Annual report on the environmental radiation monitoring around the Tokai Reprocessing Plant FY2021

Nakada, Akira; Kanai, Katsuta; Seya, Natsumi; Nishimura, Shusaku; Futagawa, Kazuo; Nemoto, Masashi; Tobita, Keiji; Yamada, Ryohei*; Uchiyama, Rei; Yamashita, Daichi; et al.

JAEA-Review 2022-078, 164 Pages, 2023/03

JAEA-Review-2022-078.pdf:2.64MB

Environmental radiation monitoring around the Tokai Reprocessing Plant has been performed by the Nuclear Fuel Cycle Engineering Laboratories, based on "Safety Regulations for the Reprocessing Plant of Japan Atomic Energy Agency, Chapter IV - Environmental Monitoring". This annual report presents the results of the environmental monitoring and the dose estimation to the hypothetical inhabitant due to the radioactivity discharged from the plant to the atmosphere and the sea during April 2021 to March 2022. In this report, some data include the influence of the accidental release from the Fukushima Daiichi Nuclear Power Station of Tokyo Electric Power Co., Inc. (the trade name was changed to Tokyo Electric Power Company Holdings, Inc. on April 1, 2016) in March 2011. Appendices present comprehensive information, such as monitoring programs, monitoring methods, monitoring results and their trends, meteorological data and discharged radioactive wastes. In addition, the data which were influenced by the accidental release and exceeded the normal range of fluctuation in the monitoring, were evaluated.

First isolation and analysis of caesium-bearing microparticles from marine samples in the Pacific coastal area near Fukushima Prefecture

Miura, Hikaru*; Ishimaru, Takashi*; Ito, Yukari*; Kuribara, Yuichi; Otosaka, Shigeyoshi*; Sakaguchi, Aya*; Misumi, Kazuhiro*; Tsumune, Daisuke*; Kubo, Atsushi*; Higaki, Shogo*; et al.

Scientific Reports (Internet), 11, p.5664_1 - 5664_11, 2021/03

https://doi.org/10.1038/s41598-021-85085-w

For the first time, we isolated and investigated seven CsMPs (radioactive caesium-bearing microparticles) from marine particulate matter and sediment. From the elemental composition, the Cs/Cs activity ratio, and the Cs activity per unit volume results, we inferred that the five CsMPs collected from particulate matter were emitted from Unit 2 of the FDNPP, whereas the two CsMPs collected from marine sediment were possibly emitted from Unit 3. The presence of CsMPs can cause overestimation of the solid-water distribution coefficient of Cs in marine sediments and particulate matter and a high apparent radiocaesium concentration factor for marine biota. CsMPs emitted from Unit 2, which were collected from the estuary of a river that flowed through a highly contaminated area, may have been deposited on land and then transported by the river. By contrast, CsMPs emitted from Unit 3 were possibly transported eastward by the wind and deposited directly onto the ocean surface.

Bithiophene with winding vine-shaped molecular asymmetry; Preparation, structural characterization, and enantioselective synthesis

Toyomori, Yuka*; Tsuji, Satoru*; Mitsuda, Shinobu*; Okayama, Yoichi*; Ashida, Shiomi*; Mori, Atsunori*; Kobayashi, Toru; Miyazaki, Yuji; Yaita, Tsuyoshi; Arae, Sachie*; et al.

Bulletin of the Chemical Society of Japan, 89(12), p.1480 - 1486, 2016/09

https://doi.org/10.1246/bcsj.20160265

NHEJ repair rather than HR repair is the primary function to target to enhance radiosensitization at high LET values

Takahashi, Akihisa*; Kubo, Makoto*; Igarashi, Chie*; Yoshida, Yukari*; Funayama, Tomoo; Kobayashi, Yasuhiko; Nakano, Takashi*

JAEA-Review 2014-050, JAEA Takasaki Annual Report 2013, P. 82, 2015/03

https://doi.org/10.11484/jaea-review-2014-050

DNA double-strand breaks (DSBs) induced by ionizing radiation pose a major threat to cell survival. The cell can respond to the presence of DSBs, through two major repair pathways: Homologous recombination (HR) and non-homologous end-joining (NHEJ). Higher levels of cell death are induced by high-LET radiation when compared to low-LET radiation, even at the same doses because of less effective or more inefficient DNA repair. In this study, we examine the effects of radiation with different LET values on DNA DSB repair and radiosensitivity. Wild-type cells and HR deficient (but NHEJ proficient) cells exhibited the high RBE values at LET values of 108 keV/ m. The RBE value for each cell type decreased with increasing LET values over 200 keV/m. Although NHEJ proficient cells had an almost constant SER value, NHEJ deficient cells showed a high SER value when compared to NHEJ proficient cells, even with increasing LET values.

