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Report No.

A Method of estimate disability-adjusted life years (DALY) as a measure of cancer risk following radiation exposure in Japanese population

Shimada, Kazumasa ; Kai, Michiaki*

In this study, we proposed that disability-adjusted life year (DALY) to estimate radiation cancer risk in Japanese residents. DALY is calculated as the sum of Years of Life Lost (YLL) and Years Lived with Disability (YLD). We separately calculated the excess absolute risk for cancer incidence based on the Excess Relative Risk (ERR) and Excess Absolute Risk (EAR) models. Cancer-specific incidence, mortality rates, and the survival fractions exceeding 5 years have been based on data from the National Cancer Center in Japan. The cancer-specific incidence and mortality rate statistics were from 2010 in Japan; the survival fractions exceeding 5 years were from 2003 to 2005 in Japan. We used disability weights (DW) of cancer according to stage diagnosis/therapy in the WHO table. Table illustrates the results of DALY for each cancer site for Japanese after exposure at 1 Gy dose per 1000 persons. Furthermore, the ratio of DALY for each cancer site per DALY for all solid cancers and the ratio of YLL per DALY for each cancer are shown in this Table. We calculated the DALY of radiation solid cancer risk as a measure of health risk. DALY can be a practical tool that can compare many types of diseases encountered in common public health.



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