Initialising ...
Initialising ...
Initialising ...
Initialising ...
Initialising ...
Initialising ...
Initialising ...
Furuike, Yoshihiko*; Ouyang, D.*; Tominaga, Taiki*; Matsuo, Tatsuhito*; Mukaiyama, Atsushi*; Kawakita, Yukinobu; Fujiwara, Satoru*; Akiyama, Shuji*
Communications Physics (Internet), 5(1), p.75_1 - 75_12, 2022/04
Times Cited Count:2 Percentile:81.21(Physics, Multidisciplinary)Takeda, Tetsuaki*; Inagaki, Yoshiyuki; Aihara, Jun; Aoki, Takeshi; Fujiwara, Yusuke; Fukaya, Yuji; Goto, Minoru; Ho, H. Q.; Iigaki, Kazuhiko; Imai, Yoshiyuki; et al.
High Temperature Gas-Cooled Reactors; JSME Series in Thermal and Nuclear Power Generation, Vol.5, 464 Pages, 2021/02
As a general overview of the research and development of a High Temperature Gas-cooled Reactor (HTGR) in JAEA, this book describes the achievements by the High Temperature Engineering Test Reactor (HTTR) on the designs, key component technologies such as fuel, reactor internals, high temperature components, etc., and operational experience such as rise-to-power tests, high temperature operation at 950C, safety demonstration tests, etc. In addition, based on the knowledge of the HTTR, the development of designs and component technologies such as high performance fuel, helium gas turbine and hydrogen production by IS process for commercial HTGRs are described. These results are very useful for the future development of HTGRs. This book is published as one of a series of technical books on fossil fuel and nuclear energy systems by the Power Energy Systems Division of the Japan Society of Mechanical Engineers.
Fujiwara, Satoru*; Matsuo, Tatsuhito*; Sugimoto, Yasunobu*; Shibata, Kaoru
Journal of Physical Chemistry Letters (Internet), 10(23), p.7505 - 7509, 2019/12
Times Cited Count:4 Percentile:27.98(Chemistry, Physical)Characterization of the dynamics of disordered polypeptide chains is required to elucidate the behavior of intrinsically disordered proteins and proteins under non-native states related to the folding process. Here we develop a method using quasielastic neutron scattering, combined with small-angle X-ray scattering and dynamic light scattering, to evaluate segmental motions of proteins as well as diffusion of the entire molecules and local side-chain motions. We apply this method to RNase A under the unfolded and molten-globule (MG) states. The diffusion coefficients arising from the segmental motions are evaluated and found to be different between the unfolded and MG states. The values obtained here are consistent with those obtained using the fluorescence-based techniques. These results demonstrate not only feasibility of this method but also usefulness to characterize the behavior of proteins under various disordered states.
Fujiwara, Satoru*; Kono, Fumiaki*; Matsuo, Tatsuhito*; Sugimoto, Yasunobu*; Matsumoto, Tomoharu*; Narita, Tetsuhiro*; Shibata, Kaoru
Journal of Molecular Biology, 431(17), p.3229 - 3245, 2019/08
Times Cited Count:8 Percentile:43.43(Biochemistry & Molecular Biology)-synuclein (
Syn) is an intrinsically disordered protein (IDP) with unknown function.
Syn is known to form amyloid fibrils, which are implicated with the pathogenesis of Parkinson's disease and other synucleinopathies. Elucidating the mechanism of fibril formation of
Syn is therefore important for understanding the mechanism of the pathogenesis of these diseases. Here, using the quasielastic neutron scattering (QENS) and small-angle X-ray scattering (SAXS) techniques, we investigated the dynamic and structural properties of
Syn. These results imply that fibril formation of
Syn requires not only the enhanced local motions but also the segmental motions such that the proper inter-molecular interactions are possible.
Aratani, Hidekazu*; Nakatani, Yasuhiro*; Fujiwara, Hidenori*; Kawada, Moeki*; Kanai, Yuina*; Yamagami, Kohei*; Fujioka, Shuhei*; Hamamoto, Satoru*; Kuga, Kentaro*; Kiss, Takayuki*; et al.
Physical Review B, 98(12), p.121113_1 - 121113_6, 2018/09
Times Cited Count:3 Percentile:18.48(Materials Science, Multidisciplinary)Matsuo, Tatsuhito; Arata, Toshiaki*; Oda, Toshiro*; Nakajima, Kenji; Kawamura, Seiko; Kikuchi, Tatsuya; Fujiwara, Satoru
Biochemistry and Biophysics Reports (Internet), 6, p.220 - 225, 2016/07
Fujiwara, Satoru; Araki, Katsuya*; Matsuo, Tatsuhito; Yagi, Hisashi*; Yamada, Takeshi*; Shibata, Kaoru; Mochizuki, Hideki*
PLOS ONE (Internet), 11(4), p.e0151447_1 - e0151447_17, 2016/04
Times Cited Count:24 Percentile:69.98(Multidisciplinary Sciences)Chatake, Toshiyuki*; Fujiwara, Satoru
Acta Crystallographica Section D; Structural Biology (Internet), 72(1), p.71 - 82, 2016/01
Times Cited Count:4 Percentile:34.34(Biochemical Research Methods)Matsuo, Tatsuhito; Takeda, Soichi*; Oda, Toshiro*; Fujiwara, Satoru
Biophysics and Physicobiology (Internet), 12, p.145 - 158, 2015/12
Matsuo, Tatsuhito; Arata, Toshiaki*; Oda, Toshiro*; Nakajima, Kenji; Kawamura, Seiko; Kikuchi, Tatsuya; Fujiwara, Satoru
Biochemical and Biophysical Research Communications, 459(3), p.493 - 497, 2015/04
Times Cited Count:4 Percentile:14.35(Biochemistry & Molecular Biology)Tashiro, Koji*; Hanesaka, Makoto*; Yamamoto, Hiroko*; Wasanasuk, K.*; Jayaratri, P.*; Yoshizawa, Yoshinori*; Tanaka, Ichiro*; Niimura, Nobuo*; Kusaka, Katsuhiro*; Hosoya, Takaaki*; et al.
