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Search Results: Records 1-20 displayed on this page of 59

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Journal Articles

ARKADIA; For the innovation of advanced nuclear reactor design

Ohshima, Hiroyuki; Asayama, Tai; Furukawa, Tomohiro; Tanaka, Masaaki; Uchibori, Akihiro; Takata, Takashi; Seki, Akiyuki; Enuma, Yasuhiro

Journal of Nuclear Engineering and Radiation Science, 9(2), p.025001_1 - 025001_12, 2023/04

https://doi.org/10.1115/1.4054726

This paper describes the outline and development plan for ARKADIA to transform advanced nuclear reactor design to meet expectations of a safe, economic, and sustainable carbon-free energy source. ARKADIA will realize Artificial Intelligence (AI)-aided integrated numerical analysis to offer the best possible solutions for the design and operation of a nuclear plant, including optimization of safety equipment. State-of-the-art numerical simulation technologies and a knowledge base that stores data and insights from past nuclear reactor development projects and R&D are integrated with AI. In the first phase of development, ARKADIA-Design and ARKADIA-Safety will be constructed individually, with the first target of sodium-cooled reactor. In a subsequent phase, everything will be integrated into a single entity applicable not only to advanced rectors with a variety of concepts, coolants, configurations, and output levels but also to existing light-water reactors.

Journal Articles

Study on reactor vessel coolability of sodium-cooled fast reactor under severe accident condition; Water experiments using a scale model

Ono, Ayako; Kurihara, Akikazu; Tanaka, Masaaki; Ohshima, Hiroyuki; Kamide, Hideki; Miyake, Yasuhiro*; Ito, Masami*; Nakane, Shigeru*

Proceedings of 2017 International Congress on Advances in Nuclear Power Plants (ICAPP 2017) (CD-ROM), 10 Pages, 2017/04

The water experiment apparatus simulating the thermal hydraulics in a reactor vessel under operating the decay heat removal systems (DHRSs) was fabricated. The theoretical evaluation for similarity and results of basic experiments show applicability for a scale model experiment of a sodium-cooled fast reactor. This paper, moreover, describes the results of flow visualization experiment under operating a dipped-type passive DHX, which is planned to be installed in both a loop type reactor and pool type reactor, and the calculation results using FLUENT comparing with the result of water experiment.

Journal Articles

Medical application of radiohalogenated peptides; Synthesis and ${it in vitro}$ evaluation of F(${it p}$-$$^{131}$$I)KCCYSL for targeting HER2

Sasaki, Ichiro; Watanabe, Shigeki; Ohshima, Yasuhiro; Sugo, Yumi; Yamada, Keiichi*; Hanaoka, Hirofumi*; Ishioka, Noriko

Peptide Science 2015, p.243 - 246, 2016/03

Journal Articles

Development of a widely usable amino acid tracer; $$^{76}$$Br-$$alpha$$-methyl-phenylalanine for tumor PET imaging

Hanaoka, Hirofumi*; Ohshima, Yasuhiro; Suzuki, Yurika*; Yamaguchi, Aiko*; Watanabe, Shigeki; Uehara, Tomoya*; Nagamori, Shushi*; Kanai, Yoshikatsu*; Ishioka, Noriko; Tsushima, Yoshito*; et al.

Journal of Nuclear Medicine, 56(5), p.791 - 797, 2015/05

https://doi.org/10.2967/jnumed.114.152215
 Times Cited Count：16 Percentile：62.22(Radiology, Nuclear Medicine & Medical Imaging)

Journal Articles

Synthesis and ${{it in vitro}}$ evaluation of $$^{64}$$Cu-labeled peptide for tumor imaging

Sugo, Yumi; Sasaki, Ichiro; Watanabe, Shigeki; Ohshima, Yasuhiro; Ishioka, Noriko

JAEA-Review 2014-050, JAEA Takasaki Annual Report 2013, P. 100, 2015/03

https://doi.org/10.11484/jaea-review-2014-050

Journal Articles

${{it In vitro}}$ studies on cellular binding and stability of $$^{64}$$Cu-labeled peptide for tumor imaging

