Initialising ...
Initialising ...
Initialising ...
Initialising ...
Initialising ...
Initialising ...
Initialising ...
Fukui, Roman*; Saga, Ryo*; Matsuya, Yusuke; Tomita, Kazuo*; Kuwahara, Yoshikazu*; Ouchi, Kentaro*; Sato, Tomoaki*; Okumura, Kazuhiko*; Date, Hiroyuki*; Fukumoto, Manabu*; et al.
Scientific Reports (Internet), 12(1), p.1056_1 - 1056_12, 2022/01
Times Cited Count：10 Percentile：91.34(Multidisciplinary Sciences)Alive cancer cells after fractionated irradiations with 2 Gy X-rays per day for more than 30 days show clinically relevant radioresistant. Such radioresistance is experimentally interpreted to attributed to the increment of stem-like cell content. However, only an experimental approach cannot clarify the cell responses (DNA damage and cell death induction) of cancer stem cells, so the radioresistant mechanisms remain uncertain. In addition to the conventional cell experiments using radio-resistant cell lines established after fractionated irradiations, in this study we developed a mathematical model (so called integrated microdosimetric-kinetic (IMK) model) explicitly considering cancer stem-like cell content and DNA damage responses and investigated radioresistant mechanisms acquired after fractionated irradiations. The IMK model analysis suggested that the changes of stem-like cell fraction and DNA repair efficiency play important roles of radioresisitance acquired after irradiations. Considering these into the IMK model, we successfully reproduced the experimental survival of various cell lines and various irradiation conditions. This work would contribute to not only the precise understanding of the radioresistant mechanisms induced after irradiation but also predicting curative effects with high precision.
Okumura, Takuma*; Azuma, Toshiyuki*; Bennet, D. A.*; Caradonna, P.*; Chiu, I.-H.*; Doriese, W. B.*; Durkin, M. S.*; Fowler, J. W.*; Gard, J. D.*; Hashimoto, Tadashi; et al.
IEEE Transactions on Applied Superconductivity, 31(5), p.2101704_1 - 2101704_4, 2021/08
Times Cited Count：1 Percentile：11.15(Engineering, Electrical & Electronic)A superconducting transition-edge sensor (TES) microcalorimeter is an ideal X-ray detector for experiments at accelerator facilities because of good energy resolution and high efficiency. To study the performance of the TES detector with a high-intensity pulsed charged-particle beam, we measured X-ray spectra with a pulsed muon beam at the Japan Proton Accelerator Research Complex (J-PARC) in Japan. We found substantial temporal shifts of the X-ray energy correlated with the arrival time of the pulsed muon beam, which was reasonably explained by pulse pileup due to the incidence of energetic particles from the initial pulsed beam.
X raysOkumura, Takuma*; Azuma, Toshiyuki*; Bennet, D. A.*; Caradonna, P.*; Chiu, I. H.*; Doriese, W. B.*; Durkin, M. S.*; Fowler, J. W.*; Gard, J. D.*; Hashimoto, Tadashi; et al.
Physical Review Letters, 127(5), p.053001_1 - 053001_7, 2021/07
Times Cited Count：13 Percentile：79.44(Physics, Multidisciplinary)We observed electronic X rays emitted from muonic iron atoms using a superconducting transition-edge-type sensor microcalorimeter. The energy resolution of 5.2 eV in FWHM allowed us to observe the asymmetric broad profile of the electronic characteristic 
and 
X rays together with the hypersatellite X rays around 6 keV. This signature reflects the time-dependent screening of the nuclear charge by the negative muon and the 
-shell electrons, accompanied by electron side-feeding. Assisted by a simulation, this data clearly reveals the electronic - and -shell hole production and their temporal evolution during the muon cascade process.
Iwamura, Takamichi; Okubo, Tsutomu; Akie, Hiroshi; Kugo, Teruhiko; Yonomoto, Taisuke; Kureta, Masatoshi; Ishikawa, Nobuyuki; Nagaya, Yasunobu; Araya, Fumimasa; Okajima, Shigeaki; et al.
