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Journal Articles

Potential inhibitory effects of low-dose thoron inhalation and ascorbic acid administration on alcohol-induced hepatopathy in mice

Kataoka, Takahiro*; Ishida, Tsuyoshi*; Naoe, Shota*; Kanzaki, Norie; Sakoda, Akihiro; Tanaka, Hiroshi; Mitsunobu, Fumihiro*; Yamaoka, Kiyonori*

Journal of Radiation Research (Internet), 63(5), p.719 - 729, 2022/09

 Times Cited Count:2 Percentile:44.25(Biology)

Journal Articles

Development of ARKADIA-Safety for severe accident evaluation of sodium-cooled fast reactors

Aoyagi, Mitsuhiro; Sonehara, Masateru; Ishida, Shinya; Uchibori, Akihiro; Kawada, Kenichi; Okano, Yasushi; Takata, Takashi

Proceedings of Technical Meeting on State-of-the-art Thermal Hydraulics of Fast Reactors (Internet), 3 Pages, 2022/09

Journal Articles

Radon solubility and diffusion in the skin surface layer

Sakoda, Akihiro; Ishida, Tsuyoshi*; Kanzaki, Norie; Tanaka, Hiroshi; Kataoka, Takahiro*; Mitsunobu, Fumihiro*; Yamaoka, Kiyonori*

International Journal of Environmental Research and Public Health, 19(13), p.7761_1 - 7761_12, 2022/07

 Times Cited Count:0 Percentile:0(Environmental Sciences)

In specific situations such as bathing in a radon spa, where the radon activity concentration in thermal water is far higher than that in air, it has been revealed that radon uptake via skin can occur and should be considered for more precise dose evaluation. The primary aim of the present study was to numerically demonstrate the distribution as well as the degree of diffusion of radon in the skin, with a focus on its surface layers (i.e., stratum corneum). We made a biokinetic model that included diffusion theory at the stratum corneum, and measured radon solubility in the stratum corneum to get a crucial parameter. The implementation of the model suggested that the diffusion coefficient in the stratum corneum was as low as general radon-proof sheets. The depth profile of radon in the skin was found to be that after a 20-minute immersion in water, the radon activity concentration at the top surface skin layer was approximately 1000 times higher than that at the viable skin layer. The information on the position of radon as a radiation source would contribute to special dose evaluation where specific target cell layers are assumed for the skin.

Journal Articles

Hybridization of Bogoliubov quasiparticles between adjacent CuO$$_2$$ layers in the triple-layer cuprate Bi$$_2$$Sr$$_2$$Ca$$_2$$Cu$$_3$$O$$_{10+delta}$$ studied by angle-resolved photoemission spectroscopy

Ideta, Shinichiro*; Johnston, S.*; Yoshida, Teppei*; Tanaka, Kiyohisa*; Mori, Michiyasu; Anzai, Hiroaki*; Ino, Akihiro*; Arita, Masashi*; Namatame, Hirofumi*; Taniguchi, Masaki*; et al.

Physical Review Letters, 127(21), p.217004_1 - 217004_6, 2021/11

 Times Cited Count:6 Percentile:60.19(Physics, Multidisciplinary)

Journal Articles

Comparison of antioxidative effects between radon and thoron inhalation in mouse organs

Kobashi, Yusuke*; Kataoka, Takahiro*; Kanzaki, Norie; Ishida, Tsuyoshi*; Sakoda, Akihiro; Tanaka, Hiroshi; Ishimori, Yuu; Mitsunobu, Fumihiro*; Yamaoka, Kiyonori*

Radiation and Environmental Biophysics, 59(3), p.473 - 482, 2020/08

 Times Cited Count:5 Percentile:39.65(Biology)

Radon therapy has been traditionally performed globally for oxidative stress-related diseases. Many researchers have studied the beneficial effects of radon exposure in living organisms. However, the effects of thoron, a radioisotope of radon, have not been fully examined. In this study, we aimed to compare the biological effects of radon and thoron inhalation on mouse organs with a focus on oxidative stress. Male BALB/c mice were randomly divided into 15 groups: sham inhalation, radon inhalation at a dose of 500 Bq/m$$^{3}$$ or 2000 Bq/m$$^{3}$$, and thoron inhalation at a dose of 500 Bq/m$$^{3}$$ or 2000 Bq/m$$^{3}$$ were carried out. Immediately after inhalation, mouse tissues were excised for biochemical assays. The results showed a significant increase in superoxide dismutase and total glutathione, and a significant decrease in lipid peroxide following thoron inhalation under several conditions. Additionally, similar effects were observed for different doses and inhalation times between radon and thoron. Our results suggest that thoron inhalation also exerts antioxidative effects against oxidative stress in organs. However, the inhalation conditions should be carefully analyzed because of the differences in physical characteristics between radon and thoron.

