Recognition of DNA damage and induction of repair proteins in

Sato, Katsuya; Kikuchi, Masahiro; Narumi, Issei

a DNA damage response mechanism. However, the damage response is poorly understood in . By investigating the function of deinococcal proteins, we found that, unlike in , LexA is not involved in the regulation of RecA in . This, in turn, led us to speculate that has an alternative DNA damage response mechanism with which to control expression. Recently, we discovered that a novel protein regulates the expression of gene. The novel regulatory protein (designated as PprI) also control the induction of gene following irradiation. Thus, possesses unique mechanisms of DNA damage recognition and repair gene induction.