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Horiguchi, Hironori; Nakamura, Takemi; Motohashi, Jun; Kashimura, Takanori; Ichimura, Shigeju; Sasajima, Fumio
JAEA-Technology 2012-003, 38 Pages, 2012/03
JAEA-Technology-2012-003.pdf:2.55MB
Clinical trials of boron neutron capture therapy (BNCT) for malignant brain tumors and head and neck cancers have been performed at the research reactor JRR-4. BNCT is a kind of radiation therapy using a nuclear reaction with thermal neutrons and boron (
B) elements administered to a patient. The design specifications of all types of reflector elements were changed due to a trouble of a reflector element in JRR-4. In the production of the new reflector elements, they were designed with the influence for the neutron beam facility by the analytical calculation. After the installation of the new reflector elements, the performance of the neutron beam facility was verified by measurement such as a free air experiment and a water phantom experiment. The calculation error used in the treatment planning for BNCT can be estimated by comparing the results of our calculation with the corresponding experimental data.
Endo, Kiyoshi*; Matsumura, Akira*; Yamamoto, Tetsuya*; Nose, Tadao*; Yamamoto, Kazuyoshi; Kumada, Hiroaki; Kishi, Toshiaki; Torii, Yoshiya; Kashimura, Takanori*; Otake, Shinichi*
Research and Development in Neutron Capture Therapy, p.425 - 430, 2002/09
Using the Rapid Prototyping Technique, we produced a realistic phantom as a formative model of a patient head. This realistic phantom will contribute to verification of our planning system. However, cross-correlation among the calculations using the JAERI Computational Dosimetry System (JCDS), the realistic phantom, and the in vivo measurements were not fully completed because of the difficulty involved in modeling a post-surgical brain and a thermal neutron shield. The experimental simulation technique using the realistic phantom is a useful tool for more reliable dose planning for the intraoperative BNCT.
Matsushita, Akira*; Yamamoto, Tetsuya*; Matsumura, Akira*; Nose, Tadao*; Yamamoto, Kazuyoshi; Kumada, Hiroaki; Torii, Yoshiya; Kashimura, Takanori*; Otake, Shinichi*
Research and Development in Neutron Capture Therapy, p.141 - 143, 2002/09
A thermal-epithermal mixed beam "Thermal Neutron Beam Mode I" was used in the eleven sessions of boron neutron capture therapy which have been performed at JRR-4 from 1998. We are planning to use an epithermal beam for the treatment of deeper tumors in the next trial of the intraoperative BNCT. In this study, "Epi-12" which was made by putting up a cadmium shutter of "Thermal Neutron Beam Mode I" was investigated for the clinical benefits and safety by epithermal beams. Decrease of fast neutron contamination ratio in Epi-12 mode is the advantage for BNCT, particular in the intraoperative BNCT. Because fast neutron on the brain surface is one of the critical factors in the intraoperative BNCT in which the plain beam directly interacts the normal structures. Furthermore a mixture of mode Epi-12 and Th-12 will provide various dose distribution designs. It may be used as a new method to control the best distribution for individual tumors.
Oga, Tokumichi; ; ; *; Ito, Takao; *; Kawai, Mikito; *; Komata, Masao; Kunieda, Shunsuke; et al.
JAERI-Tech 95-044, 147 Pages, 1995/09
no abstracts in English
Kuriyama, Masaaki; Ohara, Yoshihiro; ; ; Hanada, Masaya; Inoue, Takashi; *; *; Ito, Takao; Kawai, Mikito; et al.
Fusion Technology 1992, Vol.1, p.564 - 568, 1993/00
no abstracts in English
; ; ; ; ; ; ; ; ; ; et al.
JAERI-M 83-194, 238 Pages, 1983/12
no abstracts in English
; ; ; ; Kazawa, Minoru; ; ; ; ; ; et al.
Shinku, 26(4), p.300 - 311, 1983/00
no abstracts in English
Motohashi, Jun; Yagi, Masahiro; Kishi, Toshiaki; Kashimura, Takanori
no journal, ,
no abstracts in English