Journal Articles

Identification of advanced spin-driven thermoelectric materials via interpretable machine learning

Iwasaki, Yuma*; Sawada, Ryoto*; Stanev, V.*; Ishida, Masahiko*; Kirihara, Akihiro*; Omori, Yasutomo*; Someya, Hiroko*; Takeuchi, Ichiro*; Saito, Eiji; Yorozu, Shinichi*

npj Computational Materials (Internet), 5, p.103_1 - 103_6, 2019/10

 Times Cited Count:47 Percentile:87.54(Chemistry, Physical)

Journal Articles

Advanced analysis technology for new material and product development

Sasaki, Hirokazu*; Nishikubo, Hideo*; Nishida, Shinsuke*; Yamazaki, Satoshi*; Nakasaki, Ryusuke*; Isomatsu, Takemi*; Minato, Ryuichiro*; Kinugawa, Kohei*; Imamura, Akihiro*; Otomo, Shinya*; et al.

Furukawa Denko Jiho, (138), p.2 - 10, 2019/02

no abstracts in English

Journal Articles

Machine-learning guided discovery of a new thermoelectric material

Iwasaki, Yuma*; Takeuchi, Ichiro*; Stanev, V.*; Gilad Kusne, A.*; Ishida, Masahiko*; Kirihara, Akihiro*; Ihara, Kazuki*; Sawada, Ryoto*; Terashima, Koichi*; Someya, Hiroko*; et al.

Scientific Reports (Internet), 9, p.2751_1 - 2751_7, 2019/02

 Times Cited Count:61 Percentile:93.15(Multidisciplinary Sciences)

Journal Articles

New precise measurements of muonium hyperfine structure at J-PARC MUSE

Strasser, P.*; Abe, Mitsushi*; Aoki, Masaharu*; Choi, S.*; Fukao, Yoshinori*; Higashi, Yoshitaka*; Higuchi, Takashi*; Iinuma, Hiromi*; Ikedo, Yutaka*; Ishida, Katsuhiko*; et al.

EPJ Web of Conferences, 198, p.00003_1 - 00003_8, 2019/01

 Times Cited Count:13 Percentile:98.93(Quantum Science & Technology)

Journal Articles

Knowledge discovery of suppressive effect of disease and increased anti-oxidative function by low-dose radiation using self-organizing map

Kanzaki, Norie; Kataoka, Takahiro*; Kobashi, Yusuke*; Yunoki, Yuto*; Ishida, Tsuyoshi*; Sakoda, Akihiro; Ishimori, Yuu; Yamaoka, Kiyonori*

Radioisotopes, 67(2), p.43 - 57, 2018/02

We previously reported that low-dose radiation induces the anti-oxidative function in many organ systems of mice. This results in the suppression of several kinds of oxidative stress-induced damage. This study was conducted with the objective of revealing the health effects of low-dose radiation obtained from our previous reports and searching for a new treatment based on low-dose radiation, such as radon therapy. We extracted the characteristics of the effects of low dose radiation suppressing diseases and enhancing the anti-oxidative function using fuzzy answer by self-organizing map (SOM) based on mutual knowledge. The relationship between the suppressive effect and increased antioxidative function was shown in our result, and the concentration dependence of the effect against pain was shown on the output map. Although the effect against other organs depending on concentration was unpredictable, our results indicate that low-dose radiation may also be suitable for treatment of liver disease and brain disease.

Journal Articles

New precise measurement of muonium hyperfine structure interval at J-PARC

Ueno, Yasuhiro*; Aoki, Masaharu*; Fukao, Yoshinori*; Higashi, Yoshitaka*; Higuchi, Takashi*; Iinuma, Hiromi*; Ikedo, Yutaka*; Ishida, Katsuhiko*; Ito, Takashi; Iwasaki, Masahiko*; et al.

Hyperfine Interactions, 238(1), p.14_1 - 14_6, 2017/11

 Times Cited Count:3 Percentile:86.37(Physics, Atomic, Molecular & Chemical)

Journal Articles

Gamma radiation resistance of spin Seebeck devices

Yagmur, A.*; Uchida, Kenichi*; Ihara, Kazuki*; Ioka, Ikuo; Kikkawa, Takashi*; Ono, Madoka*; Endo, Junichi*; Kashiwagi, Kimiaki*; Nakashima, Tetsuya*; Kirihara, Akihiro*; et al.