JAERI-Research 2004-008, 383 Pages, 2004/06
JAERI-Research-2004-008.pdf:21.49MB
The present report contains the achievement of "Research and Development on Reduced-Moderation Light Water Reactor with Passive Safety Features", which was performed by Japan Atomic Energy Research Institute (JAERI), Hitachi Ltd., Japan Atomic Power Company and Tokyo Institute of Technology in FY2000-2002 as the innovative and viable nuclear energy technology (IVNET) development project operated by the Institute of Applied Energy (IAE). In the present project, the reduced-moderation water reactor (RMWR) has been developed to ensure sustainable energy supply and to solve the recent problems of nuclear power and nuclear fuel cycle, such as economical competitiveness, effective use of plutonium and reduction of spent fuel storage. The RMWR can attain the favorable characteristics such as high burnup, long operation cycle, multiple recycling of plutonium (Pu) and effective utilization of uranium resources based on accumulated LWR technologies.
Kuriyama, Masaaki; Akino, Noboru; Ebisawa, Noboru; Grisham, L. R.*; Honda, Atsushi; Ito, Takao; Kawai, Mikito; Kazawa, Minoru; Mogaki, Kazuhiko; Ohara, Yoshihiro; et al.
Fusion Science and Technology (JT-60 Special Issue), 42(2-3), p.410 - 423, 2002/09
Times Cited Count：49 Percentile：93.12(Nuclear Science & Technology)no abstracts in English
Kawai, Mikito; Akino, Noboru; Ebisawa, Noboru; Honda, Atsushi; Ito, Takao; Kazawa, Minoru; Kuriyama, Masaaki; Mogaki, Kazuhiko; Oga, Tokumichi; Ohara, Hiroshi; et al.
JAERI-Tech 2001-073, 98 Pages, 2001/11
JAERI-Tech-2001-073.pdf:4.65MB
The world's first negative-ion based neutral beam injector(N-NBI) system has been developed for studies of non-inductive current drive and plasma core heating with high energy neutral beam injection in higher density plasma. Construction of the N-NBI system for JT-60U was completed in March 1996. The system is composed of a beamline with two ion souces, a set of ion source power supllies, control system and auxiliary sub-system such as cooling water, refrigeration and vaccum system. In July 2001, deuterium neutral beam injection of 400keV and 5.8MW into JT-60U plasma was achieved. In order to increase both beam power and energy we have to go on more improvement of the N-NBI.
Ito, Takao; Akino, Noboru; Ebisawa, Noboru; Grisham, L. R.*; Honda, Atsushi; Hu, L.*; Kawai, Mikito; Kazawa, Minoru; Kuriyama, Masaaki; Kusaka, Makoto*; et al.
Fusion Engineering and Design, 51-52, p.1039 - 1047, 2000/11
Times Cited Count：15 Percentile：68.65(Nuclear Science & Technology)no abstracts in English
Kawai, Mikito; Grisham, L. R.*; Ito, Takao; Kazawa, Minoru; Kuriyama, Masaaki; Mogaki, Kazuhiko; Okumura, Yoshikazu; Watanabe, Kazuhiro
Review of Scientific Instruments, 71(2), p.755 - 757, 2000/02
Times Cited Count：10 Percentile：55.17(Instruments & Instrumentation)no abstracts in English
Kuriyama, Masaaki; Akino, Noboru; Ebisawa, Noboru; Grisham, L. R.*; Hikida, Shigenori*; Honda, Atsushi; Ito, Takao; Kawai, Mikito; Kazawa, Minoru; Kusaka, Makoto*; et al.
Review of Scientific Instruments, 71(2), p.751 - 754, 2000/02
Times Cited Count：21 Percentile：72.69(Instruments & Instrumentation)no abstracts in English
Hu, L.*; Akino, Noboru; Ebisawa, Noboru; Honda, Atsushi; Ito, Takao; Kawai, Mikito; Kazawa, Minoru; Kuriyama, Masaaki; Kusaka, Makoto*; Mogaki, Kazuhiko; et al.
JAERI-Tech 99-057, 16 Pages, 1999/08
no abstracts in English
Kuriyama, Masaaki; Akino, Noboru; Ebisawa, Noboru; Grisham, L. R.*; Hikida, Shigenori*; Honda, Atsushi; Ito, Takao; Kawai, Mikito; Kazawa, Minoru; Kusaka, Makoto*; et al.
Proceedings of the 18th IEEE/NPSS Symposium on Fusion Engineering (SOFE '99), p.133 - 136, 1999/00
no abstracts in English
Kuriyama, Masaaki; Akino, Noboru; Ebisawa, Noboru; Grisham, L. R.*; Honda, Atsushi; H.Liquen*; Ito, Takao; Kawai, Mikito; Kazawa, Minoru; Mogaki, Kazuhiko; et al.
