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Omichi, Masaaki*; Asano, Atsushi*; Tsukuda, Satoshi*; Takano, Katsuyoshi*; Sugimoto, Masaki; Saeki, Akinori*; Sakamaki, Daisuke*; Onoda, Akira*; Hayashi, Takashi*; Seki, Shu*
Nature Communications (Internet), 5, p.3718_1 - 3718_8, 2014/04
Times Cited Count:35 Percentile:78.11(Multidisciplinary Sciences)Protein nanowires exhibiting specific biological activities hold promise for interacting with living cells and controlling and predicting biological responses such as apoptosis, endocytosis and cell adhesion. Here we report the result of the interaction of a single high-energy charged particle with protein molecules. Degradation of the human serum albumin nanowires was examined using trypsin. The biotinylated human serum albumin nanowires bound avidin, demonstrating the high affinity of the nanowires. Human serum albumin-avidin hybrid nanowires were also fabricated from a solid state mixture and exhibited good mechanical strength. The biotinylated human serum albumin nanowires can be transformed into nanowires exhibiting a biological function such as avidin-biotinyl interactions and peroxidase activity. The present technique is a versatile platform for functionalizing the surface of any protein molecule with an extremely large surface area.
Ito, Chikara; Ito, Keisuke; Ishikawa, Takashi; Yoshida, Akihiro; Sanada, Yukihisa; Torii, Tatsuo; Notomi, Akihiro*; Wakabayashi, Genichiro*; Miyazaki, Nobuyuki*
Hoshasen, 39(1), p.7 - 11, 2013/09
no abstracts in English
Hayashi, Takafumi*; Suyama, Kenya; Mochizuki, Hiroki*; Nomura, Yasushi
JAERI-Tech 2001-041, 158 Pages, 2001/06
no abstracts in English
Torii, Tatsuo; Sanada, Yukihisa; Kurosawa, Shunsuke*; Hayashi, Takashi*; Sakagami, Takahide*; Kodama, Shyohei*
no journal, ,
In the decommissioning of the Fukushima Daiichi Nuclear Power Plant, non-destructive inspection of piping inside and outside the facility and inspection of contamination inside the piping after removal of the piping is an important issue. In order to set targets for nondestructive inspection inside the piping, we interviewed TEPCO and confirmed the following conditions: the diameters of pipes commonly used in the 1F facility (500A and 25A), hydrogen gas containing -ray emitting nuclides, deposits, and moisture inside the pipes. Based on this situation, the two major themes of the research design were nondestructive inspection for internal penetration and radiological imaging. In this series of presentations, we will introduce the research plan and some of the results related to radiation imaging.