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Journal Articles

Measurements of electron-induced neutrons as a tool for determination of electron temperature of fast electrons in the task of optimization laser-produced plasma ions acceleration

Sakaki, Hironao; Nishiuchi, Mamiko; Maeda, Shota; Sagisaka, Akito; Pirozhkov, A. S.; Pikuz, T.; Faenov, A.*; Ogura, Koichi; Fukami, Tomoyo; Matsukawa, Kenya*; et al.

Review of Scientific Instruments, 85(2), p.02A705_1 - 02A705_4, 2014/02

 Times Cited Count:2 Percentile:11.15(Instruments & Instrumentation)

High intensity laser-plasma interaction has attracted considerable interest for a number of years. The laser-plasma interaction is accompanied by generation of various charged particle beams. Results of simultaneous novel measurements of electron-induced photonuclear neutrons (photoneutron), which are a diagnostic of the laser-plasma interaction, are proposed to use for optimization of the laser-plasma ion generation. The proposed method is demonstrated by the laser irradiation with the intensity os 1$$times$$10$$^{21}$$ W/cm$$^{2}$$ on the metal foil target. The photoneutrons are measured by using NE213 liquid scintillation detectors. Heavy-ion signal is registered with the CR39 track detector simultaneously. The measured signals of the electron-induced photoneutrons are well reproduced by using the Particle and Heavy Ion Transport code System (PHITS). The results obtained provide useful approach for analyzing the various laser based ion beams.

Journal Articles

Measurement of DNA double-strand break yield in human cancer cells by high-current, short-duration bunches of laser-accelerated protons

Yogo, Akifumi; Sato, Katsutoshi; Nishikino, Masaharu; Maeda, Takuya*; Sakaki, Hironao; Hori, Toshihiko*; Ogura, Koichi; Nishiuchi, Mamiko; Teshima, Teruki*; Nishimura, Hiroaki*; et al.

Japanese Journal of Applied Physics, 50(10), p.106401_1 - 106401_7, 2011/10

 Times Cited Count:8 Percentile:34.56(Physics, Applied)

Journal Articles

Development of laser-driven quasi-monoenergetic proton beam line for radiobiology

Yogo, Akifumi; Maeda, Takuya; Hori, Toshihiko; Sakaki, Hironao; Ogura, Koichi; Nishiuchi, Mamiko; Sagisaka, Akito; Bolton, P.; Murakami, Masao*; Kawanishi, Shunichi; et al.

Nuclear Instruments and Methods in Physics Research A, 653(1), p.189 - 192, 2011/10

 Times Cited Count:9 Percentile:56.9(Instruments & Instrumentation)

Journal Articles

Radiobiology with laser-accelerated quasi-monoenergetic proton beams

Yogo, Akifumi; Maeda, Takuya*; Hori, Toshihiko*; Sakaki, Hironao; Ogura, Koichi; Nishiuchi, Mamiko; Sagisaka, Akito; Bolton, P.; Murakami, Masao*; Kawanishi, Shunichi*; et al.

Proceedings of SPIE Europe Optics + Optoelectronics 2011, Vol.8079, 8 Pages, 2011/04

Journal Articles

Measurement of relative biological effectiveness of protons in human cancer cells using a laser-driven quasimonoenergetic proton beamline

Yogo, Akifumi; Maeda, Takuya; Hori, Toshihiko; Sakaki, Hironao; Ogura, Koichi; Nishiuchi, Mamiko; Sagisaka, Akito; Kiriyama, Hiromitsu; Okada, Hajime; Kanazawa, Shuhei; et al.

Applied Physics Letters, 98(5), p.053701_1 - 053701_3, 2011/02

 Times Cited Count:98 Percentile:94.19(Physics, Applied)

Journal Articles

Test beam-line for laser-driven proton therapy

Sakaki, Hironao; Nishiuchi, Mamiko; Hori, Toshihiko; Bolton, P.; Yogo, Akifumi; Ogura, Koichi; Sagisaka, Akito; Pirozhkov, A. S.; Orimo, Satoshi; Kondo, Kiminori; et al.

