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Journal Articles

Clinical significance of L-type amino acid transporter 1 expression as a prognostic marker and potential of new targeting therapy in biliary tract cancer

Kaira, Kyoichi*; Sunose, Yutaka*; Ohshima, Yasuhiro; Ishioka, Noriko; Arakawa, Kazuhisa*; Ogawa, Tetsushi*; Sunaga, Noriaki*; Shimizu, Kimihiro*; Tominaga, Hideyuki*; Oriuchi, Noboru*; et al.

BMC Cancer, 13, p.482_1 - 482_12, 2013/10

 Times Cited Count:74 Percentile:88.89(Oncology)

Journal Articles

Mechanical properties of full austenitic welding joint at cryogenic temperature for the ITER toroidal field coil structure

Iguchi, Masahide; Saito, Toru; Kawano, Katsumi; Chida, Yutaka; Nakajima, Hideo; Ogawa, Tsuyoshi*; Katayama, Yoshinori*; Ogata, Hiroshige*; Minemura, Toshiyuki*; Tokai, Daisuke*; et al.

Fusion Engineering and Design, 88(9-10), p.2520 - 2524, 2013/10

 Times Cited Count:10 Percentile:61.16(Nuclear Science & Technology)

ITER TFC structures are large welding structures made of heavy thick stainless steels. JAEA plans to apply narrow gap TIG welding with FMYJJ1 which is full austenitic stainless filler material to manufacture TFC structure. FMYJJ1 is specified in "Codes for Fusion Facilities -Rules on Superconducting Magnet Structure (2008)". In order to evaluate effect of base material combinations and thickness of welded joint on tensile properties at 4 K, tensile tests were conducted at 4 K by using tensile specimens taken from 40 mm thickness weld joints of four combinations and 200 mm thickness ones of two combinations of base materials. These weld joints were manufactured by one side narrow gap TIG welding with FMYJJ1. As the results, it was confirmed that yield and tensile strengths of welded joint at 4K were decreased with decreasing of nitrogen of base material, and there were no large distribution of strengths at 4 K along the thickness of welded joints of 200 mm thickness.

Journal Articles

Development of structures for ITER toroidal field coil in Japan

Iguchi, Masahide; Chida, Yutaka; Takano, Katsutoshi; Kawano, Katsumi; Saito, Toru; Nakajima, Hideo; Koizumi, Norikiyo; Minemura, Toshiyuki*; Ogata, Hiroshige*; Ogawa, Tsuyoshi*; et al.

IEEE Transactions on Applied Superconductivity, 22(3), p.4203305_1 - 4203305_5, 2012/06

 Times Cited Count:9 Percentile:47.58(Engineering, Electrical & Electronic)

Japan Atomic Energy Agency (JAEA) has responsibility to procure 19 structures for ITER toroidal field (TF) coils as in-kind components. JAEA plans to use materials specified in the material section of "Codes for Fusion Facilities; Rules on Superconducting Magnet Structure (2008)" issued by the Japan Society of Mechanical Engineers (JSME) in 2008. Large forged products were produced and their mechanical properties at 4K were evaluated. In addition, the following activities have been performed; (1) to optimize the design of each weld type identified in the manufacturing sequence, (2) to qualify typical welding procedure including repair, (3) to establish welding techniques other than narrow gap TIG welding with FMYJJ1, (4) to demonstrate the manufacturing procedures through manufacture of 1-m mockups and full-scale segments of TFC structure. This paper describes the results of material qualification and industrialization activities of manufacturing processes of ITER TFC structure.