Applied Physics Letters, 109(24), p.243902_1 - 243902_4, 2016/12

 Times Cited Count:3 Percentile:14.8(Physics, Applied)

Thermoelectric devices based on the spin Seebeck effect (SSE) were irradiated with gamma ($$gamma$$) rays with the total dose of around 3$$times$$10$$^{5}$$ Gy in order to investigate the $$gamma$$-radiation resistance of the devices. To demonstrate this, Pt/Ni$$_{0.2}$$Zn$$_{0.3}$$Fe$$_{2.5}$$O$$_{4}$$/Glass and Pt/Bi$$_{0.1}$$Y$$_{2.9}$$Fe$$_{5}$$O$$_{12}$$/Gd$$_{3}$$Ga$$_{5}$$O$$_{12}$$ SSE devices were used. We confirmed that the thermoelectric, magnetic, and structural properties of the SSE devices are not affected by the $$gamma$$-ray irradiation. This result demonstrates that SSE devices are applicable to thermoelectric generation even in high radiation environments.

Journal Articles

New muonium HFS measurements at J-PARC/MUSE

Strasser, P.*; Aoki, Masaharu*; Fukao, Yoshinori*; Higashi, Yoshitaka*; Higuchi, Takashi*; Iinuma, Hiromi*; Ikedo, Yutaka*; Ishida, Katsuhiko*; Ito, Takashi; Iwasaki, Masahiko*; et al.

Hyperfine Interactions, 237(1), p.124_1 - 124_9, 2016/12

 Times Cited Count:7 Percentile:90.97(Physics, Atomic, Molecular & Chemical)

Journal Articles

Thermoelectric generation based on spin Seebeck effects

Uchida, Kenichi*; Adachi, Hiroto; Kikkawa, Takashi*; Kirihara, Akihiro*; Ishida, Masahiko*; Yorozu, Shinichi*; Maekawa, Sadamichi; Saito, Eiji*

Proceedings of the IEEE, 104(10), p.1946 - 1973, 2016/10

 Times Cited Count:214 Percentile:99.2(Engineering, Electrical & Electronic)

Journal Articles

Neutron irradiation effect of high-density MoO$$_{3}$$ pellets for Mo-99 production, 3

Ishida, Takuya; Suzuki, Yoshitaka; Nishikata, Kaori; Yonekawa, Minoru; Kato, Yoshiaki; Shibata, Akira; Kimura, Akihiro; Matsui, Yoshinori; Tsuchiya, Kunihiko; Sano, Tadafumi*; et al.

KURRI Progress Report 2015, P. 64, 2016/08

no abstracts in English

Journal Articles

Radioactivity decontamination in and around school facilities in Fukushima

Saegusa, Jun; Tagawa, Akihiro; Kurikami, Hiroshi; Iijima, Kazuki; Yoshikawa, Hideki; Tokizawa, Takayuki; Nakayama, Shinichi; Ishida, Junichiro

Mechanical Engineering Journal (Internet), 3(3), p.15-00609_1 - 15-00609_7, 2016/06

After the Fukushima nuclear accident, JAEA lead off demonstration tests to find out effective decontamination methods for various school facilities in Fukushima. It included (1) dose reduction measures at schoolyards, (2) purification of swimming pool water and (3) removal of surface contamination of playground equipments. Through these tests, they established practical methods suitable for each situation; (1) At school yards, dose rates were drastically reduced by removing topsoil which was then placed in trenches of 1 m deep; (2) For the purification of pool water, the flocculation-coagulation treatment was found to be effective for collecting radiocesium dissolved in the water; (3) Demonstration tests for playground equipments, such as horizontal bars and a sandbox wood frame, suggested that effectiveness of decontamination considerably varied depending on the material, paint or coating condition. This paper reviews these demonstrations.

Journal Articles

Technical estimation for mass production of highly-concentrated $$^{rm 99m}$$Tc solution from $$^{99}$$Mo to be obtained by ($$n,gamma$$) reaction; A Preliminary study using inactive Re instead of $$^{rm 99m}$$Tc

Tanase, Masakazu*; Fujisaki, Saburo*; Ota, Akio*; Shiina, Takayuki*; Yamabayashi, Hisamichi*; Takeuchi, Nobuhiro*; Tsuchiya, Kunihiko; Kimura, Akihiro; Suzuki, Yoshitaka; Ishida, Takuya; et al.

Radioisotopes, 65(5), p.237 - 245, 2016/05

no abstracts in English

Journal Articles

Flexible heat-flow sensing sheets based on the longitudinal spin Seebeck effect using one-dimensional spin-current conducting films

Kirihara, Akihiro*; Kondo, Koichi*; Ishida, Masahiko*; Ihara, Kazuki*; Iwasaki, Yuma*; Someya, Hiroko*; Matsuba, Asuka*; Uchida, Kenichi*; Saito, Eiji; Yamamoto, Naoharu*; et al.

