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Journal Articles

Evaluation of RBE-weighted doses for various radiotherapy beams based on a microdosimetric function implemented in PHITS

Takada, Kenta*; Sato, Tatsuhiko; Kumada, Hiroaki*; Sakurai, Hideyuki*; Sakae, Takeji*

Journal of Physics; Conference Series, 1662, p.012004_1 - 012004_6, 2020/10

The University of Tsukuba has developed a treatment planning system (TPS) for boron neutron capture therapy (BNCT) that uses a Monte Carlo algorithm as a dose calculation engine. In the system, RBE-weighted dose can be also estimated using the microdosimetric function implemented in PHITS. In this study, we calculated the RBE-weighted doses for various radiation therapy beams. Comparison between the calculated results for different radiation therapy beams as well as verification of the calculated data will be presented at the meeting.

Journal Articles

Validation of the physical and RBE-weighted dose estimator based on PHITS coupled with a microdosimetric kinetic model for proton therapy

Takada, Kenta*; Sato, Tatsuhiko; Kumada, Hiroaki*; Koketsu, Junichi*; Takei, Hideyuki*; Sakurai, Hideyuki*; Sakae, Takeji*

Journal of Radiation Research, 59(1), p.91 - 99, 2018/01

 Times Cited Count:34 Percentile:88.03(Biology)

Evaluation of the relative biological effectiveness (RBE)-weighted dose is indispensable in the treatment planning of proton and carbon ion therapies. In this study, we validate the RBE-weighted dose calculated by microdosimetric kinetic model (MKM) in tandem with the Monte Carlo particle transport code PHITS for proton therapy using the full simulation geometry for the beam line of the Proton Medical Research Center at the University of Tsukuba. The physical dose and RBE-weighted dose on the central axis for a 155 MeV monoenergetic and spread-out Bragg peak beam of 60 mm width are evaluated by the method. The calculated results generally agree with the corresponding experimental data very well, though overestimations by approximately 3.2% and 15% at the maximum are observed for the physical and RBE-weighted doses, respectively. This research completes the computational microdosimetric approach based on a combination of PHITS and MKM for all types of radiotherapy that require RBE evaluations.

Journal Articles

Multistep lattice-voxel method utilizing lattice function for Monte-Carlo treatment planning with pixel based voxel model

Kumada, Hiroaki*; Saito, Kimiaki; Nakamura, Takemi; Sakae, Takeji*; Sakurai, Hideyuki*; Matsumura, Akira*; Ono, Koji*

Proceedings of 14th International Congress on Neutron Capture Therapy (ICNCT-14) (CD-ROM), p.238 - 241, 2010/10

Journal Articles

Basic characteristics of a newly developed Si/CdTe Compton camera for medical imaging

Kawachi, Naoki; Watanabe, Shigeki; Sato, Takahiro; Arakawa, Kazuo; Takeda, Shinichiro*; Ishikawa, Shinnosuke*; Aono, Hiroyuki*; Watanabe, Shin*; Yamaguchi, Mitsutaka*; Takahashi, Tadayuki*; et al.

2008 IEEE Nuclear Science Symposium Conference Record (CD-ROM), p.1540 - 1543, 2008/10

Oral presentation

Attempt at visualization and quantification of cisplatin in human lung cancer cell using in-air micro-PIXE

Sakurai, Hideyuki*; Okamoto, Masahiko*; Shin, Masako*; Takeuchi, Aiko*; Hasegawa, Masatoshi*; Sato, Takahiro; Oikawa, Masakazu*; Kamiya, Tomihiro; Arakawa, Kazuo; Nakano, Takashi*

no journal, , 

no abstracts in English

Oral presentation

Multi-tracer imaging with newly developed Si/CdTe Compton camera for medical imaging

Kawachi, Naoki; Watanabe, Shigeki; Sato, Takahiro; Matsuhashi, Shimpei; Arakawa, Kazuo; Takeda, Shinichiro*; Ishikawa, Shinnosuke*; Aono, Hirofumi*; Watanabe, Shin*; Takahashi, Tadayuki*; et al.