Journal Articles

Development in fabrication structures for the ITER toroidal field coils

Iguchi, Masahide; Chida, Yutaka; Nakajima, Hideo; Ogawa, Tsuyoshi*; Katayama, Yoshinori*; Ogata, Hiroshige*; Minemura, Toshiyuki*; Miyabe, Keisuke*; Tokai, Daisuke*; Niimi, Kenichiro*

Teion Kogaku, 47(3), p.193 - 199, 2012/03

Japan Atomic Energy Agency (JAEA) has conducted qualification and rationalization activities in Japan in order to rationalize manufacturing procedure of ITER Toroidal Field (TF) coil structures. The activities included qualification of structural materials and qualification of welding procedure according to Japan Society of Mechanical Engineers (JSME) code constituted for fusion devices, demonstration of the manufacturing method and procedures through full-scale segments of TF coil structure. From results of these activities, JAEA confirmed applicability of JSME code to actual series TF coil structures as quality control method hence the quality of structural materials and weld joints of Gas Tungsten Arc Welding (GTAW) were satisfied ITER requirement. In addition, JAEA obtained knowledge of welding deformation of actual TF coil structures. This paper describes results of these qualification and development activities for TF coil structure.

Journal Articles

In-beam $$gamma$$-ray spectroscopy of $$^{248,250,252}$$Cf by neutron-transfer reactions using a Cf target

Takahashi, Ryuta; Ishii, Tetsuro; Asai, Masato; Nagae, Daisuke*; Makii, Hiroyuki; Tsukada, Kazuaki; Toyoshima, Atsushi; Ishii, Yasuo; Matsuda, Makoto; Makishima, Akiyasu*; et al.

Physical Review C, 81(5), p.057303_1 - 057303_4, 2010/05

 Times Cited Count:13 Percentile:63.2(Physics, Nuclear)

The ground-state bands of $$^{248,250,252}$$Cf have been established up to 10$$^{+}$$, 12$$^{+}$$, and 10$$^{+}$$ states, respectively, by in-beam $$gamma$$-ray spectroscopy using neutron-transfer reactions with a $$^{18}$$O beam and a highly radioactive Cf target. The deexcitation $$gamma$$ rays in $$^{248,250,252}$$Cf were identified by taking coincidences with outgoing particles of $$^{16-19}$$O measured with Si $$Delta E$$-$$E$$ detectors, and by selecting their kinetic energies. This is the first in-beam $$gamma$$-ray spectroscopy for Cf isotopes.

JAEA Reports

Excavation analysis of vertical shaft in sedimentary rock taken into account strain softening and depth variation of rock properties

Sanada, Hiroyuki; Matsui, Hiroya; Ogawa, Toyokazu*; Kinomura, Koji*; Aoki, Tomoyuki*; Yamamoto, Takuya*

JAEA-Research 2009-050, 57 Pages, 2010/01

JAEA-Research-2009-050.pdf:8.14MB

It is important to understand EDZ in assessing performance of repository and designing of plug. It is known that it remains possible that the large-scale EDZ is generated due to strain localization from boring investigations and tunnel excavation analyses and rock properties changes with increase of depth. Excavation analysis of vertical shaft in sedimentary rock taken into account strain softening, depth variation of rock properties and the actual construction procedure had been done in order to understand EDZ of Horonobe URL. The large-scale EDZ due to strain localization was generated around the border between Koetoi formation and Wakkanai formation. From result obtained from excavation analysis, scale of EDZ obtained from excavation analysis is from 60 cm to 120 cm. And it was estimated that seismic velocity changed by 20 percent, elastic modulus changed by 30 percent and hydraulic conductivity changed by 0.1 m/s order.

Journal Articles

Durability of triple-junction solar cell for HIHT environments, venus and mercury exploration missions

Imaizumi, Mitsuru*; Toyota, Hiroyuki*; Shimada, Takanobu*; Ogawa, Hiroyuki*; Tajima, Michio*; Hisamatsu, Tadashi*; Nakamura, Kazuyo*; Takamoto, Tatsuya*; Sato, Shinichiro; Oshima, Takeshi

Proceedings of the 8th International Workshop on Radiation Effects on Semiconductor Devices for Space Applications (RASEDA-8), p.127 - 130, 2008/12

Results of our study of effects of high-light-intensity and high-temperature conditions (HIHT) on the output performance of an InGaP/GaAs/Ge triple-junction solar cell are described herein. The HIHT conditions are adjusted for spacecraft environments expected for a Venus mission (Planet-C) and a Mercury mission (MMO) to be undertaken by the Japan Aerospace Exploration Agency (JAXA). Measurements of current-voltage characteristics under high light intensity for wide range of cell temperatures exhibit a kinked pattern at 0 current at +200$$^{circ}$$C. The thermal cycle test results for bare cells with a wide temperature range show no output performance degradation. Continuous operation tests of 3J cells under HIHT conditions reveal gradual current output degradation, implying that solar panel design should address decreased output specifically.

