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Problems in clinical practice of domestic supply of $$^{99}$$Mo/$$^{rm 99m}$$Tc; Development of $$^{99}$$Mo/$$^{rm 99m}$$Tc production using accelerator neutrons

Nagai, Yasuki

A new method was proposed to produce $$^{99}$$Mo by the $$^{100}$$Mo(n,2n)$$^{99}$$Mo reaction using intense neutrons from an accelerator by us. About 20% of the demand of $$^{99}$$Mo in Japan could be obtained constantly by the proposed method. In fact, we have shown that the produced $$^{99}$$Mo contained very little RI impurity and the radionuclide purity of $$^{rm 99m}$$Tc separated from $$^{99}$$Mo by sublimation and the labeling efficiency of $$^{rm 99m}$$Tc-MDP exceed the United States Pharmacopeia requirements for a fission product, $$^{99}$$Mo. We expect that the present $$^{99}$$Mo production method will be accepted worldwide to ensure the constant domestic supply of $$^{99}$$Mo.

Language

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Japanese

Journal

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Radioisotopes

Volume

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61

Number

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12

Pages

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p.619 - 624

Publication Year/Month

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2012/12

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Paper URL

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https://doi.org/10.3769/radioisotopes.61.619

DOI for research data

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Keywords

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no keyword

Research Facility

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Press Release

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Article of JAEA R&D Review

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Cooperating Institute

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千代田テクノル

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