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, induced by ionizing radiation in 
Kimura, Takafumi*; Takanami, Takako*; Sakashita, Tetsuya; Wada, Seiichi*; Kobayashi, Yasuhiko; Higashitani, Atsushi*
Radiation Research, 178(4), p.313 - 320, 2012/10
Times Cited Count：8 Percentile：41.9(Biology)Here, we found that exposure to ionizing radiation (IR) induce certain innate immune response gene of in the intestine. Pre-treatment with IR before seeding on 
lawn plate, significantly increased survival rate in the nematode. IR induction of gene was highly dependent on the ELT-2 transcription factor and p38 MAPK. Moreover, the insulin/IGF-1 signal pathway works as an enhancer of induction of this gene. Silencing of the gene led to growth retardation after IR irradiation. Finally, we describe the cross-tolerance between the responses to radiation exposure and innate immune system.
Kimura, Atsushi; Taguchi, Mitsumasa; Kondo, Takafumi*; Yang, J.*; Nagaishi, Ryuji; Yoshida, Yoichi*; Hirota, Koichi
Radiation Physics and Chemistry, 79(11), p.1159 - 1164, 2010/11
Times Cited Count：3 Percentile：24.08(Chemistry, Physical)Much of this past research has focused on finding more effective reactions between charged reactive species in room temperature ionic liquid (RTILs), which have a coulombic field. Reactions in RTILs involving the charged reactive species, particularly solvated electrons, have been studied by the techniques of radiation chemistry. The reaction behavior of halophenols in RTILs were investigated by 
ray and pulsed electron radiolysis. The yield of CP decomposition in the RTILs was almost the same as that of solvated electrons formation. The yield of CP decomposition and phenol formation in the RTILs was low in the presence of electron scavengers such as nitrous oxide, indicating that solvated electrons primarily contributed to the decomposition of CP. The type of halogen group with the exception of fluorine had a negligible effect on the decomposition of halophenols in the RTILs. Therefore, RTILs could be applied as an reaction media for the reduction by ionizing radiation.
; Germ cell response, aging and behaviorSakashita, Tetsuya; Takanami, Takako*; Yanase, Sumino*; Hamada, Nobuyuki*; Suzuki, Michiyo; Kimura, Takafumi*; Kobayashi, Yasuhiko; Ishii, Naoaki*; Higashitani, Atsushi*
Journal of Radiation Research, 51(2), p.107 - 121, 2010/03
Times Cited Count：35 Percentile：63.91(Biology)The study of radiation effect in 
have been carried out over three decades and now allow for understanding at the molecular, cellular and individual levels. This review describes the current knowledge of the biological effects of ionizing irradiation with a scope of the germ line, aging and behavior. 
may be a good 
model system in the field of radiation biology.
Kimura, Atsushi; Taguchi, Mitsumasa; Kondo, Takafumi*; Yang, J.*; Yoshida, Yoichi*; Hirota, Koichi
Radiation Physics and Chemistry, 77(10-12), p.1253 - 1257, 2008/10
Times Cited Count：11 Percentile：59.16(Chemistry, Physical)
Higashitani, Atsushi*; Mori, Chihiro*; Kimura, Takafumi*; Ikenaga, Takahiko*; Takanami, Takako*; Sakashita, Tetsuya; Wada, Seiichi*; Hamada, Nobuyuki*; Kobayashi, Yasuhiko
JAEA-Review 2007-060, JAEA Takasaki Annual Report 2006, P. 112, 2008/03
We investigated the gene expression of following carbon and irradiation using DNA microarray analysis. We observed the 187 and 297 upregulated genes after and carbon irradiation with 100 Gy, respectively, in which 51 genes were upregulated following both irradiations. On the other hand, the 358 and 388 genes were downregulated after and carbon irradiation, respectively.
Taguchi, Mitsumasa; Kimura, Atsushi; Kondo, Takafumi*; Yang, J.*; Yoshida, Yoichi*; Hirota, Koichi
no journal, ,
no abstracts in English
Kimura, Atsushi; Taguchi, Mitsumasa; Hirota, Koichi; Kondo, Takafumi*; Yang, J.*; Yoshida, Yoichi*
no journal, ,
no abstracts in English
Kimura, Atsushi; Taguchi, Mitsumasa; Kondo, Takafumi*; Yang, J.*; Yoshida, Yoichi*; Hirota, Koichi
no journal, ,
no abstracts in English
-ray and pulsed electron radiolysis studies on the reaction of solvated electrons in room temperature ionic liquids of alkylammonium saltsKimura, Atsushi; Taguchi, Mitsumasa; Kondo, Takafumi*; Yang, J.*; Yoshida, Yoichi*; Hirota, Koichi
no journal, ,
no abstracts in English
Kimura, Atsushi; Kondo, Takafumi*; Yang, J.*; Nagaishi, Ryuji; Yoshida, Yoichi*; Taguchi, Mitsumasa
no journal, ,
no abstracts in English
Kimura, Atsushi; Taguchi, Mitsumasa; Kondo, Takafumi*; Yang, J.*; Nagaishi, Ryuji; Yoshida, Yoichi*
no journal, ,
no abstracts in English
Kimura, Atsushi; Kondo, Takafumi*; Yang, J.*; Nagaishi, Ryuji; Yoshida, Yoichi*; Taguchi, Mitsumasa
no journal, ,
no abstracts in English