Proceedings of 7th Annual Meeting of Particle Accelerator Society of Japan (DVD-ROM), p.312 - 315, 2010/08

The beam transport test is carried out through the test beam line of the laser-driven proton accelerator which consists of the phase rotation cavity, PMQ, and bending magnet. The laser system used is J-KAREN at JAEA. The final transmitted bunch duration and transverse profile are well predicted by the PARMILA particle transport code by assuming relatively low initial current of the proton beam. The most probable explanation for this is the space charge neutralization by the laser-plasma-electrons.

Journal Articles

Measured and simulated transport of 1.9 MeV laser-accelerated proton bunches through an integrated test beam line at 1 Hz

Nishiuchi, Mamiko; Sakaki, Hironao; Hori, Toshihiko; Bolton, P.; Ogura, Koichi; Sagisaka, Akito; Yogo, Akifumi; Mori, Michiaki; Orimo, Satoshi; Pirozhkov, A. S.; et al.

Physical Review Special Topics; Accelerators and Beams, 13(7), p.071304_1 - 071304_7, 2010/07

 Times Cited Count:25 Percentile:79.33(Physics, Nuclear)

A laser-driven repetition-rated 1.9 MeV proton beam line composed of permanent quadrupole magnets (PMQs), a radio frequency (rf) phase rotation cavity, and a tunable monochromator is developed to evaluate and to test the simulation of laser-accelerated proton beam transport through an integrated system for the first time. In addition, the proton spectral modulation and focusing behavior of the rf phase rotationcavity device is monitored with input from a PMQ triplet. In the 1.9 MeV region we observe very weakproton defocusing by the phase rotation cavity. The final transmitted bunch duration and transverse profile are well predicted by the PARMILA particle transport code. The transmitted proton beam duration of 6 ns corresponds to an energy spread near 5% for which the transport efficiency is simulated to be 10%. The predictive capability of PARMILA suggests that it can be useful in the design of future higher energy transport beam lines as part of an integrated laser-driven ion accelerator system.

Journal Articles

Laser-driven proton accelerator for medical application

Nishiuchi, Mamiko; Sakaki, Hironao; Hori, Toshihiko; Bolton, P.; Ogura, Koichi; Sagisaka, Akito; Yogo, Akifumi; Mori, Michiaki; Orimo, Satoshi; Pirozhkov, A. S.; et al.

Proceedings of 1st International Particle Accelerator Conference (IPAC '10) (Internet), p.88 - 90, 2010/05

The concept of a compact ion particle accelerator has become attractive in view of recent progress in laser-driven ion acceleration. We report here the recent progress in the laser-driven proton beam transport at the Photo Medical Research Center (PMRC) at JAEA, which is established to address the challenge of laser-driven ion accelerator development for ion beam cancer therapy.

Journal Articles

Hydrogen and hydration in proteins

Niimura, Nobuo; Chatake, Toshiyuki; Kurihara, Kazuo; Maeda, Mitsuru

Cell Biochemistry and Biophysics, 40(3), p.351 - 369, 2004/06

 Times Cited Count:24 Percentile:25.25(Biochemistry & Molecular Biology)

Neutron diffraction provides an experimental method of directly locating hydrogen atoms in proteins. High resolution neutron diffractometers dedicated to biological macromolecules (BIX-type diffractometer) have been constructed at the Japan Atomic Energy Research Institute (JAERI) and they have been used in the 1.5 AA -resolution crystal structure analyses of several proteins.

