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Omichi, Masaaki*; Asano, Atsushi*; Tsukuda, Satoshi*; Takano, Katsuyoshi*; Sugimoto, Masaki; Saeki, Akinori*; Sakamaki, Daisuke*; Onoda, Akira*; Hayashi, Takashi*; Seki, Shu*
Nature Communications (Internet), 5, p.3718_1 - 3718_8, 2014/04
Times Cited Count:36 Percentile:77.16(Multidisciplinary Sciences)Protein nanowires exhibiting specific biological activities hold promise for interacting with living cells and controlling and predicting biological responses such as apoptosis, endocytosis and cell adhesion. Here we report the result of the interaction of a single high-energy charged particle with protein molecules. Degradation of the human serum albumin nanowires was examined using trypsin. The biotinylated human serum albumin nanowires bound avidin, demonstrating the high affinity of the nanowires. Human serum albumin-avidin hybrid nanowires were also fabricated from a solid state mixture and exhibited good mechanical strength. The biotinylated human serum albumin nanowires can be transformed into nanowires exhibiting a biological function such as avidin-biotinyl interactions and peroxidase activity. The present technique is a versatile platform for functionalizing the surface of any protein molecule with an extremely large surface area.
Miyamoto, Yukihiro; Sakamaki, Tsuyoshi*; Maekawa, Osamu*; Nakashima, Hiroshi
JAERI-Tech 2004-054, 72 Pages, 2004/08
A standard is provided for the radiation monitor based on LAN (Local Area Network) and PLC (Programmable Logic Controller) technology at the introduction to the Japan Proton Accelerator Research Complex (J-PARC). The monitor consists of radiation measurement equipments and the central monitoring panel. The formers are installed in the radiation field, and the latter is installed in the control room and composed of PLC, which are connected with LAN. Extension of the existing standard and the conformity to the international standard were thought as important in providing the standard. The standard is expected to improve the compatibility, maintenancability and productivity of the components.
Tsukada, Kazuaki; Toyoshima, Atsushi; Haba, Hiromitsu*; Asai, Masato; Akiyama, Kazuhiko*; Ishii, Yasuo; Tome, Hayato*; Nishinaka, Ichiro; Sato, Tetsuya; Ichikawa, Takatoshi; et al.
no journal, ,
no abstracts in English