Introduction to dismantling and decommissioning chemistry

Sato, Nobuaki*; Kameo, Yutaka; Sato, Soichi; Kumagai, Yuta; Sato, Tomonori; Yamamoto, Masahiro*; Watanabe, Yutaka*; Nagai, Takayuki; Niibori, Yuichi*; Watanabe, Masayuki; et al.

Introduction to Dismantling and Decommissioning Chemistry, 251 Pages, 2024/09

This book focuses on the dismantling and decommissioning of nuclear facilities and reactors that have suffered severe accidents. In Part 1, we introduce basic aspects ranging from fuel chemistry, analytical chemistry, radiation chemistry, corrosion, and decontamination chemistry to waste treatment and disposal. Then, Part 2 covers the chemistry involved in the decommissioning of various nuclear facilities, and discusses what chemical approaches are necessary and possible for the decommissioning of TEPCO's Fukushima Daiichi Nuclear Power Plants, how decommissioning should be carried out, and what kind of research and development and also human resource development are required for this.

Generality assessment of a model considering heterogeneous cancer cells for predicting tumor control probability for stereotactic body radiation therapy against non-small cell lung cancer

Saga, Ryo*; Matsuya, Yusuke; Obara, Hideki*; Komai, Fumio*; Yoshino, Hironori*; Aoki, Masahiko*; Hosokawa, Yoichiro*

Advances in Radiation Oncology (Internet), 9(4), p.101437_1 - 101437_5, 2024/04

https://doi.org/10.1016/j.adro.2023.101437

The curative effects after radiotherapy are evaluated by the index of tumor control probability (TCP), and the treatment regimen has been determined empirically based on clinical experiences. In recent years, in order to determine TCP for any treatment regimens based on cell experiments, it is necessary to consider the existence of radioresistant cancer stem cells, which are included in tumors at from a few to several tens of percent. Our previous study has proposed an integrated microdosimetric-kinetic (IMK) model that explicitly considers cancer stem cells, and successfully reproduced cancer cell death obtained from cell experiments and clinical TCP. However, the verification so far has been limited to comparison with the clinical data of Hirosaki University Hospital, and comparative verification with clinical data of other facilities has not been performed. In this study, we focused on the stereotactic radiotherapy against non-small cell lung cancer that prescribes a large dose at once, and compared the public data collected by meta-analysis with the IMK model. As a result, it was found that the IMK model considering cancer stem cells well reproduced the clinical TCP regardless of the observed facility type. This work would contribute to the development of technology for predicting curative effects of radiotherapy with high precision.

Translational study for stereotactic body radiotherapy against non-small cell lung cancer, including oligometastases, considering cancer stem-like cells enable predicting clinical outcome from data

Saga, Ryo*; Matsuya, Yusuke; Sato, Hikari*; Hasegawa, Kazuki*; Obara, Hideki*; Komai, Fumio*; Yoshino, Hironori*; Aoki, Masahiko*; Hosokawa, Yoichiro*

Radiotherapy and Oncology, p.109444_1 - 109444_9, 2023/00

https://doi.org/10.1016/j.radonc.2022.109444

When treating non-small cell lung cancer (NSCLC), stereotactic body radiotherapy (SBRT) with high-dose irradiation is often utilized. The fractionation schemes and curative effects can be evaluated by mathematical models for predicting cell survival curve. Such model parameters can be determined from in vitro experiment, but they are empirically determined based on experiences in clinics. As such, there is a large gap between in vitro and clinical study. As such background, translational study between in vitro cell survival and clinical curative effects is necessary. In this study, explicitly considering existence of cancer stem-like cells (CSCs), we developed an all-in-one model for predicting both in vitro cell survival and clinical curative effects (integrated microdosimetric-kinetic (IMK) model) and performed retrospective evaluation of clinical outcomes following SBRT for NSCLC in Hirosaki University Hospital. As a result, the IMK model successfully reproduced both in vitro cell survival and the tumor control probability with various fractionation schemes (i.e., 6-10 Gy per fraction). The developed model would contribute on precisely understanding the impact of CSCs on curative effects after SBRT for NSCLC with high precision.