Journal Articles

Transport model of boundary plasma and evaluation of transport coefficients

Uehara, Kazuya; Maeda, Mitsuru; Tsushima, Akira*; Amemiya, Hiroshi*

Journal of the Physical Society of Japan, 72(1), p.94 - 100, 2003/01

 Times Cited Count:2 Percentile:21.39(Physics, Multidisciplinary)

no abstracts in English

Journal Articles

Evaluation of particle and thermal diffusivities in the scrape-off layer plasma in JFT-2M tokamak

Uehara, Kazuya; Maeda, Mitsuru; Tsushima, Akira*; Amemiya, Hiroshi*

Contributions to Plasma Physics (CD-ROM), 42(2-4), p.384 - 388, 2002/04

no abstracts in English

Journal Articles

Neutron crystallography of hen egg-white lysozyme at pH4.9

Maeda, Mitsuru; Fujiwara, Satoru; Yonezawa, Yasushige*; Niimura, Nobuo

Journal of the Physical Society of Japan, Vol.70, Supplement A, p.403 - 405, 2001/05

no abstracts in English

Journal Articles

Measuring method for Mach number in tokamak edge plasma using probes

*; Uehara, Kazuya; *

Japanese Journal of Applied Physics, Part 1, 38(5A), p.2971 - 2972, 1999/05

 Times Cited Count:4 Percentile:23.76(Physics, Applied)

no abstracts in English

Journal Articles

Simultaneous measurements of plasma flow and ion temperature using the asymmetric double probe

*; Uehara, Kazuya; *

Japanese Journal of Applied Physics, Part 1, 36(11), p.6992 - 6993, 1997/11

 Times Cited Count:6 Percentile:36.76(Physics, Applied)

no abstracts in English

Journal Articles

Measurement of the plasma flow using the asymmetric double probe in the JFT-2M tokamak

*; Uehara, Kazuya; *

Proc. of 24th European Physical Society Conf. on Controlled Fusion and Plasma Physics, 21A, p.709 - 712, 1997/00

no abstracts in English

Oral presentation

Towards the laser-driven proton accelerator for cancer therapy; Benchmark test of the PARMILA code at the transport and irradiation test beam line

Nishiuchi, Mamiko; Sakaki, Hironao; Hori, Toshihiko; Bolton, P.; Ogura, Koichi; Yogo, Akifumi; Pirozhkov, A. S.; Sagisaka, Akito; Orimo, Satoshi; Mori, Michiaki; et al.

no journal, , 

no abstracts in English

Oral presentation

Radiobiological effects by the irradiation of laser-accelerated proton beams

Yogo, Akifumi; Nishiuchi, Mamiko; Sakaki, Hironao; Hori, Toshihiko; Sato, Katsutoshi; Nishikino, Masaharu; Maeda, Takuya; Mori, Michiaki; Ogura, Koichi; Orimo, Satoshi; et al.

no journal, , 

no abstracts in English

Oral presentation

Measurements of RBE for DNA double-strand break induction by laser-accelerated proton beams

Yogo, Akifumi; Sato, Katsutoshi; Nishikino, Masaharu; Maeda, Takuya; Nishiuchi, Mamiko; Sakaki, Hironao; Hori, Toshihiko; Mori, Michiaki; Ogura, Koichi; Orimo, Satoshi; et al.

no journal, , 

no abstracts in English

Oral presentation

Prototype of beam transport line for laser-driven proton therapy

Sakaki, Hironao; Nishiuchi, Mamiko; Hori, Toshihiko; Kondo, Kiminori; Ogura, Koichi; Yogo, Akifumi; Sagisaka, Akito; Orimo, Satoshi; Mori, Michiaki; Tampo, Motonobu; et al.

no journal, , 

We constructed prototype transportation system of the laser driven 2.0MeV by using nuclear power mechanism J-KAREN laser, and we measured and analyzed this beam line.

Oral presentation

The Integrated laser-driven ion accelerator system; Concept and requirements for laser-driven ion beam radiotherapy

Bolton, P.; Abe, Mitsuyuki*; Akagi, Takashi*; Nuesslin, F.*; Hori, Toshihiko; Iwashita, Yoshihisa*; Kawanishi, Shunichi; Kondo, Kiminori; Maeda, Takuya; Molls, M.*; et al.

no journal, , 

43 (Records 1-20 displayed on this page)