Journal Articles

Observation of high-$$j$$ quasiparticle states in $$^{249}$$Cm by in-beam $$gamma$$-ray spectroscopy using heavy-ion transfer reactions

Ishii, Tetsuro; Makii, Hiroyuki*; Asai, Masato; Tsukada, Kazuaki; Toyoshima, Atsushi; Matsuda, Makoto; Makishima, Akiyasu*; Shigematsu, Soichiro*; Kaneko, Junichi*; Shizuma, Toshiyuki; et al.

Physical Review C, 78(5), p.054309_1 - 054309_11, 2008/11

 Times Cited Count:14 Percentile:64.91(Physics, Nuclear)

Journal Articles

Excavation analysis of vertical shaft in sedimentary rock at great depth, taking into account variation in rock physical properties with depth

Ogawa, Toyokazu*; Kinomura, Koji*; Aoki, Tomoyuki*; Yamamoto, Takuya*; Sanada, Hiroyuki; Matsui, Hiroya

Dai-12-Kai Iwa No Rikigaku Kokunai Shimpojiumu Koen Rombunshu (CD-ROM), p.933 - 940, 2008/09

Japan Atomic Energy Agency is planning to conduct researches into geological disposal of high-level radioactive wastes in the Horonobe site located in Hokkaido, Japan. As part of the underground research facilities, two 500m-long vertical shafts have been constructed in tertiary sedimentary rocks since 2005. The surrounding rocks are known to exhibit strain-softening characteristics, necessitating appropriate modelling in the stability analysis. In addition the rocks physical properties often vary with depth. This study shows the results of three-dimensional numerical analysis of the ventilation shaft, taking the construction sequence and the variation of rock properties with depth into consideration.

Journal Articles

Durability of triple-junction solar cell for HIHT environments, venus and mercury exploration missions

Imaizumi, Mitsuru*; Toyota, Hiroyuki*; Shimada, Toru*; Ogawa, Hiroyuki*; Tajima, Michio*; Hisamatsu, Tadashi*; Nakamura, Kazuyo*; Takamoto, Tatsuya*; Sato, Shinichiro; Oshima, Takeshi

Proceedings of 8th European Space Power Conference (CD-ROM), 6 Pages, 2008/09

Results of our study of effects of high-light-intensity and high-temperature conditions (HIHT) on the output performance of an InGaP/GaAs/Ge triple-junction solar cell are described herein. The HIHT conditions are adjusted for spacecraft environments expected for a Venus mission (Planet-C) and a Mercury mission (MMO) to be undertaken by the Japan Aerospace Exploration Agency (JAXA). Measurements of currentvoltage characteristics under high light intensity for a wide range of cell temperatures exhibit a kinked pattern at 0 current at +200$$^{circ}$$C. The thermal cycle test results for bare cells with a wide temperature range show no output performance degradation. Continuous operation tests of 3J cells under HIHT conditions reveal gradual current output degradation, implying that solar panel design should address decreased output specifically.

Journal Articles

In-beam $$gamma$$-ray spectroscopy of neutron-rich nuclei in the uranium region through the heavy-ion transfer reaction

Ishii, Tetsuro; Makii, Hiroyuki; Asai, Masato; Koura, Hiroyuki; Shigematsu, Soichiro*; Tsukada, Kazuaki; Toyoshima, Atsushi; Matsuda, Makoto; Makishima, Akiyasu*; Shizuma, Toshiyuki; et al.

