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Sakurai, Eiko*; Yanai, Kazuhiko*; Ishii, Keizo*; Fujiki, Kota*; Hiraishi, Shingo*; Yamazaki, Hiromichi*; Matsuyama, Shigeo*; Okamura, Nobuyuki*; Yokoyama, Akihito; Kada, Wataru; et al.
JAEA-Review 2011-043, JAEA Takasaki Annual Report 2010, P. 84, 2012/01
Harada, Satoshi*; Ehara, Shigeru*; Ishii, Keizo*; Sato, Takahiro; Yamazaki, Hiromichi*; Matsuyama, Shigeo*; Kamiya, Tomihiro
JAEA-Review 2011-043, JAEA Takasaki Annual Report 2010, P. 89, 2012/01
Sato, Takahiro; Ishii, Keizo*; Kamiya, Tomihiro; Sakai, Takuro; Oikawa, Masakazu*; Arakawa, Kazuo; Matsuyama, Shigeo*; Yamazaki, Hiromichi*
Nuclear Instruments and Methods in Physics Research B, 210, p.113 - 116, 2003/09
Times Cited Count:1 Percentile:12.51(Instruments & Instrumentation)A new detection apparatus for both low energy X-rays and back-scattered protons of MeV energy and its measurement system were developed. The detection apparatus consists of a multi-element detector, pre-amplifiers with active reset system and so on. The detector elements are arranged in the shape of a pentagonal pyramid and fully cover the sample. On each one detection side, 9 detector elements are arranged. The entire detection system consists thus of 45 detector elements. The micro-beam irradiates the sample through the center of the pentagonal pyramid and X-rays emitted from the sample are detected in close to geometry. This novel detection setup has about 10 times the sensitivity of a conventional Micro-PIXE camera. The counting rate of back-scattered protons per detection element is small despite lack of a passive absorber. It appears possible that X-rays from the very small quantity of elements could also be detected. The advantage over a conventional Micro-PIXE camera includes simultaneous detection of back-scattered protons from N, C and O.
Harada, Satoshi*; Tamakawa, Yoshiharu*; Ishii, Keizo*; Tanaka, Akira*; Sato, Takahiro; Matsuyama, Shigeo*; Yamazaki, Hiromichi*; Kamiya, Tomihiro; Sakai, Takuro; Arakawa, Kazuo; et al.
Nuclear Instruments and Methods in Physics Research B, 189(1-4), p.437 - 442, 2002/04
Times Cited Count:1 Percentile:12.5(Instruments & Instrumentation)To study the interactions between the induction of radiation-induced apoptosis and trace elements kinetics, human leukemia cells were irradiated in vitro by Co rays, after which the cells were evaluated for the detection of apoptosis and trace element imaging was carried out. The frequency of apoptosis was obtained by microscopic assay using TUNEL staining. The trace element distribution in the cell was determined by micro-PIXE. In the early phase of apoptosis, the maximum level of Fe accumulation was observed in the cell stroma. In the mid to end phase, Fe accumulation was diminished, and instead, Ca accumulation increased and Zn decreased in the nucleus. There appear to be two steps for the development of apoptosis: (1) the signaling from cell stroma to nucleus by Fe or an Fe-containing enzyme; and (2) the degeneration of the nucleus by Ca-dependent enzyme, and release of Zn from digested nucleus. Those strong accumulations may be new markers for apoptosis.
Sakurai, Eiko*; Yanai, Kazuhiko*; Ishii, Keizo*; Oyama, Ryohei*; Sakamaki, Manabu*; Yamanaka, Kentaro*; Yamazaki, Hiromichi*; Matsuyama, Shigeo*; Kamiya, Tomihiro; Sato, Takahiro; et al.
no journal, ,
no abstracts in English
Sakurai, Eiko*; Ishii, Keizo*; Yamanaka, Kentaro*; Okura, Satoru*; Fujiki, Kota*; Yamazaki, Hiromichi*; Matsuyama, Shigeo*; Kamiya, Tomihiro; Sato, Takahiro; Arakawa, Kazuo*; et al.
no journal, ,
Cognitive degradation and behavior disorder occur under the mental disease caused by stimulant drugs. In this study, it was continuously administered to mice. After that, neuropoiesis of dentate gyrus and trace elements in its brain were analyzed by in-air micro-PIXE. As a result, the distribution of trace elements was different from that of normal mice.
Harada, Satoshi*; Ehara, Shigeru*; Ishii, Keizo*; Yamazaki, Hiromichi*; Matsuyama, Shigeo*; Sato, Takahiro; Kamiya, Tomihiro; Sera, Koichiro*; Saito, Yoshihiro*
no journal, ,
no abstracts in English
Sakurai, Eiko*; Yanai, Kazuhiko*; Okamura, Nobuyuki*; Ishii, Keizo*; Fujiki, Kota*; Hiraishi, Shingo*; Yamazaki, Hiromichi*; Matsuyama, Shigeo*; Yokoyama, Akihito; Kada, Wataru; et al.
no journal, ,
no abstracts in English
Harada, Satoshi*; Ehara, Shigeru*; Ishii, Keizo*; Yamazaki, Hiromichi*; Matsuyama, Shigeo*; Sato, Takahiro; Koka, Masashi; Kamiya, Tomihiro
no journal, ,
no abstracts in English
Ito, Tatsuya; Kim, S.-Y.*; Yamazaki, Hiromichi*; Ishii, Keizo*; Nagaishi, Ryuji; Kimura, Takaumi
no journal, ,
no abstracts in English
Sakurai, Eiko*; Yanai, Kazuhiko*; Okamura, Nobuyuki*; Ishii, Keizo*; Hiraishi, Shingo*; Yamauchi, Shosei*; Yamazaki, Hiromichi*; Matsuyama, Shigeo*; Yokoyama, Akihito; Kada, Wataru; et al.
no journal, ,
no abstracts in English
Sakurai, Eiko*; Ishii, Keizo*; Yamauchi, Shosei*; Yamazaki, Hiromichi*; Kada, Wataru; Koka, Masashi; Sato, Takahiro; Kamiya, Tomihiro
no journal, ,
no abstracts in English