Journal of Nuclear Science and Technology, 35(11), p.739 - 749, 1998/11
Times Cited Count：39 Percentile：92.5(Nuclear Science & Technology)no abstracts in English
Kuriyama, Masaaki; Akino, Noboru; Ebisawa, Noboru; Grisham, L. R.*; Honda, Atsushi; Ito, Takao; Kawai, Mikito; Kazawa, Minoru; Kusaka, Makoto*; H.Liquen*; et al.
Fusion Technology 1998, 1, p.391 - 394, 1998/00
no abstracts in English
Kuriyama, Masaaki; Akino, Noboru; Ebisawa, Noboru; Grisham, L. R.*; Hanada, Masaya; Honda, Atsushi; Ito, Takao; Kawai, Mikito; Kazawa, Minoru; *; et al.
Proceedings of 17th IEEE/NPSS Symposium Fusion Engineering (SOFE'97), 1, p.405 - 408, 1998/00
no abstracts in English
Watanabe, Kazuhiro; ; Aoyagi, Tetsuo; ; Fujiwara, Yukio; Honda, Atsushi; Inoue, Takashi; Ito, Takao; Kawai, Mikito; Kazawa, Minoru; et al.
Radiation Physics and Chemistry, 49(6), p.631 - 639, 1997/00
Times Cited Count：3 Percentile：30.37(Chemistry, Physical)no abstracts in English
ion source for the neutral beam injector for JT-60UOkumura, Yoshikazu; Fujiwara, Yukio; Honda, Atsushi; Inoue, Takashi; Kuriyama, Masaaki; Miyamoto, Kenji; Miyamoto, Naoki*; Mogaki, Kazuhiko; Nagase, Akihito*; Ohara, Yoshihiro; et al.
Review of Scientific Instruments, 67(3), p.1018 - 1020, 1996/03
Times Cited Count：29 Percentile：86.28(Instruments & Instrumentation)no abstracts in English
Watanabe, Kazuhiro; ; Fujiwara, Yukio; Honda, Atsushi; Inoue, Takashi; Kazawa, Minoru; Kuriyama, Masaaki; Miyamoto, Kenji; Miyamoto, Naoki*; Mogaki, Kazuhiko; et al.
16th IEEE/NPSS Symp. on Fusion Engineering (SOFE '95), 1, p.642 - 645, 1996/00
no abstracts in English
Kuriyama, Masaaki; ; Araki, Masanori; ; Hanada, Masaya; Inoue, Takashi; Kawai, Mikito; Kazawa, Minoru; *; Kunieda, Shunsuke; et al.
Fusion Engineering and Design, 26, p.445 - 453, 1995/00
Times Cited Count：43 Percentile：95.65(Nuclear Science & Technology)no abstracts in English
Kuriyama, Masaaki; ; Araki, Masanori; ; Hanada, Masaya; Inoue, Takashi; Kawai, Mikito; Kazawa, Minoru; *; Kunieda, Shunsuke; et al.
15th IEEE/NPSS Symp. on Fusion Engineering,Vol. 1, 0, p.470 - 473, 1993/00
no abstracts in English
Kuriyama, Masaaki; Ohara, Yoshihiro; ; ; Hanada, Masaya; Inoue, Takashi; *; *; Ito, Takao; Kawai, Mikito; et al.
Fusion Technology 1992, Vol.1, p.564 - 568, 1993/00
no abstracts in English
Ito, Hisayoshi; Oshima, Takeshi; Okumura, Hajime*; Harima, Hiroshi*; Kishida, Shunji*; Hiramoto, Toshiro*; Hirakawa, Kazuhiko*
no journal, ,
In the presentation, we propose the construction of the super energy saving ecosystems using power electronics based on widegap semiconductors, as autonomous distributed infrastructure systems which work even in emergency cases like East Japan great earthquake disaster. This proposal consists of (1) R&D of advanced power electronics using widegap semiconductors like silicon carbide (SiC) and (2) the construction of super low loss energy control and communication systems based on such advanced power electronics. By realizing such super energy saving ecosystems, advanced eco-cities resisting a disaster are expected to be built. The proposed ecosystems are also quite effective for preventing global warming and promoting industrial development.
