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Journal Articles

Application of laser-accelerated protons to the demonstration of DNA double-strand breaks in human cancer cells

Yogo, Akifumi; Sato, Katsutoshi; Nishikino, Masaharu; Mori, Michiaki; Teshima, Teruki*; Numasaki, Hodaka*; Murakami, Masao*; Demizu, Yusuke*; Akagi, Takashi*; Nagayama, Shinichi*; et al.

Applied Physics Letters, 94(18), p.181502_1 - 181502_3, 2009/05

 Times Cited Count:109 Percentile:94.78(Physics, Applied)

Oral presentation

Current status of the HIBMC, providing particle beam radiation therapy for more than 2,600 patients, and the prospects of laser-driven proton radiotherapy

Murakami, Masao*; Demizu, Yusuke*; Niwa, Yasue*; Nagayama, Shinichi*; Maeda, Takuya*; Baba, Masashi*; Miyawaki, Daisuke*; Terashima, Kazuki*; Arimura, Takeshi*; Mima, Masayuki*; et al.

no journal, , 

Oral presentation

Comparison of irradiation effects of synchrotron particle beam and laser driven particle beam irradiation in human cancer cell

Maeda, Takuya; Yogo, Akifumi; Demizu, Yusuke*; Hori, Toshihiko; Sakaki, Hironao; Tomoe, Yusuke*; Kondo, Kiminori; Murakami, Masao*

no journal, , 

Oral presentation

Development of a real-time 2D dosimetry system by using a ZnS(Ag) scintillation screen for proton therapy

Akagi, Takashi*; Yamashita, Tomohiro*; Uemoto, Kenji*; Sakaki, Hironao; Demizu, Yusuke*; Fuwa, Nobukazu*

no journal, , 

To develop a real-time two dimensional dosimetry with a scintillation screen. A multidimensional dosimetry system is needed for quality assurance of dose distributions in proton therapy, especially proton therapy with a pencil beam scanning system. An organic scintillation material is often used for the dosimetry systems due to the handleability; however organic scintillators have a poor linearity with respect to the linear energy transfer (LET). Meanwhile, inorganic scintillators have comparably good linearity to the LET; however they are difficult to handle. In this study we employ one of inorganic scintillators, silver- activated zinc sulfide, ZnS(Ag), as a scintillator because of the linearity to the LET.

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