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Saito, Wataru*; Hayashi, Kei*; Huang, Z.*; Sugimoto, Kazuya*; Oyama, Kenji*; Happo, Naohisa*; Harada, Masahide; Oikawa, Kenichi; Inamura, Yasuhiro; Hayashi, Koichi*; et al.
ACS Applied Energy Materials (Internet), 4(5), p.5123 - 5131, 2021/05
Times Cited Count:12 Percentile:64.95(Chemistry, Physical)Hayashi, Kei*; Saito, Wataru*; Sugimoto, Kazuya*; Oyama, Kenji*; Hayashi, Koichi*; Happo, Naohisa*; Harada, Masahide; Oikawa, Kenichi; Inamura, Yasuhiro; Miyazaki, Yuzuru*
AIP Advances (Internet), 10(3), p.035115_1 - 035115_7, 2020/03
Times Cited Count:16 Percentile:73.04(Nanoscience & Nanotechnology)Fujiwara, Satoru*; Matsuo, Tatsuhito*; Sugimoto, Yasunobu*; Shibata, Kaoru
Journal of Physical Chemistry Letters (Internet), 10(23), p.7505 - 7509, 2019/12
Times Cited Count:4 Percentile:21.85(Chemistry, Physical)Characterization of the dynamics of disordered polypeptide chains is required to elucidate the behavior of intrinsically disordered proteins and proteins under non-native states related to the folding process. Here we develop a method using quasielastic neutron scattering, combined with small-angle X-ray scattering and dynamic light scattering, to evaluate segmental motions of proteins as well as diffusion of the entire molecules and local side-chain motions. We apply this method to RNase A under the unfolded and molten-globule (MG) states. The diffusion coefficients arising from the segmental motions are evaluated and found to be different between the unfolded and MG states. The values obtained here are consistent with those obtained using the fluorescence-based techniques. These results demonstrate not only feasibility of this method but also usefulness to characterize the behavior of proteins under various disordered states.
Fujiwara, Satoru*; Kono, Fumiaki*; Matsuo, Tatsuhito*; Sugimoto, Yasunobu*; Matsumoto, Tomoharu*; Narita, Tetsuhiro*; Shibata, Kaoru
Journal of Molecular Biology, 431(17), p.3229 - 3245, 2019/08
Times Cited Count:12 Percentile:49.22(Biochemistry & Molecular Biology)-synuclein (Syn) is an intrinsically disordered protein (IDP) with unknown function. Syn is known to form amyloid fibrils, which are implicated with the pathogenesis of Parkinson's disease and other synucleinopathies. Elucidating the mechanism of fibril formation of Syn is therefore important for understanding the mechanism of the pathogenesis of these diseases. Here, using the quasielastic neutron scattering (QENS) and small-angle X-ray scattering (SAXS) techniques, we investigated the dynamic and structural properties of Syn. These results imply that fibril formation of Syn requires not only the enhanced local motions but also the segmental motions such that the proper inter-molecular interactions are possible.
Nakamura, Toshihiro*; Adachi, Sadao*; Fujii, Minoru*; Sugimoto, Hiroshi*; Miura, Kenta*; Yamamoto, Shunya
Physical Review B, 91(16), p.165424_1 - 165424_8, 2015/04
Times Cited Count:16 Percentile:56.51(Materials Science, Multidisciplinary)Semiconductor nanocrystals have unique electrical and optical properties, because of the quantum confinement effect, and the doping of impurities into nanocrystals. In this study, we investigated the photoluminescence (PL) properties of phosphorus- (P) and boron- (B) co-doped Si nanocrystals (Si NCs), which was synthesized using an ion implantation technique. The Si-NC size (average diameter: 3.5, 4.4, 5.2 nm) and the P and B ion doses (0.1-4.510 cm)values were systematically varied. We find that the PL peak energy shifts to lower values with increasing the average diameters of Si NCs and PB ion dose. The results of PL measurements indicate that the PL spectra are due to the band-to-band transition at the reduced Si-NC band gap caused by the formation of impurity and the radiative transitions between defect- and/or impurity-related localized states. It was found that the PL properties can be controlled by varying the Si-NC size as well as the dopant concentration.
Takahashi, Hiroki; Maebara, Sunao; Kojima, Toshiyuki; Narita, Takahiro; Tsutsumi, Kazuyoshi; Sakaki, Hironao; Suzuki, Hiromitsu; Sugimoto, Masayoshi
Fusion Engineering and Design, 89(9-10), p.2066 - 2070, 2014/10
Times Cited Count:0 Percentile:0.01(Nuclear Science & Technology)Takahashi, Ryuichi*; Ishimaru, Yasuhiro*; Shimo, H.*; Bashir, K.*; Senoura, Takeshi*; Sugimoto, Kazuhiko*; Ono, Kazuko*; Suzui, Nobuo; Kawachi, Naoki; Ishii, Satomi; et al.