Nuclear Physics A, 805(1-4), p.257 - 259, 2008/06

no abstracts in English

Journal Articles

Evaluation on stability of shaft during excavation, considerating strain softening behavior surrounding rock mass

Kinomura, Koji*; Ogawa, Toyokazu*; Aoki, Tomoyuki*; Yamamoto, Takuya*; Matsui, Hiroya; Sanada, Hiroyuki

Dai-37-Kai Gamban Rikigaku Ni Kansuru Shimpojiumu Koen Rombunshu (CD-ROM), p.307 - 312, 2008/01

no abstracts in English

Journal Articles

Numerical simulation of borehole shape, focusing on strain localization

Ogawa, Toyokazu*; Kinomura, Koji*; Aoki, Tomoyuki*; Yamamoto, Takuya*; Matsui, Hiroya; Sanada, Hiroyuki

Dai-37-Kai Gamban Rikigaku Ni Kansuru Shimpojiumu Koen Rombunshu (CD-ROM), p.301 - 306, 2008/01

no abstracts in English

Journal Articles

Z dependence of the $$N = 152$$ deformed shell gap; In-beam $$gamma$$-ray spectroscopy of neutron-rich $$^{245, 246}$$Pu

Makii, Hiroyuki; Ishii, Tetsuro; Asai, Masato; Tsukada, Kazuaki; Toyoshima, Atsushi; Matsuda, Makoto; Makishima, Akiyasu*; Kaneko, Junichi*; Tome, Hayato*; Ichikawa, Shinichi; et al.

Physical Review C, 76(6), p.061301_1 - 061301_5, 2007/12

 Times Cited Count:28 Percentile:83.47(Physics, Nuclear)

We have measured deexcitation $$gamma$$ rays for the first time in the neutron-rich nuclei of $$^{246}$$Pu$$_{152}$$ and $$^{245}$$Pu$$_{151}$$ produced by the ($$^{18}$$O, $$^{16}$$O) and the ($$^{18}$$O, $$^{17}$$O) reactions, respectively. The ground-state band of $$^{246}$$Pu was established up to 12$$^{+}$$ states. The systematics of the moments of inertia of $$_{94}$$Pu isotopes suggests that the $$N = 152$$ deformed subshell closure disappears in these isotopes. The measurements of deexcitation $$gamma$$ rays in $$^{245}$$Pu shows a small energy spacing between neutron orbitals at $$N = 152$$, which explans the disappearance of the subshell closure.

Journal Articles

In-beam $$gamma$$-ray study of the neutron-rich nuclei of $$^{240}$$U, $$^{246}$$Pu, and $$^{250}$$Cm produced by the ($$^{18}$$O, $$^{16}$$O) reaction

Ishii, Tetsuro; Shigematsu, Soichiro*; Makii, Hiroyuki; Asai, Masato; Tsukada, Kazuaki; Toyoshima, Atsushi; Matsuda, Makoto; Makishima, Akiyasu*; Shizuma, Toshiyuki; Kaneko, Junichi*; et al.

Physics of Atomic Nuclei, 70(8), p.1457 - 1461, 2007/08

 Times Cited Count:9 Percentile:56.38(Physics, Nuclear)

