Influence of methamphetamine on the trace element distribution within a brain

Sakurai, Eiko*; Ishii, Keizo*; Okamura, Nobuyuki*; Sato, Takahiro; Kamiya, Tomihiro; Yanai, Kazuhiko*

The brain section of the mouse which prescribed methamphetamine was analyzed using micro-PIXE. When bromine in the hippocampal dentate gyrus of a mouse which caused the behavioral change, and other amounts of elements were measured, the amount of bromine accumulation was on the decrease, but the accumulation of zinc, iron, and calcium were on the increase. It was suggested that the medicine which gives change to the amount of actions has also affected distribution of the trace element within a brain.