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Journal Articles

The Effects of essence of chicken on the trace metal distribution in stressful mice brain slices by in-air micro-PIXE

Sakurai, Eiko*; Yanai, Kazuhiko*; Ishii, Keizo*; Fujiki, Kota*; Hiraishi, Shingo*; Yamazaki, Hiromichi*; Matsuyama, Shigeo*; Okamura, Nobuyuki*; Yokoyama, Akihito; Kada, Wataru; et al.

JAEA-Review 2011-043, JAEA Takasaki Annual Report 2010, P. 84, 2012/01

Journal Articles

Increased antitumor effect of chemotherapy, using radiosensitive microcapsules containing anti-RLIP076

Harada, Satoshi*; Ehara, Shigeru*; Ishii, Keizo*; Sato, Takahiro; Yamazaki, Hiromichi*; Matsuyama, Shigeo*; Kamiya, Tomihiro

JAEA-Review 2011-043, JAEA Takasaki Annual Report 2010, P. 89, 2012/01

Journal Articles

Influence of heat treatment on long term creep properties of 9Cr-W-Mo-V-Nb steel

Obara, Satoshi; Wakai, Takashi; Asayama, Tai; Yamada, Yoshiyuki*; Nakazawa, Takanori*; Yamazaki, Masayoshi*; Hongo, Hiromichi*

Tetsu To Hagane, 96(4), p.172 - 181, 2010/04

This paper describes the effect of heat treatment on mechanical properties of 9Cr-W-Mo-V-Nb steel as a part of development of high Cr steel for fast breeder reactor (FBR). The effects of normalizing temperature and tempering temperature and time on creep properties were investigated from the viewpoint of microstructures. Creep strength increased with increase in normalizing temperature from 950$$^{circ}$$C to 1200$$^{circ}$$C. The microstructural factors that improve creep strength are increased amount of MX which precipitated during tempering process and increased dislocation density. In addition, coarsening of prior austenite grain size also contribute to increasing creep strength. Although creep rupture time of 780$$^{circ}$$C-1h tempering specimen was greater than that of 700$$^{circ}$$C-1h and 750$$^{circ}$$C-1h tempering specimen in a long-term region exceeding 20000h at 650$$^{circ}$$C, creep ductility and reduction of area of the former remarkably degraded compared to those of the latter.

Journal Articles

Development of a large-solid-angle and multi-device detection system for elemental analysis

Sato, Takahiro; Ishii, Keizo*; Kamiya, Tomihiro; Sakai, Takuro; Oikawa, Masakazu*; Arakawa, Kazuo; Matsuyama, Shigeo*; Yamazaki, Hiromichi*

Nuclear Instruments and Methods in Physics Research B, 210, p.113 - 116, 2003/09

 Times Cited Count:1 Percentile:12.53(Instruments & Instrumentation)

A new detection apparatus for both low energy X-rays and back-scattered protons of MeV energy and its measurement system were developed. The detection apparatus consists of a multi-element detector, pre-amplifiers with active reset system and so on. The detector elements are arranged in the shape of a pentagonal pyramid and fully cover the sample. On each one detection side, 9 detector elements are arranged. The entire detection system consists thus of 45 detector elements. The micro-beam irradiates the sample through the center of the pentagonal pyramid and X-rays emitted from the sample are detected in close to $$pi$$ geometry. This novel detection setup has about 10 times the sensitivity of a conventional Micro-PIXE camera. The counting rate of back-scattered protons per detection element is small despite lack of a passive absorber. It appears possible that X-rays from the very small quantity of elements could also be detected. The advantage over a conventional Micro-PIXE camera includes simultaneous detection of back-scattered protons from N, C and O.

Journal Articles

The Kinetics of Fe and Ca for the development of radiation-induced apoptosis by micro-PIXE imaging

Harada, Satoshi*; Tamakawa, Yoshiharu*; Ishii, Keizo*; Tanaka, Akira*; Sato, Takahiro; Matsuyama, Shigeo*; Yamazaki, Hiromichi*; Kamiya, Tomihiro; Sakai, Takuro; Arakawa, Kazuo; et al.

Nuclear Instruments and Methods in Physics Research B, 189(1-4), p.437 - 442, 2002/04

 Times Cited Count:1 Percentile:12.51(Instruments & Instrumentation)

To study the interactions between the induction of radiation-induced apoptosis and trace elements kinetics, human leukemia cells were irradiated in vitro by $$^{60}$$Co $$gamma$$ rays, after which the cells were evaluated for the detection of apoptosis and trace element imaging was carried out. The frequency of apoptosis was obtained by microscopic assay using TUNEL staining. The trace element distribution in the cell was determined by micro-PIXE. In the early phase of apoptosis, the maximum level of Fe accumulation was observed in the cell stroma. In the mid to end phase, Fe accumulation was diminished, and instead, Ca accumulation increased and Zn decreased in the nucleus. There appear to be two steps for the development of apoptosis: (1) the signaling from cell stroma to nucleus by Fe or an Fe-containing enzyme; and (2) the degeneration of the nucleus by Ca-dependent enzyme, and release of Zn from digested nucleus. Those strong accumulations may be new markers for apoptosis.

