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Journal Articles

Microdosimetric evaluation of the neutron field for BNCT at Kyoto University Reactor by using the PHITS code

Baba, Hiromi*; Onizuka, Yoshihiko*; Nakao, Minoru*; Fukahori, Mai*; Sato, Tatsuhiko; Sakurai, Yoshinori*; Tanaka, Hiroki*; Endo, Satoru*

Radiation Protection Dosimetry, 143(2-4), p.528 - 532, 2011/02

 Times Cited Count:7 Percentile:53.54(Environmental Sciences)

The PHITS simulation were performed to reproduce the geometrical setup of an experiment that measured the microdosimetric energy distributions at the Kyoto University Reactor (KUR) where two types of tissue equivalent proportional counters (TEPC) were used, one with A-150 wall alone and another with a 50 ppm boron loaded A-150 wall. It was found that the PHITS code is a useful tool for the simulation of the energy deposited in tissue in BNCT based on the comparisons with experimental results.

Journal Articles

A Combination use of boron and gadolinium compounds in ${it In vitro}$ NCT trial

Zhang, T.*; Matsumura, Akira*; Yamamoto, Tetsuya*; Yoshida, Fumiyo*; Sakurai, Yoshinori*; Kumada, Hiroaki; Yamamoto, Kazuyoshi; Nose, Tadao*

Research and Development in Neutron Capture Therapy, p.819 - 824, 2002/09

From present study, the irradiation effect by using combination of Boron and Gd, showed various irradiation effects (additive effect, less than additive effect, non additive effect), which depend on Gd concentration. The additive effect will be occurred when using a combination of Gd and Boron with low concentration, however, adding Gd to high concentration will reduce additive effect resulting in less than additive to finally non-additive effect. This result indicate that achieving suitable concentrations of Gd and Boron together in tumors may increase the therapy effect, but achieving excess concentration of Gd with Boron together in tumor may cause negative therapeuitic effect.

Journal Articles

Clinical review of boron neutron capture therapy and a proposed strategy using epithermal neutron beams in Japan

Nakagawa, Yoshinobu*; Pooh, K. H.*; Kageji, Teruyoshi*; Uyama, Shinichi*; Kobayashi, Toru*; Sakurai, Yoshinori*; Matsumura, Akira*; Yamamoto, Tetsuya*; Kumada, Hiroaki

Research and Development in Neutron Capture Therapy, p.1113 - 1116, 2002/09

To make a new protocol using epithermal neutron beam for high-grade glioma patients, we elucidated the relationship between the radiation dose, histological tumor grade, and clinical outcome. One hundred and eighty-three patients with kinds of brain tumors were treated by BNCT since 1968, however, we performed a retrospective study of 105 patients with glial tumors treated in Japan between 1978 and 1997. As for the radiation side effect, we analyzed all patients(n=159) treated between 1977 and 2001. Ten patients with glioblastoma were treated according to the new protocol using epithermal neutron.

Journal Articles

Radiobiogical characterization of epithermal and mixed thermal-epithermal beams at JRR-4

Yamamoto, Tetsuya*; Matsumura, Akira*; Shibata, Yasushi*; Nose, Tadao*; Yamamoto, Kazuyoshi; Kumada, Hiroaki; Hori, Naohiko; Torii, Yoshiya; Ono, Koji*; Kobayashi, Toru*; et al.

Proceedings of 9th International Symposium on Neutron Capture Therapy for Cancer, p.205 - 206, 2000/10

no abstracts in English

Journal Articles

Effect of fuel grain size on reactivity

Okuno, Hiroshi; Naito, Yoshitaka; Sakurai, Y.*

Journal of Nuclear Science and Technology, 28(10), p.958 - 960, 1991/10

no abstracts in English

JAEA Reports

Effects of UO$$_{2}$$ fuel grain size on reactivity; Continuous energy Monte Carlo calculations

Sakurai, Y.*; Okuno, Hiroshi; Naito, Yoshitaka

JAERI-M 91-137, 35 Pages, 1991/09

JAERI-M-91-137.pdf:0.88MB

no abstracts in English

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