissue by in-air micro-PIXE

Dobashi, Kunio*; Shimizu, Yasuo*; Matsuzaki, Shinichi*; Nagamine, Takeaki*; Sato, Takahiro; Okubo, Takeru; Yokoyama, Akihito; Ishii, Yasuyuki; Kamiya, Tomihiro; Arakawa, Kazuo*; et al.

JAEA-Review 2011-043, JAEA Takasaki Annual Report 2010, P. 87, 2012/01

Journal Articles

Quantitative analysis of cisplatin sensitivity of human esophageal squamous cancer cell lines using in-air micro-PIXE

Tanaka, Naritake*; Kimura, Hitoshi*; Faried, A.*; Sakai, Makoto*; Sano, Takaaki*; Inose, Takanori*; Soda, Makoto*; Okada, Koji*; Nakajima, Masanobu*; Miyazaki, Tatsuya*; et al.

Cancer Science, 101(6), p.1487 - 1492, 2010/06

 Times Cited Count:12 Percentile:31.68(Oncology)

We examined the intracellular localization of cisplatin, a key chemotherapeutic agent, in esophageal cancer cell lines and determined their sensitivity to cisplatin using in-air micro-PIXE. Two human esophageal squamous cell carcinoma (ESCC) cell lines, TE-2 and TE-13, were examined for their response to cisplatin using MTT assay, flow cytometry and DNA fragmentation assays. Real-time reverse transcription-polymerase chain reaction was also used to evaluate the mRNA expression of multidrug resistance protein 2 (MRP2) in both cell lines. Platinum localizations of intracellular and intranuclear were measured using in-air micro-PIXE. TE-2 cells were more sensitive to cisplatin than TE-13 cells. The results of this study suggest that in-air micro-PIXE could be a useful quantitative method for evaluating the cisplatin sensitivity of individual cells. Finally, we speculate that MRP2 in the cell membrane may play an important role in regulating cisplatin sensitivity of ESCC cells.

Journal Articles

Analysis on the Co-localization of asbestos bodies and Fas or CD163 expression in asbestos lung tissue by in-air micro-PIXE

Matsuzaki, Shinichi*; Shimizu, Yasuo*; Dobashi, Kunio*; Nagamine, Takeaki*; Sato, Takahiro; Okubo, Takeru; Yokoyama, Akihito; Ishii, Yasuyuki; Kamiya, Tomihiro; Arakawa, Kazuo*; et al.

International Journal of Immunopathology and Pharmacology, 23(1), p.1 - 11, 2010/01

Journal Articles

Basic characteristics of a newly developed Si/CdTe Compton camera for medical imaging

Kawachi, Naoki; Watanabe, Shigeki; Sato, Takahiro; Arakawa, Kazuo; Takeda, Shinichiro*; Ishikawa, Shinnosuke*; Aono, Hiroyuki*; Watanabe, Shin*; Yamaguchi, Mitsutaka*; Takahashi, Tadayuki*; et al.

2008 IEEE Nuclear Science Symposium Conference Record (CD-ROM), p.1540 - 1543, 2008/10

Journal Articles

Design of pencil beam formation system for high-accuracy carbon-ion microsurgery

Arakawa, Kazuo; Oikawa, Masakazu*; Shimada, Hirofumi*; Kamiya, Tomihiro; Nakano, Takashi*; Yusa, Ken*; Kato, Hiroyuki*; Sato, Takahiro; Agematsu, Takashi; Kashiwagi, Hirotsugu; et al.