Oral presentation

Effect of heat treatment on high temperature strength of 9Cr-W-Mo-V-Nb steel

Obara, Satoshi; Yamada, Yoshiyuki*; Nakazawa, Takanori*; Yamazaki, Masayoshi*; Hongo, Hiromichi*

no journal, , 

no abstracts in English

Oral presentation

Effect of heat treatment on the creep properties of 9Cr-W-Mo steel

Miyashita, Yuta*; Nakazawa, Takanori*; Obara, Satoshi; Yamazaki, Masayoshi*; Hongo, Hiromichi*

no journal, , 

no abstracts in English

Oral presentation

Application of in-air micro-PIXE to biological sample

Sakurai, Eiko*; Yanai, Kazuhiko*; Ishii, Keizo*; Oyama, Ryohei*; Sakamaki, Manabu*; Yamanaka, Kentaro*; Yamazaki, Hiromichi*; Matsuyama, Shigeo*; Kamiya, Tomihiro; Sato, Takahiro; et al.

no journal, , 

no abstracts in English

Oral presentation

Effect of heat treatment on long term creep properties of ASME grade 92 steel

Obara, Satoshi; Wakai, Takashi; Asayama, Tai; Yamada, Yoshiyuki*; Nakazawa, Takanori*; Yamazaki, Masayoshi*; Hongo, Hiromichi*

no journal, , 

no abstracts in English

Oral presentation

Effects of heat treatments on long term creep properties of 9Cr-W-Mo-V-Nb steel

Obara, Satoshi; Wakai, Takashi; Asayama, Tai; Yamada, Yoshiyuki*; Nakazawa, Takanori*; Yamazaki, Masayoshi*; Hongo, Hiromichi*

no journal, , 

This paper describes the effect of heat treatment on long-term creep properties of 9Cr-W-Mo-V-Nb steel which in the specification of ASME Grade 92 as a part of development of high Cr steel for fast breeder reactor (FBR). The effects of normalizing temperature and tempering temperature and time on long-term creep properties were investigated from the viewpoint of microstructures.

Oral presentation

Change of elemental distribution in sections of brain found by in-air micro-PIXE

Sakurai, Eiko*; Ishii, Keizo*; Yamanaka, Kentaro*; Okura, Satoru*; Fujiki, Kota*; Yamazaki, Hiromichi*; Matsuyama, Shigeo*; Kamiya, Tomihiro; Sato, Takahiro; Arakawa, Kazuo*; et al.

no journal, , 

Cognitive degradation and behavior disorder occur under the mental disease caused by stimulant drugs. In this study, it was continuously administered to mice. After that, neuropoiesis of dentate gyrus and trace elements in its brain were analyzed by in-air micro-PIXE. As a result, the distribution of trace elements was different from that of normal mice.

Oral presentation

Protraction of drug effectiveness using radiosensitive microcapsules in targeted therapy

Harada, Satoshi*; Ehara, Shigeru*; Ishii, Keizo*; Yamazaki, Hiromichi*; Matsuyama, Shigeo*; Sato, Takahiro; Kamiya, Tomihiro; Sera, Koichiro*; Saito, Yoshihiro*

no journal, , 

no abstracts in English

Oral presentation

Evaluation of the anti-stress effect of foods by in-air micro-PIXE

Sakurai, Eiko*; Yanai, Kazuhiko*; Okamura, Nobuyuki*; Ishii, Keizo*; Fujiki, Kota*; Hiraishi, Shingo*; Yamazaki, Hiromichi*; Matsuyama, Shigeo*; Yokoyama, Akihito; Kada, Wataru; et al.

no journal, , 

no abstracts in English

Oral presentation

Miniaturization of microcapsule and its dynamics in a mouse

Harada, Satoshi*; Ehara, Shigeru*; Ishii, Keizo*; Yamazaki, Hiromichi*; Matsuyama, Shigeo*; Sato, Takahiro; Koka, Masashi; Kamiya, Tomihiro

no journal, , 

no abstracts in English

Oral presentation

Study on silica-supported adsorbent for the selective separation of platinum group metals from high level liquid waste

Ito, Tatsuya; Kim, S.-Y.*; Yamazaki, Hiromichi*; Ishii, Keizo*; Nagaishi, Ryuji; Kimura, Takaumi

no journal, , 

no abstracts in English

Oral presentation

Measurement of trace elements in brain tissue of histamine receptor-deficient mice using in-air micro-PIXE

Sakurai, Eiko*; Yanai, Kazuhiko*; Okamura, Nobuyuki*; Ishii, Keizo*; Hiraishi, Shingo*; Yamauchi, Shosei*; Yamazaki, Hiromichi*; Matsuyama, Shigeo*; Yokoyama, Akihito; Kada, Wataru; et al.

no journal, , 

no abstracts in English

Oral presentation

Measurement of trace elements contained in natural water in Iwaki using in-air micro-PIXE method

Sakurai, Eiko*; Ishii, Keizo*; Yamauchi, Shosei*; Yamazaki, Hiromichi*; Kada, Wataru; Koka, Masashi; Sato, Takahiro; Kamiya, Tomihiro

no journal, , 

no abstracts in English

17 (Records 1-17 displayed on this page)
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