PLOS ONE (Internet), 9(6), p.e98816_1 - e98816_7, 2014/06
Times Cited Count:51 Percentile:86.7(Multidisciplinary Sciences)Takahashi, Hiroki; Maebara, Sunao; Sakaki, Hironao; Ichikawa, Masahiro; Suzuki, Hiromitsu; Sugimoto, Masayoshi
Progress in Nuclear Science and Technology (Internet), 4, p.261 - 263, 2014/04
An development of accelerator-based neutron irradiation facility is planning to develop materials for a demonstration fusion reactor. To obtain a 14 MeV neutron energy using the neutron-generating D-Li stripping reaction, an injection into liquid lithium flow by a 40 MeV deuteron beam is employed in IFMIF design concept. In the acceleration of deuteron beam, the activation due to the beam loss is critical issue. The activation analyses for the air in an accelerator vault are carried out by PHITS code and DCHAIN code using the experimental data for deuteron induced thick target neutron yield at 5 MeV and 9 MeV for source term.
Takahashi, Hiroki; Maebara, Sunao; Sakaki, Hironao; Suzuki, Hiromitsu; Sugimoto, Masayoshi
JAEA-Conf 2013-002, p.109 - 112, 2013/10
Shinto, Katsuhiro; Vermare, C.*; Asahara, Hiroo; Sugimoto, Masayoshi; Garin, P.*; Maebara, Sunao; Takahashi, Hiroki; Sakaki, Hironao; Kojima, Toshiyuki; Ohira, Shigeru; et al.
Proceedings of 6th Annual Meeting of Particle Accelerator Society of Japan (CD-ROM), p.668 - 670, 2010/03
Progress of the IFMIF/EVEDA prototype accelerator in fiscal year of 2008 is described. All the sub-systems of the prototype accelerator have started to design, settled the plan of the manufacturing and component tests and fixed the design parameters. As a result of the analysis of planning for the engineering validation of the IFMIF accelerator system, the project duration to be prolonged to the end of 2014 including some months for contingency was approved by the BA Steering Committee. In this article, the design status of each accelerator component, the interface between the accelerator components and the IFMIF/EVEDA Accelerator Building settled in International Fusion Energy Research Centre (IFERC) in Rokkasho and the proposed accelerator commissioning plan for the engineering validation will be presented.
Fujiwara, Satoru; Takezawa, Yasunori*; Sugimoto, Yasunobu*; Wakabayashi, Katsuzo*
Journal of Structural Biology, 167(1), p.25 - 35, 2009/07
Times Cited Count:2 Percentile:4.97(Biochemistry & Molecular Biology)In neutron scattering and diffraction, information on variations of scattering length density of molecules of interest can be extracted by the contrast variation technique. In order to explore the possibilities of this contrast variation technique in neutron fiber diffraction, neutron diffraction measurements of skeletal muscles were performed. The neutron fiber diffraction patterns of frog sartorius muscles were measured in the relaxed state and the rigor state, in various DO concentrations. It was shown that there were variations in the scattering length density of the protein regions in the unit cell of the muscle structure. Analysis of the equatorial reflections showed that the phase information of these reflections is obtained, that the scattering length density is different between the thick filament region and the thin filament region, and that the density of the thick filament changes as the state of muscle changes from the relaxed state to the rigor state.
Shinto, Katsuhiro; Vermare, C.*; Harami, Taikan*; Sugimoto, Masayoshi; Garin, P.*; Maebara, Sunao; Sakaki, Hironao; Ohira, Shigeru; Okumura, Yoshikazu; Mosnier, A.*; et al.
Proceedings of 5th Annual Meeting of Particle Accelerator Society of Japan and 33rd Linear Accelerator Meeting in Japan (CD-ROM), p.255 - 258, 2008/00
Yoshikawa, Hiroshi; Sakaki, Hironao; Sako, Hiroyuki; Takahashi, Hiroki; Shen, G.; Kato, Yuko; Ito, Yuichi; Ikeda, Hiroshi*; Ishiyama, Tatsuya*; Tsuchiya, Hitoshi*; et al.
Proceedings of International Conference on Accelerator and Large Experimental Physics Control Systems (ICALEPCS '07) (CD-ROM), p.62 - 64, 2007/10
J-PARC is a large scale facility of the proton accelerators for the multi-purpose of scientific researches in Japan. This facility consists of three accelerators and three experimental stations. Now, J-PARC is under construction, and LINAC is operated for one year, 3GeV synchrotron has just started the commissioning in this October the 1st. The completion of this facility will be next summer. The control system of accelerators established fundamental performance for the initial commissioning. The most important requirement to the control system of this facility is to minimize the activation of accelerator devices. In this paper, we show that the performances of each layer of this control system have been achieved in the initial stage.