Proceedings of 4th Annual Meeting of Particle Accelerator Society of Japan and 32nd Linear Accelerator Meeting in Japan (CD-ROM), p.279 - 281, 2007/00

no abstracts in English

Journal Articles

Interferon$$beta$$-induced changes in metallothionein expression and subcellular distribution of zinc in HepG2 cells

Nagamine, Takeaki*; Kusakabe, Takahiko*; Takada, Hisashi*; Nakazato, Kyomi*; Sakai, Takuro; Oikawa, Masakazu*; Sato, Takahiro; Arakawa, Kazuo

Cytokine, 34(5-6), p.312 - 319, 2006/06

 Times Cited Count:8 Percentile:16.47(Biochemistry & Molecular Biology)

no abstracts in English

JAEA Reports

A Study of the criticality safety design for the metal fuel recycle system, 2

Nakabayashi, Hiroki; Kurisaka, Kenichi; Sato, Koji; Niwa, Hajime; Aoki, Kazuo*

JAEA-Technology 2006-027, 119 Pages, 2006/03

JAEA-Technology-2006-027.pdf:9.02MB

This report describes a study about the criticality safety design for the large-scale electrorefiner, which is designed in the activities of "The Design Study of Metal Fuel Recycle System (2002)", under the collaboration with Central Research Institute of Electric Power Industry, and the continuation of "A Study of the Criticality Safety Design for the Metal Fuel Recycle System", which was published at September 2003. The report includes a detail design and quantitative criticality parameter limits based on "the mass control supported with chemical form control" concept which is proposed in "A Study of the Criticality Safety Design for the Metal Fuel Recycle System". Furthermore procedures to determine these limits are presented in the report. Next we studied contingencies anticipated under the critical control and executed quantitative criticality safety analyses of models based on these abnormal conditions. The analytical result shows adequate safety margins are existed in the criticality safety design even if many of these contingencies could occur. Moreover we propose a concept of material transfer and production control system, we call it as "Operation by wire", which all equipment and handling machines are electrified and the control system provides completely automated process control and operation. The control system eliminates human errors and violations like over batching error or transfer error in the commercial scale metal fuel recycle system with complicated operation procedures.

Journal Articles

Research of disease onset mechanism by determining the distribution of intracellular trace elements using an in-air micro-PIXE analyzer system

Nakano, Takashi*; Arakawa, Kazuo; Sakurai, Hideyuki*; Hasegawa, Masatoshi*; Yuasa, Kazuhisa*; Saito, Etsuko*; Takagi, Hitoshi*; Nagamine, Takeaki*; Kusakabe, Takahiko*; Takada, Hisashi*; et al.

International Journal of PIXE, 16(1&2), p.69 - 76, 2006/00

A new program was started out to create a new medical scientific field, which is consisting of radiation oncology and nuclear medicine, utilizing the advanced accelerator and ion beam technology. An in-air micro-PIXE analyzer system, which is among the most important technical basis of the program, was upgraded to improve accuracy of elemental mapping for samples having thickness variation in a scope of microbeam scanning. In the program, on the other hand, in order to approach important bio-medical problems on cancer, intracellular dynamics of the trace elements according to mechanism of development of diseases were studied using this system. This paper outlines this program and shows the system upgraded, and results of preliminary studied about the problems.

Journal Articles

Angular distribution measurements of photo-neutron yields produced by 2.0 GeV electrons incident on thick targets

Lee, H.-S.*; Ban, Shuichi*; Sanami, Toshiya*; Takahashi, Kazutoshi*; Sato, Tatsuhiko; Shin, Kazuo*; Chung, C. W.*

Radiation Protection Dosimetry, 116(1-4), p.653 - 657, 2005/12

 Times Cited Count:5 Percentile:35.66(Environmental Sciences)

A study of differential photo-neutron yields by irradiation with 2 GeV electrons has been carried out. In this extension of a previous study in which measurements were made at an angle of 90 degrees. Relative to incident electrons, the differential photoneutron yield was obtained at two other angles, 48 and 140 degrees, to study its angular characteristics. Photo-neutron spectra were measured using a pulsed beam time-of-flight method and a BC418 plastic scintillator. The reliable range of neutron energy measurement was 8-250 MeV. The neutron spectra were measured for 10 Xo-thick Cu, Sn, W and Pb targets. The angular distribution characteristics, together with the previous results for 90, are presented in the study. The experimental results are compared with Monte Carlo calculation results. The yields predicted by MCNPX 2.5 tend to underestimate the measured ones. The same trend holds for the comparison results using the EGS4 and PICA3 codes.

