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Learning behavior of ${it C. elegans}$ and radiation effects

Sakashita, Tetsuya; Suzuki, Michiyo; Hamada, Nobuyuki*; Ikeda, Daisuke*; Yanase, Sumino*; Ishii, Naoaki*; Kobayashi, Yasuhiko

We studied the effects of $$gamma$$-irradiation on the salt chemotaxis learning of ${it C. elegans}$, that is well known as a model organism for the nervous system. As a result, we found that chemotaxis to NaCl immediately after irradiation was significantly decreased only during the salt chemotaxis learning. In addition, the radiation-induced resoponse is significantly suppressed in the ${it gpc-1}$ mutant. These results suggested that the effects of ionizing radiation on the salt chemotaxis learning behavior of ${it C. elegans}$ mediated through GPC-1 localized in the specific sensory neurons.

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