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Journal Articles

Microdosimetric analysis confirms similar biological effectiveness of external exposure to $$gamma$$-rays and internal exposure to $$^{137}$$Cs, $$^{134}$$Cs, and $$^{131}$$I

Sato, Tatsuhiko; Manabe, Kentaro; Hamada, Nobuyuki*

PLOS ONE (Internet), 9(6), p.e99831_1 - e99831_10, 2014/06

 Times Cited Count:9 Percentile:36.9(Multidisciplinary Sciences)

The RBEs of the internal exposure to $$^{137}$$Cs, $$^{134}$$Cs and $$^{131}I$$ were evaluated on the basis of the microdosimetric analysis.

Journal Articles

${it Potato virus Y}$-resistance in the progeny of haploid mutants obtained by the culture of ${it Nicotiana Tabacum}$ L. Anthers exposed to ion beams

Hamada, Kentaro*; Inoue, Masayoshi*; Tanaka, Atsushi; Watanabe, Hiroshi

Plant Biotechnology, 18(4), p.251 - 257, 2001/04

no abstracts in English

Oral presentation

Biological effectiveness of internal exposure relative to external exposure estimated from the absorbed dose distribution at cellular levels

Sato, Tatsuhiko; Manabe, Kentaro; Hamada, Nobuyuki*

no journal, , 

Biological effectiveness of internal exposure relative to external Exposures was estimated from microdosimetry analysis. It can be concluded from the analysis that the risk from internal exposures to Cs-137, Cs-134, and I-131 should be nearly equivalent to that of external exposure to $$gamma$$-rays at the same absorbed dose level, as suggested in the current recommendations of the International Commission on Radiological Protection.

Oral presentation

Estimation of biological effectiveness of internal exposure relative to external exposure considering bystander effect

Sato, Tatsuhiko; Hamada, Nobuyuki*; Manabe, Kentaro

no journal, , 

The risk of internal exposure to $$^{137}$$Cs, $$^{134}$$Cs, and $$^{131}$$I is of great public concern after the accident at the Fukushima-Daiichi Nuclear Power Plant. The relative biological effectiveness (RBE, defined herein as effectiveness of internal exposure relative to the external exposure to $$gamma$$-rays) is occasionally believed to be much greater than unity due to insufficient discussions on the difference of their microdosimetric profiles. We therefore performed a Monte Carlo particle transport simulation in ideally aligned cell systems to calculate the probability densities of absorbed doses in subcellular and intranuclear scales for internal exposures to electrons emitted from $$^{137}$$Cs, $$^{134}$$Cs, and $$^{131}$$I, as well as the external exposure to 662 keV photons. The RBE due to the high ionization density and that for the bystander effect were very close to 1, because the microdosimetric probability densities were nearly identical between the internal exposures and the external exposure from the 662 keV photons. On the other hand, the RBE due to the RI inhomogeneity largely depended on the intranuclear RI concentration and cell size, but their maximum possible RBE was only 1.04 even under conservative assumptions. Thus, it can be concluded from the microdosimetric viewpoint that the risk from internal exposures to $$^{137}$$Cs, $$^{134}$$Cs, and $$^{131}$$I should be nearly equivalent to that of external exposure to $$gamma$$-rays at the same absorbed dose level, as suggested in the current recommendations of the International Commission on Radiological Protection.

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