Journal Articles

Radon concentration dependence of alpha radioactivity measurement using ionized air transportation

Naito, Susumu*; Sano, Akira*; Izumi, Mikio*; Noda, Etsuo*; Hayashi, Kazuo*; Sato, Mitsuyoshi*; Suto, Osamu; Miyamoto, Yasuaki; Kondo, Shinichi*; Iinuma, Koichi*; et al.

Nuclear Science Symposium Conference Record, 2005 IEEE, Vol.1, p.495 - 499, 2005/10

An alpha radioactivity monitor (alpha-clearance monitor) is being developed to measure alpha radioactivity of uranium contaminated waste with large and complex surfaces. It uses an alpha radioactivity measurement method by collecting the air ionized by alpha particles using an air stream and by measuring its ion current. One of the major problems of the alpha-clearance monitor is the background ion current mainly by radon in atmosphere ($$sim$$700 fA), which is much larger than ion current of an alpha particle (several fA). It strongly influences on the detection limit of alpha radioactivity. In order to improve the detection limit, we developed a method to monitor the radon concentration inside the monitor without the additional radon detector. In addition, the influencing factors on the detection limit: ion mobility and ion recombination coefficient were measured and evaluated on various environmental conditions (temperature, humidity and aerosol density).

Journal Articles

Analysis of intracellular distribution of boron and gadolinium in 9L sarcoma cells using a single-ended accelerator (Micro PIXE)

Endo, Kiyoshi*; Shibata, Yasushi*; Yoshida, Fumiyo*; Nakai, Kei*; Yamamoto, Tetsuya*; Matsumura, Akira*; Ishii, Keizo*; Sakai, Takuro; Sato, Takahiro; Oikawa, Masakazu*; et al.

Proceedings of 11th World Congress on Neutron Capture Therapy (ISNCT-11) (CD-ROM), 2 Pages, 2004/10

Micro PIXE, which is installed in a single end accelerator in JAERI, was used for quantitative analysis of boron and gadolinium distribution in a cell level. The micro beam of 1 $$mu$$m diameter is possible to observe the distribution. In the adjustment procedure of the sample, first is a fix of mylar film by using a glass ring and a bite ring of 2cm diameter. Next the 9L cells were scattered on the washed film, and is cultivated on 37$$^{circ}$$C in medium until they form the mono-layer. After the Gd-BOPTA was added, it incubates for the 24-72 hour on 37$$^{circ}$$C. The film is washed in the THAM liquid, and is directly put on liquid nitrogen. A vacuum drying for 24 hours is conducted in order to fix a film on holder. It is important to uniformly fix the cell in distribution analysis in the cell using Micro PIXE. In recent result, it became possible that the distribution of P, S, Gd, etc. was analyzed. But we could not distinguish whether K and Gd exist in the cell or whether it exists around the cell. It was indicated that these elements was leaked by the reason of cell breaking or other on the cytoplasm.

Journal Articles

Progress in physics and technology developments for the modification of JT-60

Tamai, Hiroshi; Matsukawa, Makoto; Kurita, Genichi; Hayashi, Nobuhiko; Urata, Kazuhiro*; Miura, Yushi; Kizu, Kaname; Tsuchiya, Katsuhiko; Morioka, Atsuhiko; Kudo, Yusuke; et al.

Plasma Science and Technology, 6(1), p.2141 - 2150, 2004/02

 Times Cited Count:2 Percentile:6.49(Physics, Fluids & Plasmas)

The dominant issue for the the modification program of JT-60 (JT-60SC) is to demonstrate the steady state reactor relevant plasma operation. Physics design on plasma parameters, operation scenarios, and the plasma control method are investigated for the achievement of high-$$beta$$. Engineering design and the R&D on the superconducting magnet coils, radiation shield, and vacuum vessel are performed. Recent progress in such physics and technology developments is presented.

73 (Records 1-20 displayed on this page)