Sugo, Yumi; Ohshima, Yasuhiro; Sasaki, Ichiro; Ishioka, Noriko

Peptide Science 2014, p.303 - 306, 2015/03

Journal Articles

Exploring of peptides with affinity to HER2 from random peptide libraries using radioisotope; Random hexapeptide libraries with fixed amino acid sequence at 1 and 2 positions

Sasaki, Ichiro; Hanaoka, Hirofumi*; Yamada, Keiichi*; Watanabe, Shigeki; Sugo, Yumi; Ohshima, Yasuhiro; Suzuki, Hiroyuki; Ishioka, Noriko

Peptide Science 2014, p.257 - 260, 2015/03

Journal Articles

Development of a novel PET agent using D-amino acid

Ohshima, Yasuhiro; Tsushima, Yoshito*

Hoshasen To Sangyo, (136), p.9 - 12, 2014/06

http://ci.nii.ac.jp/naid/40020125201

no abstracts in English

Journal Articles

Prognostic significance of amino-acid transporter expression (LAT1, ASCT2, and xCT) in surgically resected tongue cancer

Toyoda, Minoru*; Kaira, Kyoichi*; Ohshima, Yasuhiro; Ishioka, Noriko; Shino, Masato*; Sakakura, Koichi*; Takayasu, Yukihiro*; Takahashi, Katsumasa*; Tominaga, Hideyuki*; Oriuchi, Noboru*; et al.

British Journal of Cancer, 110(10), p.2506 - 2513, 2014/05

https://doi.org/10.1038/bjc.2014.178
 Times Cited Count：94 Percentile：95(Oncology)

Journal Articles

Biological significance of fluorine-18-$$alpha$$-methyltyrosine (FAMT) uptake on PET in patients with oesophageal cancer

Suzuki, Shigemasa*; Kaira, Kyoichi*; Ohshima, Yasuhiro; Ishioka, Noriko; Soda, Makoto*; Yokobori, Takehiko*; Miyazaki, Tatsuya*; Oriuchi, Noboru*; Tominaga, Hideyuki*; Kanai, Yoshikatsu*; et al.

British Journal of Cancer, 110(8), p.1985 - 1991, 2014/04

https://doi.org/10.1038/bjc.2014.142
 Times Cited Count：22 Percentile：58.55(Oncology)

Journal Articles

Synthesis and ${it in vitro}$ Evaluation of $$^{64}$$Cu-labeled peptide for tumor imaging

Sugo, Yumi; Sasaki, Ichiro; Watanabe, Shigeki; Ohshima, Yasuhiro; Ishioka, Noriko

Peptide Science 2013, p.355 - 358, 2014/03

Journal Articles

Clinical significance of L-type amino acid transporter 1 expression as a prognostic marker and potential of new targeting therapy in biliary tract cancer

Kaira, Kyoichi*; Sunose, Yutaka*; Ohshima, Yasuhiro; Ishioka, Noriko; Arakawa, Kazuhisa*; Ogawa, Tetsushi*; Sunaga, Noriaki*; Shimizu, Kimihiro*; Tominaga, Hideyuki*; Oriuchi, Noboru*; et al.

BMC Cancer, 13, p.482_1 - 482_12, 2013/10

https://doi.org/10.1186/1471-2407-13-482
 Times Cited Count：61 Percentile：87.01(Oncology)

Journal Articles

Biological evaluation of 3-[$$^{18}$$F]fluoro-$$alpha$$-methyl-D-tyrosine (D-[$$^{18}$$F]FAMT) as a novel amino acid tracer for positron emission tomography

Ohshima, Yasuhiro; Hanaoka, Hirofumi*; Tominaga, Hideyuki*; Kanai, Yoshikatsu*; Kaira, Kyoichi*; Yamaguchi, Aiko*; Nagamori, Shushi*; Oriuchi, Noboru*; Tsushima, Yoshito*; Endo, Keigo*; et al.

