Failure patterns of high-grade glioma treated with BNCT

Matsuda, Masahide*; Yamamoto, Tetsuya*; Nakai, Kei*; Endo, Kiyoshi*; Kumada, Hiroaki; Kageji, Teruyoshi*; Matsumura, Akira*

To describe the failure patterns and survival seen with high-grade glioma treated with BNCT, the dose distribution and the clinical responses were retrospectively analyzed. BSH-based BNCT was performed in 12 patients with high-grade glioma (grade IV 7, grade III 5). The post-diagnosis median survival time of 12 patients was 19.8 months (range 3.3-47.2). Four cases of local control, 3 of local recurrence, 3 of distant intraparenchymal recurrence and 2 of subarachnoid dissemination were recorded. According to the analysis of the failure patterns, minimum GTV dose of 26 GyEq or more is necessary for local control.

Language	:	English
Journal	:	Proceedings of 12th International Congress on Neutron Capture Therapy (ICNCT-12)
Volume	:
Number	:
Pages	:	p.40 - 42
Publication Year/Month	:	2006/10
Meeting title	:	12th International Congress on Neutron Capture Therapy (ICNCT-12)
Held date	:	2006/10
Location (city)	:	Takamatsu
Location (country)	:	Japan
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DOI for research data	:
Keywords	:	no keyword
Research Facility	:	JRR-4(研究炉4)
Press Release	:
Article of JAEA R&D Review	:
Cooperating Institute	:	筑波大学

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Registration No. : BB20070242
JAEA Abstracts No. : 35001100
Paper Submission No. : 2673

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