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Report No.

In-air radiobiological dosimetry of JRR-4 neutron beams for boron neutron capture therapy

Yamamoto, Tetsuya*; Matsumura, Akira*; Yamamoto, Kazuyoshi ; Kumada, Hiroaki; Hori, Naohiko ; Torii, Yoshiya ; Endo, Kiyoshi*; Matsushita, Akira*; Yoshida, Fumiyo*; Shibata, Yasushi*; Nose, Tadao*

The RBE of dose components generated in boron neutron capture therapy (BNCT) were separately determined in neutron beams at JRR-4. The cell killing effect of the neutron beam with or without the presence of 10B was highly dependent on the neutron beam used, according to the epithermal and fast neutron content in the beam. RBE (BARBEboron) values of the boron capture reaction for an epithermal (ENB), a mixed thermal-epithermal (TNB-1), and a thermal (TNB-2) neutron beams were 3.99$$pm$$0.24, 3.04$$pm$$0.19 and 1.43$$pm$$0.08, respectively.



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