Annals of Nuclear Medicine, 27(4), p.314 - 324, 2013/05

https://doi.org/10.1007/s12149-013-0687-7
 Times Cited Count：14 Percentile：50.17(Radiology, Nuclear Medicine & Medical Imaging)

Journal Articles

Synthesis of radioiodinated antitumor cyclic peptide, [$$^{125}$$I]-sansalvamide A derivative

Watanabe, Shigeki; Yamada, Keiichi*; Tsukui, Narutaka*; Hanaoka, Hirofumi*; Ohshima, Yasuhiro; Yamaguchi, Aiko*; Oku, Hiroyuki*; Ishioka, Noriko

JAEA-Review 2012-046, JAEA Takasaki Annual Report 2011, P. 88, 2013/01

https://jopss.jaea.go.jp/pdfdata/JAEA-Review-2012-046.pdf

Journal Articles

Development of a $$^{76}$$Br-labeled amino acid derivative for PET imaging of tumor

Hanaoka, Hirofumi*; Watanabe, Shigeki; Tominaga, Hideyuki*; Ohshima, Yasuhiro; Watanabe, Satoshi; Yamada, Keiichi*; Iida, Yasuhiko*; Ishioka, Noriko; Endo, Keigo*

JAEA-Review 2012-046, JAEA Takasaki Annual Report 2011, P. 89, 2013/01

https://jopss.jaea.go.jp/pdfdata/JAEA-Review-2012-046.pdf

no abstracts in English

Journal Articles

Involvement of Connexin43 hemichannel in ATP release after $$gamma$$-irradiation

Ohshima, Yasuhiro; Tsukimoto, Mitsutoshi*; Harada, Hitoshi*; Kojima, Shuji*

Journal of Radiation Research, 53(4), p.551 - 557, 2012/07

https://doi.org/10.1093/jrr/rrs014
 Times Cited Count：41 Percentile：83.48(Biology)

Journal Articles

Predicting cetuximab accumulation in ${it KRAS}$ wild-type and ${it KRAS}$ mutant colorectal cancer using $$^{64}$$Cu-labeled cetuximab positron emission tomography

Achmad, A.*; Hanaoka, Hirofumi*; Yoshioka, Hiroki*; Yamamoto, Shinji*; Tominaga, Hideyuki*; Araki, Takuya*; Ohshima, Yasuhiro; Oriuchi, Noboru*; Endo, Keigo*

Cancer Science, 103(3), p.600 - 605, 2012/03

https://doi.org/10.1111/j.1349-7006.2011.02166.x
 Times Cited Count：25 Percentile：58.15(Oncology)

Journal Articles

Preparation and biological evaluation of 3-[$$^{76}$$Br]bromo-$$alpha$$-methyl-L-tyrosine, a novel tyrosine analog for PET imaging of tumors

Ohshima, Yasuhiro; Hanaoka, Hirofumi*; Watanabe, Shigeki; Sugo, Yumi; Watanabe, Satoshi; Tominaga, Hideyuki*; Oriuchi, Noboru*; Endo, Keigo*; Ishioka, Noriko

JAEA-Review 2011-043, JAEA Takasaki Annual Report 2010, P. 91, 2012/01

https://jopss.jaea.go.jp/pdfdata/JAEA-Review-2011-043.pdf

Journal Articles

Induction of extracellular ATP mediates increase in intracellular thioredoxin in RAW264.7 cells exposed to low-dose $$gamma$$-rays

Ohshima, Yasuhiro; Kitami, Akihiro*; Kawano, Ayumi*; Tsukimoto, Mitsutoshi*; Kojima, Shuji*

Free Radical Biology & Medicine, 51(6), p.1240 - 1248, 2011/09

https://doi.org/10.1016/j.freeradbiomed.2011.06.014
 Times Cited Count：20 Percentile：48.02(Biochemistry & Molecular Biology)

Journal Articles

Preparation and biological evaluation of 3-[$$^{76}$$Br]bromo-$$alpha$$-methyl-L-tyrosine, a novel tyrosine analog for positron emission tomography imaging of tumors

Ohshima, Yasuhiro; Hanaoka, Hirofumi*; Watanabe, Shigeki; Sugo, Yumi; Watanabe, Satoshi; Tominaga, Hideyuki*; Oriuchi, Noboru*; Endo, Keigo*; Ishioka, Noriko

Nuclear Medicine and Biology, 38(6), p.857 - 865, 2011/08

https://doi.org/10.1016/j.nucmedbio.2011.02.001
 Times Cited Count：14 Percentile：48.8(Radiology, Nuclear Medicine & Medical Imaging)

59 (Records 1-20 displayed on this page)