We have measured deexcitation $$gamma$$ rays in the neutron-rich nuclei of $$^{240}$$U, $$^{246}$$Pu and $$^{250}$$Cm. These nuclei were produced by the ($$^{18}$$O, $$^{16}$$O) two-neutron transfer reactions with a 200, 162 and 162 MeV $$^{18}$$O beams and a $$^{238}$$U, $$^{244}$$Pu and $$^{248}$$Cm targets, respectively, using the tandem accelerator at Tokai, Japan. The $$gamma$$ rays in residual nuclei were measured by taking coincidence with scattering particles using Si $$Delta E$$-$$E$$ detectors. We have identified $$gamma$$ rays in $$^{240}$$U, $$^{246}$$Pu and $$^{250}$$Cm by selecting the kinetic energies of $$^{16}$$O particles which correspond to the excitation energies in these nuclei below their neutron separation energies. The ground-state bands of $$^{240}$$U, $$^{246}$$Pu and $$^{250}$$Cm were established up to 12$$^{+}$$ states and the $$K^{pi}=0^{-}$$ octupole band of $$^{240}$$U was established up to 9$$^{-}$$ state. Because the deformations of these nuclei are well developed, the moments of inertia reflect the pairing gap, which is expected to be smaller, resulting in a larger moment of inertia, at the deformed shell closure. We have found that the moment of inertia of the ground-state band of $$^{248}$$Cm$$_{152}$$ is considerably larger than that of $$^{250}$$Cm$$_{154}$$. This fact supports the existence of the deformed subshell closure at $$N=152$$ in Cm isotopes. On the other hand, the moment of inertia of $$^{246}$$Pu$$_{152}$$ was found to be smaller than that of $$^{244}$$Pu$$_{150}$$, which suggests that the deformed subshell closure at $$N=152$$ weakens or disappears in Pu isotopes. These results are consistent with the prediction by a cranking model calculation.

Journal Articles

Ground-state bands of neutron-rich $$^{236}$$Th and $$^{242}$$U nuclei and implication of spherical shell closure at $$N=164$$

Ishii, Tetsuro; Makii, Hiroyuki; Asai, Masato; Koura, Hiroyuki; Shigematsu, Soichiro*; Tsukada, Kazuaki; Toyoshima, Atsushi; Matsuda, Makoto; Makishima, Akiyasu*; Kaneko, Junichi*; et al.

Physical Review C, 76(1), p.011303_1 - 011303_5, 2007/07

 Times Cited Count:14 Percentile:67.84(Physics, Nuclear)

The ground-state bands of the neutron-rich $$^{236}$$Th and $$^{242}$$U nuclei were established up to spin 10 and 8, respectively, by in-beam $$gamma$$-ray spectroscopy using the ($$^{18}$$O, $$^{20}$$Ne) two-proton pickup reaction with a $$^{238}$$U and a $$^{244}$$Pu target. Deexcitation $$gamma$$ rays in $$^{236}$$Th and $$^{242}$$U were identified by selecting the kinetic energies of $$^{20}$$Ne using Si $$Delta E$$-$$E$$ detectors. The excitation energies of the first 2$$^{+}$$ states in U and Pu isotopes have local minima at $$N simeq 146$$, suggesting the possibility that nuclei with $$Z simeq 92$$ have a spherical shell closure of $$N=164$$. Calculation using the Koura-Yamada single-particle potential gives an energy gap of 1.8 MeV at $$N=164$$ for $$^{256}$$U.

Journal Articles

Consideration on poroelastic behavior of siliceous rock mass around an opening by stress-seepage coupled analysis

Sanada, Hiroyuki; Matsui, Hiroya; Yamamoto, Takuya*; Aoki, Tomoyuki*; Ogawa, Toyokazu*; Jo, Mayumi*; Fujii, Yoshiaki*

Heisei-19-Nendo Shigen, Sozai Gakkai Hokkaido Shibu Sokai Oyobi Shunki Koenkai Koen Yoshishu, p.9 - 10, 2007/06

Japan Atomic Energy Agency has been conducting the Horonobe Underground Reseach Laboratory Project as a part of geological isolation research and development at Horonobe-town in Hokkaido, Japan. The rocks around URL have high porosity and low permeability. Therefore, the excess pore pressure caused by URL excavation is possible to affect to the stability of surrounding rock. In this point of view, the authors carried out a stress-seepage coupled analysis to understand the process of the pore pressure change due to excavation and the influence to the stability of surrounding rock and support system. As a result, the large excess pore pressure causes a part in surrounding rock on excavation in an anisotropic initial stress condition and it dissipates with time. The pore pressure change causes the complex deformation in the surrounding rock as well. However, the phenomena are not significant influence to the stability of the surrounding rock and support system.