no journal, , 

no abstracts in English

Oral presentation

Analysis of trace elements in lung by in-air micro-PIXE

Okamoto, Masahiko*; Sakurai, Hideyuki*; Shin, Masako*; Hasegawa, Masatoshi*; Oikawa, Masakazu*; Sato, Takahiro; Kamiya, Tomihiro; Arakawa, Kazuo; Nakano, Takashi*

no journal, , 

no abstracts in English

Oral presentation

Analysis of radiation-induced cell death in vivo by in-air micro-PIXE

Hasegawa, Masatoshi*; Sakurai, Hideyuki*; Shin, Masako*; Okamoto, Masahiko*; Ishiuchi, Shogo*; Asakawa, Isao*; Tamamoto, Tetsuo*; Ono, Tatsuya*; Oikawa, Masakazu*; Kamiya, Tomihiro; et al.

no journal, , 

no abstracts in English

Oral presentation

Performance characterization of a prototype Si/CdTe Compton camera

Kawachi, Naoki; Watanabe, Shigeki; Fujimaki, Shu; Ishioka, Noriko; Sato, Takahiro; Kamiya, Tomihiro; Arakawa, Kazuo; Watanabe, Shin*; Takeda, Shinichiro*; Ishikawa, Shinnosuke*; et al.

no journal, , 

Oral presentation

Development of Si/CdTe Compton camera for medical imaging

Yamaguchi, Mitsutaka*; Arakawa, Kazuo; Aono, Hiroyuki*; Ishikawa, Shinnosuke*; Kamiya, Tomihiro; Kawachi, Naoki; Odaka, Hirokazu*; Sakurai, Hideyuki*; Sato, Takahiro; Shimada, Hirofumi*; et al.

no journal, , 

Oral presentation

In vivo study of Si/CdTe Compton imaging device

Yoshida, Yukari*; Shimada, Hirofumi*; Kawachi, Naoki; Takeda, Shinichiro*; Ishikawa, Shinnosuke*; Aono, Hiroyuki*; Suzuki, Yoshiyuki*; Sakurai, Hideyuki*; Watanabe, Shin*; Yamaguchi, Mitsutaka*; et al.

no journal, , 

Oral presentation

Clinical application of Si/CdTe Compton imaging device

Suzuki, Yoshiyuki*; Yoshida, Yukari*; Shimada, Hirofumi*; Kato, Hiroyuki*; Sakurai, Hideyuki*; Kawachi, Naoki; Takeda, Shinichiro*; Ishikawa, Shinnosuke*; Aono, Hiroyuki*; Watanabe, Shin*; et al.

no journal, , 

no abstracts in English

Oral presentation

Study of spatial resolution of multi-head Si/CdTe Compton camera for medical application

Yamaguchi, Mitsutaka; Kawachi, Naoki; Watanabe, Shigeki; Sato, Takahiro; Arakawa, Kazuo; Kojima, Takuji; Kamiya, Tomihiro; Watanabe, Shin*; Takeda, Shinichiro*; Odaka, Hirokazu*; et al.

no journal, , 

no abstracts in English

Oral presentation

Next-generation RI imaging instrument; Development of semiconductor Compton camera

Kawachi, Naoki; Yamaguchi, Mitsutaka; Sato, Takahiro; Kamiya, Tomihiro; Arakawa, Kazuo*; Watanabe, Shigeki; Ishioka, Noriko; Takeda, Shinichiro*; Ishikawa, Shinnosuke*; Aono, Hiroyuki*; et al.

no journal, , 

no abstracts in English

Oral presentation

Construction of a BNCT facility using an 8MeV high power proton linac in Ibaraki

Kobayashi, Hitoshi*; Kurihara, Toshikazu*; Matsumoto, Hiroshi*; Yoshioka, Masakazu*; Matsumoto, Noriyuki*; Kumada, Hiroaki*; Matsumura, Akira*; Sakurai, Hideyuki*; Hiraga, Fujio*; Kiyanagi, Yoshiaki*; et al.

no journal, , 

no abstracts in English

15 (Records 1-15 displayed on this page)
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