Higashitani, Atsushi*; Sugimoto, Tomoko*; Mori, Chihiro*; Suzuki, Yoko*; Saito, Rumiko*; Ichishi, Eiichiro*; Sakashita, Tetsuya; Hamada, Nobuyuki*; Wada, Seiichi*; Kakizaki, Takehiko; et al.
JAEA-Review 2006-042, JAEA Takasaki Annual Report 2005, P. 113, 2007/02
no abstracts in English
Takahashi, Hiroki; Kawase, Masato; Sakaki, Hironao; Yoshikawa, Hiroshi; Ishiyama, Tatsuya*; Ito, Yuichi; Kato, Yuko; Sugimoto, Makoto*; Suzuki, Takahiro*
Proceedings of 3rd Annual Meeting of Particle Accelerator Society of Japan and 31st Linear Accelerator Meeting in Japan (CD-ROM), p.442 - 444, 2006/08
no abstracts in English
Sugimoto, Tomoko*; Dazai, Kumiko*; Sakashita, Tetsuya; Funayama, Tomoo; Wada, Seiichi; Hamada, Nobuyuki*; Kakizaki, Takehiko; Kobayashi, Yasuhiko; Higashitani, Atsushi*
International Journal of Radiation Biology, 82(1), p.31 - 38, 2006/01
Times Cited Count:43 Percentile:93.12(Biology)no abstracts in English
Sako, Hiroyuki; Sakaki, Hironao; Takahashi, Hiroki; Yoshikawa, Hiroshi; Ito, Yuichi; Kato, Yuko; Kawase, Masato; Shen, G.; Kiyomichi, Akio; Kamikubota, Norihiko*; et al.
Proceedings of 3rd Annual Meeting of Particle Accelerator Society of Japan and 31st Linear Accelerator Meeting in Japan (CD-ROM), p.373 - 375, 2006/00
A Relational database (RDB) system, which is the core of the J-PARC Linac control system, has been developed. The beam commissioning of Linac is planned to start in December 2006. The RDB sytem consists of the following databases; "DB1", which records basic device parameters, "DB2", which acquires online EPICS data, "Operation Log DB", which records a history of operating parameters, and "Commissioning DB", which holds information on geometry of devices and commissioning. We report on the development status of each DB as well as status of the unified commissioning environment software which utilizes these databases.
Ishiyama, Tatsuya*; Yoshikawa, Hiroshi; Sakaki, Hironao; Sako, Hiroyuki; Takahashi, Hiroki; Ito, Yuichi; Kato, Yuko; Kawase, Masato; Ueda, Shinji*; Sugimoto, Makoto*; et al.
Proceedings of 3rd Annual Meeting of Particle Accelerator Society of Japan and 31st Linear Accelerator Meeting in Japan (CD-ROM), p.370 - 372, 2006/00
no abstracts in English
Sako, Hiroyuki; Sakaki, Hironao; Takahashi, Hiroki; Yoshikawa, Hiroshi; Ito, Yuichi*; Kato, Yuko*; Kamikubota, Norihiko*; Sugimoto, Makoto*; Watanabe, Kazuhiko*; Ikeda, Hiroshi*; et al.
Proceedings of 2nd Annual Meeting of Particle Accelerator Society of Japan and 30th Linear Accelerator Meeting in Japan, p.462 - 464, 2005/07
Current status of the RDB system in J-PARC LINAC is presented. The machine database records static data of devices and the control system, whereas the operation log database records a history of operation parameters. The overall design of control flow among high-level applications, simulators, and database is described. Then results of a control test of the power supply for DTQ, and a prototype test of the operation log database in MEBT1 test bench at KEK are reported. In the end, a scheme to generate simulation configuration files from RDB is shown.
Watanabe, Kazuhiko*; Yoshikawa, Hiroshi; Sakaki, Hironao; Takahashi, Hiroki; Kawase, Masato*; Sugimoto, Makoto*
Proceedings of 2nd Annual Meeting of Particle Accelerator Society of Japan and 30th Linear Accelerator Meeting in Japan, p.451 - 453, 2005/07
In J-PARC, we manage the accelerator devices data using the relational database. It is used for managing physical value of all devices. We request the database to generate EPICS records, and the managed data must always the latest. Some data is treated by operator who doesn't have enough experience of database input. If they feel the input is difficult, the input of the database stagnates. In the worst case, the database might not be used. This paper reports the database GUI for operator who doesn't have enough experience of database.