Scientific Reports (Internet), 6, p.23114_1 - 23114_7, 2016/03

 Times Cited Count:62 Percentile:90.56(Multidisciplinary Sciences)

Heat-flow sensing is expected to be an important technological component of smart thermal management in the future. Conventionally, the thermoelectric (TE) conversion technique, which is based on the Seebeck effect, has been used to measure a heat flow by converting the flow into electric voltage. However, for ubiquitous heat-flow visualization, thin and flexible sensors with extremely low thermal resistance are highly desired. Recently, another type of TE effect, the longitudinal spin Seebeck effect (LSSE), has aroused great interest because the LSSE potentially offers favourable features for TE applications such as simple thin-film device structures. Here we demonstrate an LSSE-based flexible TE sheet that is especially suitable for a heat-flow sensing application. This TE sheet contained a Ni$$_{0.2}$$Zn$$_{0.3}$$Fe$$_{2.5}$$O$$_4$$ film which was formed on a flexible plastic sheet using a spray-coating method known as ferrite plating. The experimental results suggest that the ferrite-plated film, which has a columnar crystal structure aligned perpendicular to the film plane, functions as a unique one-dimensional spin- current conductor suitable for bendable LSSE-based sensors. This newly developed thin TE sheet may be attached to differently shaped heat sources without obstructing an innate heat flux, paving the way to versatile heat-flow measurements and management.

JAEA Reports

Establishment of experimental system for $$^{99}$$Mo/$$^{99m}$$Tc production by neutron activation method

Ishida, Takuya; Shiina, Takayuki*; Ota, Akio*; Kimura, Akihiro; Nishikata, Kaori; Shibata, Akira; Tanase, Masakazu*; Kobayashi, Masaaki*; Sano, Tadafumi*; Fujihara, Yasuyuki*; et al.

JAEA-Technology 2015-030, 42 Pages, 2015/11

JAEA-Technology-2015-030.pdf:4.82MB

The research and development (R&D) on the production of $$^{99}$$Mo/$$^{99m}$$Tc by neutron activation method ((n, $$gamma$$) method) using JMTR has been carried out in the Neutron Irradiation and Testing Reactor Center. The specific radioactivity of $$^{99}$$Mo by (n, $$gamma$$) method is extremely low compared with that by fission method ((n,f) method), and as a result, the radioactive concentration of the obtained $$^{99m}$$Tc solution is also lowered. To solve the problem, we propose the solvent extraction with methyl ethyl ketone (MEK) for recovery of $$^{99m}$$Tc from $$^{99}$$Mo produced by (n, $$gamma$$) method. We have developed the $$^{99}$$Mo/$$^{99m}$$Tc separation/extraction/concentration devices and have carried out the performance tests for recovery of $$^{99m}$$Tc from $$^{99}$$Mo produced by (n, $$gamma$$) method. In this paper, in order to establish an experimental system for $$^{99}$$Mo/$$^{99m}$$Tc production, the R&D results of the system are summarized on the improvement of the devices for high-recovery rate of $$^{99m}$$Tc, on the dissolution of the pellets, which is the high-density molybdenum trioxide (MoO$$_{3}$$) pellets irradiated in Kyoto University Research Reactor (KUR), on the production of $$^{99m}$$Tc, and on the inspection of the recovered $$^{99m}$$Tc solutions.

Journal Articles

Neutron irradiation effect of high-density MoO$$_{3}$$ pellets for Mo-99 production, 2

Nishikata, Kaori; Ishida, Takuya; Yonekawa, Minoru; Kato, Yoshiaki; Kurosawa, Makoto; Kimura, Akihiro; Matsui, Yoshinori; Tsuchiya, Kunihiko; Sano, Tadafumi*; Fujihara, Yasuyuki*; et al.

KURRI Progress Report 2014, P. 109, 2015/07

As one of effective applications of the Japan Materials Testing Reactor (JMTR), JAEA has a plan to produce $$^{99}$$Mo by (n,$$gamma$$) method ((n,$$gamma$$)$$^{99}$$Mo production), a parent nuclide of $$^{99m}$$Tc. In this study, preliminary irradiation test was carried out with the high-density molybdenum trioxide (MoO$$_{3}$$) pellets in the hydraulic conveyer (HYD) of the Kyoto University Research Reactor (KUR) and the $$^{99m}$$Tc solution extracted from $$^{99}$$Mo was evaluated. After the irradiation test of the high-density MoO$$_{3}$$ pellets in the KUR, $$^{99m}$$Tc was extracted from the Mo solution and the recovery rate of $$^{99m}$$Tc achieved the target values. The $$^{99m}$$Tc solution also got the value that satisfied the standard value for $$^{99m}$$Tc radiopharmaceutical products by the solvent extraction method.

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