Journal Articles

Stability analysis of underground opening during excavation, taking time-dependent behaviour of surrounding rock mass into consideration

Ogawa, Toyokazu*; Aoki, Tomoyuki*; Jo, Mayumi*; Matsui, Hiroya; Horii, Hideyuki*

Dai-36-Kai Gamban Rikigaku Ni Kansuru Shimpojiumu Koen Rombunshu, p.39 - 44, 2007/01

In case rock exhibits time-dependent deformation, it is important to evaluate this effect on the tunnel stability, since the rock deforms elastically as well as inelatically even at the time of excavation. This paper introduces an engineering approach method to explain the effect of time-dependent deformation of rock at tunnel excavation stages on the stability. The mechanical parameters to describe a Burgers type rheological model are determined, based upon the drained triaxial creep test results performed on mudstone samples. With the parameters determined, plane-strain 2 dimensional numerical analyses are subsequently performed. In the analysis a couple of indices to describe the degree and timing of time-dependent deformation are introduced with reference to the instantaneous elastic deformation, and their effects on the amount of deformation and support pressure subsequent to the support erection are investigated.

Journal Articles

Ground-state band of the neutron-rich transuranium nucleus $$^{250}$$Cm$$_{154}$$

Ishii, Tetsuro; Shigematsu, Soichiro; Makii, Hiroyuki; Asai, Masato; Tsukada, Kazuaki; Toyoshima, Atsushi; Matsuda, Makoto; Makishima, Akiyasu*; Shizuma, Toshiyuki; Kaneko, Junichi*; et al.

Journal of the Physical Society of Japan, 75(4), p.043201_1 - 043201_4, 2006/04

 Times Cited Count:19 Percentile:68.4(Physics, Multidisciplinary)

The ground-state band of the neutron-rich transuranium nucleus $$^{250}$$Cm was established up to spin 12 by in-beam $$gamma$$-ray spectroscopy using the two-neutron-transfer reaction with a $$^{248}$$Cm target and a 162 MeV $$^{18}$$O beam. Deexcitation $$gamma$$ rays in $$^{250}$$Cm were identified by selecting the kinetic energies of $$^{16}$$O particles with Si $$Delta E$$-$$E$$ detectors. The moment of inertia of $$^{250}$$Cm$$_{154}$$ is considerably smaller than that of $$^{248}$$Cm$$_{152}$$, which supports the existence of the deformed subshell closure at $$N=152$$ in Cm isotopes.

JAEA Reports

Measurement of Seismic Wave Velocities on Soft-Sedimentary Rocks from Horonobe Under Confining Pressure

Ogawa, Toyokazu*; Matsui, Hiroya

JNC TN8400 2005-011, 157 Pages, 2005/02

JNC-TN8400-2005-011.pdf:181.57MB

Horonobe Underground Research Center has been conducting researches and developments into geological disposal of high-level radioactive wastes in sedimentary rocks. In the 2003 borehole investigation programmes, 3 boreholes (HDB-6, 7, and 8) were drilled in order to acquire geoscientific information. This technical report presents the results of elastic wave velocity measurements under confining pressure, carried out on the rock cores extracted from BH HDB-6. The main observations which became clear from the laboratory tests are as follows: 1. the basic physical properties of the rock specimens are consistent with the existing measured values. Moreover, when the wet sample is dried, although P wave velocity at first shows a downward tendency, it increases gradually and approaches the dry velocity as the degree of saturation decreases. Therefore, it is felt that the sample is uniformly dried across the cross-sectional area. ; 2. It appears that the elastic wave velocities of the Horonobe sedimentary rocks are dependent upon pressure. However shear rigidity remains unchanged, even if the saturation conditions of pores change (from wet to dry conditions). In the study of anisotropy of velocities, horizontal velocity seems larger than the vertical one. Although there was no remarkable influence on elastic wave velocities when the loading and unloading of confining pressure were repeated, a certain amount of hysteresis could be observed in porosity. Continuous investigation is required. ; 3. Measured wet velocity may practically be used in evaluating in-situ velocity measurement results.

90 (Records 1-20 displayed on this page)