Draft genome sequence of calcium-dependent sp. strain TCA20, isolated from a hot spring containing a high concentration of calcium ions

Fujinami, Shun*; Takeda, Kiyoko*; Onodera, Takefumi*; Sato, Katsuya; Sano, Motohiko*; Takahashi, Yuka*; Narumi, Issey*; Ito, Masahiro*

Genome Announcements (Internet), 2(5), p.e00866-14_1 - e00866-14_2, 2014/09

https://doi.org/10.1128/genomeA.00866-14

Increase in cell motility by carbon ion irradiation via the Rho signaling pathway and its inhibition by the ROCK inhibitor Y-27632 in lung adenocarcinoma A549 cells

Murata, Kazutoshi*; Noda, Shinei*; Oike, Takahiro*; Takahashi, Akihisa*; Yoshida, Yukari*; Suzuki, Yoshiyuki*; Ono, Tatsuya*; Funayama, Tomoo; Kobayashi, Yasuhiko; Takahashi, Takeo*; et al.

Journal of Radiation Research, 55(4), p.658 - 664, 2014/07

https://doi.org/10.1093/jrr/rru002

The effect of carbon ion irradiation on cell motility through the Rho signaling pathway in the human lung adenocarcinoma cell line A549 was studied. At 48 h after irradiation, the cell motility of A549 cells became significantly greater, and the formation of protrusions significantly increased in cells irradiated with carbon ion. The observed increase in cell motility due to carbon ion irradiation was similar to that observed due to X-ray irradiation. Western-blot analysis showed that carbon ion irradiation increased P-MLC2-S19 expression compared with in unirradiated controls, while total MLC2 expression was unchanged. Exposure to a non-toxic concentration of Y-27632, a specific inhibitor of ROCK, reduced the expression of P-MLC2-S19 after C-ion irradiation, resulting in a significant reduction in migration. These data suggest that carbon irradiation increases cell motility in A549 cells via the Rho signaling pathway and that ROCK inhibition reduces that effect.

Three-dimensional and multienergy -ray simultaneous imaging by using a Si/CdTe Compton camera

Suzuki, Yoshiyuki*; Yamaguchi, Mitsutaka; Odaka, Hirokazu*; Shimada, Hirofumi*; Yoshida, Yukari*; Torikai, Kota*; Sato, Takahiro; Arakawa, Kazuo*; Kawachi, Naoki; Watanabe, Shigeki; et al.

Radiology, 267(3), p.941 - 947, 2013/06

https://doi.org/10.1148/radiol.13121194

Synergistic effect of heat shock protein 90 inhibitor, 17-allylamino-17-demethoxygeldanamycin and X-rays, but not carbon-ion beams, on lethality in human oral squamous cell carcinoma cells

Musha, Atsushi*; Yoshida, Yukari*; Takahashi, Takeo*; Ando, Koichi*; Funayama, Tomoo; Kobayashi, Yasuhiko; Negishi, Akihide*; Yokoo, Satoshi*; Nakano, Takashi*

Journal of Radiation Research, 53(4), p.545 - 550, 2012/07

https://doi.org/10.1093/jrr/rrs012

Three-dimensional imaging test for a head module of a Si/CdTe Compton camera for medical application

Yamaguchi, Mitsutaka; Kawachi, Naoki; Kamiya, Tomihiro; Sato, Takahiro; Suzui, Nobuo; Fujimaki, Shu; Odaka, Hirokazu*; Ishikawa, Shinnosuke*; Kokubun, Motohide*; Watanabe, Shin*; et al.

JAEA-Review 2011-043, JAEA Takasaki Annual Report 2010, P. 145, 2012/01

https://doi.org/10.11484/jaea-review-2011-043

no abstracts in English

Effectiveness of carbon-ion beams for apoptosis induction in rat primary immature hippocampal neurons

Kaminuma, Takuya*; Suzuki, Yoshiyuki*; Shirai, Katsuyuki*; Mizui, Toshiyuki*; Noda, Shinei*; Yoshida, Yukari*; Funayama, Tomoo; Takahashi, Takeo*; Kobayashi, Yasuhiko; Shirao, Tomoaki*; et al.

Journal of Radiation Research, 51(6), p.627 - 631, 2010/11

https://doi.org/10.1269/jrr.10050