New precise measurements of muonium hyperfine structure at J-PARC MUSE

Strasser, P.*; Abe, Mitsushi*; Aoki, Masaharu*; Choi, S.*; Fukao, Yoshinori*; Higashi, Yoshitaka*; Higuchi, Takashi*; Iinuma, Hiromi*; Ikedo, Yutaka*; Ishida, Katsuhiko*; et al.

EPJ Web of Conferences, 198, p.00003_1 - 00003_8, 2019/01

https://doi.org/10.1051/epjconf/201919800003

New muonium HFS measurements at J-PARC/MUSE

Strasser, P.*; Aoki, Masaharu*; Fukao, Yoshinori*; Higashi, Yoshitaka*; Higuchi, Takashi*; Iinuma, Hiromi*; Ikedo, Yutaka*; Ishida, Katsuhiko*; Ito, Takashi; Iwasaki, Masahiko*; et al.

Hyperfine Interactions, 237(1), p.124_1 - 124_9, 2016/12

https://doi.org/10.1007/s10751-016-1331-4

Nagaoka ferromagnetism in an optical lattice system

Okumura, Masahiko; Yamada, Susumu; Machida, Masahiko; Aoki, Hideo*

Soryushiron Kenkyu, 119(4C), p.F99 - F101, 2012/02

http://ci.nii.ac.jp/naid/110009419056

no abstracts in English

LASSO reconstruction scheme to predict radioactive source distributions inside reactor building rooms; Evaluation activities

Aoki, Yuto; Ito, Rintaro; Kitamura, Akihiro; Machida, Masahiko; Suzuki, Masahiro; Omori, Takazumi; Taniguchi, Tatsuro; Ide, Hiroshi

no journal, , 

Effect of the thermomechanical treatment conditions onto characteristics of chromium-zirconium copper after the solution treatment

Hada, Kazuhiko; Nishi, Hiroshi; Hirose, Takanori; Mori, Kensuke; Aoki, Shoji*; Wada, Masahiko*; Yamamichi, Tetsuo*

no journal, , 

Chromium-zirconium copper as precipitation hardened copper alloy is examined as one of the structural materials used for the ITER in vacuum vessel components. The process that consists of a thermomechanical treatments series of the solution treatment with rapid cooling to obtain the supersaturated solid solution and the aging treatment etc., is adopted in order to obtain the demanded high strength in manufacturing of this alloy material. However, as this alloy is precipitation hardened copper alloy, it is concerned that the great change in the strength characteristic is caused by the thermomechanical treatments conditions, especially the difference of the quenching cooling rate after the solution treatment in manufacturing. In this research, the influence of the quenching cooling rate condition after the solution treatment and the other conditions on this copper alloy was investigated by measuring the tensile test properties of the specimens that are prepared by treatments with some quenching cooling rate conditions after the solution treatment and aging treatment. One of the typical results from this study is that, for the quenching cooling rate after the solution treatment, it was understood that the cooling rate change from 1 to 10C/s causes the great growth in the tensile strength. Therefore, when this alloy component is manufactured by heat history process like HIP process and needed to be treated solution treatment to be use for the structural component, it is important to guarantee the strength of the product by checking the quenching cooling rate after the solution treatment.

Impurity effect in multi-orbital, sign-reversing s-wave superconductors

Nagai, Yuki; Kuroki, Kazuhiko*; Machida, Masahiko; Aoki, Hideo*

no journal, , 

no abstracts in English

JAEAs technical experiences and lessons learned for environmental remediation of Fukushima

Aoki, Isao; Asazuma, Shinichiro; Sudo, Tomoyuki; Komiya, Tomokazu; Nakamura, Masahiko; Uchida, Shinichi; Kozawa, Masachiyo; Sonoda, Takashi; Mikake, Shinichiro; Ikeda, Koki; et al.

no journal, , 

JAEAs technical experiences and lessons learned for environmental remediationof Fukushima. (Technical supports for local governments)