Kobunshi Rombunshu, 71(11), p.508 - 526, 2014/11
Times Cited Count:6 Percentile:20.32(Polymer Science)The crystal structure analysis of various polymer substances has been reviewed on the basis of wide-angle high-energy X-ray and neutron diffraction data. The progress in structural analytical techniques of polymer crystals have been reviewed at first. The structural models proposed so far were reinvestigated and new models have been proposed for various kinds of polymer crystals including polyethylene, poly(vinyl alcohol), poly(lactic acid) and its stereocomplex etc. The hydrogen atomic positions were also clarified by the quantitative analysis of wide-angle neutron diffraction data, from which the physical properties of polymer crystals have been evaluated theoretically. The bonded electron density distribution has been estimated for a polydiacetylene single crystal on the basis of the so-called X-N method or by the combination of structural information derived from X-ray and neutron diffraction data analysis. Some comments have been added about future developments in the field of structure-property relationship determination.
Matsuo, Tatsuhito; Arata, Toshiaki*; Oda, Toshiro*; Fujiwara, Satoru
Biophysics, 9, p.99 - 106, 2013/07
Fujiwara, Satoru; Plazanet, M.*; Oda, Toshiro*
Biochemical and Biophysical Research Communications, 431(3), p.542 - 546, 2013/02
Times Cited Count:4 Percentile:12.05(Biochemistry & Molecular Biology)Fujiwara, Satoru; Nakagawa, Hiroshi
Hamon, 23(1), p.72 - 80, 2013/02
no abstracts in English
Matsuo, Tatsuhito; Natali, F.*; Plazanet, M.*; Zaccai, G.*; Fujiwara, Satoru
Journal of the Physical Society of Japan, 82(Suppl.A), p.SA020_1 - SA020_5, 2013/01
Times Cited Count:3 Percentile:28.33(Physics, Multidisciplinary)Troponin is a protein that regulates the muscle contraction depending on the intracellular Ca concentration. K247R mutation of TnT is known to cause the hypertrophic cardiomyopathy. In this work, neutron scattering was used to detect possible changes in dynamics of troponin caused by mutation. Elastic incoherent neutron scattering experiments were carried out on solution samples of the wild type, and K247R mutant at the IN13 spectrometer at the Institut Laue-Langevin, at temperatures between 280 K and 292 K with an interval of 3 K. From the measured scattering data, force constants (
k
), which reflect the resilience of the protein, were calculated. The
k
values for the wild type and K247R mutant were 0.077 (0.035) N/m and 0.046 (0.026) N/m (mean(s.d.)), respectively. This suggests that the disease-causing mutant is more flexible than the wild type. The large flexibility might modulate Ca
signal transmission mechanism, leading to the functional aberration.
Nakagawa, Hiroshi; Fujiwara, Satoru
Hamon, 22(3), p.268 - 273, 2012/08
Takahashi, Nobuaki; Shibata, Kaoru; Kawakita, Yukinobu; Nakajima, Kenji; Inamura, Yasuhiro; Nakatani, Takeshi; Nakagawa, Hiroshi; Fujiwara, Satoru; Sato, Taku*; Tsukushi, Itaru*; et al.
Journal of the Physical Society of Japan, 80(Suppl.B), p.SB007_1 - SB007_4, 2011/12
Times Cited Count:6 Percentile:44.46(Physics, Multidisciplinary)Adare, A.*; Afanasiev, S.*; Aidala, C.*; Ajitanand, N. N.*; Akiba, Y.*; Al-Bataineh, H.*; Alexander, J.*; Aoki, K.*; Aphecetche, L.*; Armendariz, R.*; et al.
Physical Review D, 84(1), p.012006_1 - 012006_18, 2011/07
Times Cited Count:26 Percentile:70.48(Astronomy & Astrophysics)We report on the event structure and double helicity asymmetry () of jet production in longitudinally polarized
collisions at
= 200 GeV. Photons and charged particles were measured by the PHENIX experiment. Event structure was compared with the results from PYTHIA event generator. The production rate of reconstructed jets is satisfactorily reproduced with the next-to-leading-order perturbative QCD calculation. We measured
= -0.0014
0.0037 at the lowest
bin and -0.0181
0.0282 at the highest
bin. The measured
is compared with the predictions that assume various
distributions.
Adare, A.*; Afanasiev, S.*; Aidala, C.*; Ajitanand, N. N.*; Akiba, Yasuyuki*; Al-Bataineh, H.*; Alexander, J.*; Aoki, Kazuya*; Aphecetche, L.*; Armendariz, R.*; et al.
Physical Review C, 83(6), p.064903_1 - 064903_29, 2011/06
Times Cited Count:169 Percentile:99.44(Physics, Nuclear)Transverse momentum distributions and yields for , and
in
collisions at
= 200 and 62.4 GeV at midrapidity are measured by the PHENIX experiment at the RHIC. We present the inverse slope parameter, mean transverse momentum, and yield per unit rapidity at each energy, and compare them to other measurements at different
collisions. We also present the scaling properties such as
and
scaling and discuss the mechanism of the particle production in
collisions. The measured spectra are compared to next-to-leading order perturbative QCD calculations.
Fujiwara, Satoru
Seibutsu Butsuri, 51(3), p.138 - 139, 2011/06
no abstracts in English