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Tsuchida, Hidetsugu*; Kai, Takeshi; Kitajima, Kensei*; Matsuya, Yusuke; Majima, Takuya*; Saito, Manabu*
European Physical Journal D, 74(10), p.212_1 - 212_7, 2020/10
Times Cited Count：3 Percentile：17.64(Optics)Fundamental study of interaction between biomolecules and heavy ions in water is very important to predict an initial stage of radiation biological effects. A heavy ion irradiation experiment into droplet target assumed as a biological system in a vacuum was performed to measure production yields of cations and anions for glycine, which was ejected from the droplet target to the vacuum. However, the production mechanisms have been unknown. The PHITS code adapting ion track structure mode was used to analyze the production mechanisms from the dose evaluation at the surface between the vacuum and the water. It is found that induction yields of ionization and excitation, and dissociative electron attachment involved in the secondary electrons were correlated with the production yields of cations and anions of the glycine. The results provide us newly scientific insights to predict an initial stage of radiation biological effects.
Ueda, Yoshio*; Oya, Kaoru*; Ashikawa, Naoko*; Ito, Atsushi*; Ono, Tadayoshi*; Kato, Daiji*; Kawashima, Hisato; Kawamura, Gakushi*; Kenmotsu, Takahiro*; Saito, Seiki*; et al.
Purazuma, Kaku Yugo Gakkai-Shi, 88(9), p.484 - 502, 2012/09
no abstracts in English
Fujimoto, Hirofumi*; Higuchi, Mariko; Koike, Manabu*; Ode, Hirotaka*; Pinak, M.; Kotulic Bunta, J.*; Nemoto, Toshiyuki*; Sakudo, Takashi*; Honda, Naoko*; Maekawa, Hideaki*; et al.
Journal of Computational Chemistry, 33(3), p.239 - 246, 2012/01
Times Cited Count：37 Percentile：64.85(Chemistry, Multidisciplinary)Lysine acetylation is one of the most common protein post transcriptional modifications. The acetylation effects of lysine residues on Ku protein were examined herein applying several computer simulation techniques. Acetylation of the lysine residues did not reduce the affinity between Ku and its substrate, DNA, in spite of the fact that the substitution of lysine with glutamine (KQ mutant) reduced the affinity of Ku for DNA, or the substitution of lysine with arginine (KR mutant) did not reduce it, as previously reported in experimental studies. These results suggest that the effects of in vivo acetylation may be overestimated when the KQ mutant is employed in mimicry of the acetylated protein.
Hoshino, Kazuo; Toma, Mitsunori*; Kawamura, Gakushi*; Saito, Seiki*; Ito, Atsushi*
Purazuma, Kaku Yugo Gakkai-Shi, 86(12), p.698 - 705, 2010/12
no abstracts in English
; ; Katsuragi, Satoru; *; ; *; *; *; Sanokawa, Konomo; ; et al.
Nihon Genshiryoku Gakkai-Shi, 17(7), p.329 - 348, 1975/07
no abstracts in English
Saito, Shigeru; Wakui, Takashi; Tsukada, Manabu*; Yamashita, Naoki; Sano, Naruto; Dai, Y.*; Futakawa, Masatoshi
no journal, ,
Post irradiation examination (PIE) of the MEGAPIE (MEGAwatt Pilot Experiment) project has been performed on the samples allotted to JAEA. In the experiments, specimens for tensile test are prepared by taking from the component of the MEGAPIE target such as the beam window (BW) of T91. The irradiation temperatures were about 250 
C and the displacement-damage levels ranged between 0.75 and 1.74 dpa. After the tensile tests, SP specimens are prepared from the grip part of the tested tensile specimens. Testing temperatures for SP tests ranged from -150C to 250C. From the area of the load-displacement curves (LDC) of the SP tests, ductile-brittle transition temperature (DBTT) was evaluated. Comparison of these data with previous STIP data showed similar values. In addition, the yield stress and ultimate tensile strength were calculated from the SP tests results by applying the conversion equation. These were compared with the results of the tensile tests and found to be in good agreement.
