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Journal Articles

Advance in integrated modelling towards prediction and control of JT-60SA plasmas

Hayashi, Nobuhiko; Honda, Mitsuru; Shiraishi, Junya; Miyata, Yoshiaki; Wakatsuki, Takuma; Hoshino, Kazuo; Toma, Mitsunori; Suzuki, Takahiro; Urano, Hajime; Shimizu, Katsuhiro; et al.

Europhysics Conference Abstracts (Internet), 39E, p.P5.145_1 - P5.145_4, 2015/06

Journal Articles

Order effect of repair processes to clustered DNA damage

Shiraishi, Iyo; Suzuki, Masao*; Shikazono, Naoya; Fujii, Kentaro; Yokoya, Akinari

Journal of Radiation Research, 55(Suppl.1), p.i92 - i93, 2014/03

Journal Articles

Optimization of JT-60SA plasma operational scenario with capabilities of installed actuators

Ide, Shunsuke; Aiba, Nobuyuki; Bolzonella, T.*; Challis, C. D.*; Fujita, Takaaki; Giruzzi, G.*; Joffrin, E.*; Hamamatsu, Kiyotaka; Hayashi, Nobuhiko; Honda, Mitsuru; et al.

Proceedings of 24th IAEA Fusion Energy Conference (FEC 2012) (CD-ROM), 8 Pages, 2013/03

Journal Articles

Induction of DNA damage, including abasic sites, in plasmid DNA by carbon ion and X-ray irradiation

Shiina, Takuya; Watanabe, Ritsuko; Shiraishi, Iyo; Suzuki, Masao*; Sugaya, Yuki; Fujii, Kentaro; Yokoya, Akinari

Radiation and Environmental Biophysics, 52(1), p.99 - 112, 2013/03

 Times Cited Count:17 Percentile:59.39(Biology)

Journal Articles

Study on corrosion of stainless steel in boiling nitric acid under heat transfer conditions

Ueno, Fumiyoshi; Shiraishi, Hironori; Inoue, Shun; Motooka, Takafumi; Kato, Chiaki; Yamamoto, Masahiro; Uchiyama, Gunzo; Nojima, Yasuo*; Fujine, Sachio*

Proceedings of 20th International Conference on Nuclear Engineering and the ASME 2012 Power Conference (ICONE-20 & POWER 2012) (DVD-ROM), 8 Pages, 2012/07

In PUREX process for spent fuel reprocessing plants, heating portions in the components are severely corroded in the boiling solution under heat transfer (HT) conditions. In this paper, authors have focused on the effects of surface temperature and heat flux on corrosion rates (CRs) of stainless steels in boiling nitric acid under HT conditions. Two types of cells for HT and immersion conditions were applied for corrosion tests. Test solution used was 33 mol/m$$^{3}$$ vanadium added to 3 kmol/m$$^{3}$$ nitric acid solution, and was heated at boiling temperature under atmospheric pressure. Additionally, a boiling curve which was indicated the relation between heat flux and degree of superheating was investigated experimentally. Surface temperatures during corrosion tests were estimated from a boiling curve. The results showed that CR did not depend on heat flux, but depended on surface temperature. Arrhenius plots on CRs indicated that CR was accelerated by solution boiling against non-boiling.

Journal Articles

Free radical scavenger edaravone suppresses X-ray-induced apoptosis through p53 inhibition in MOLT-4 cells

Sasano, Nakashi*; Enomoto, Atsushi*; Hosoi, Yoshio*; Katsumura, Yosuke; Matsumoto, Yoshihisa*; Shiraishi, Kenshiro*; Miyagawa, Kiyoshi*; Igaki, Hiroshi*; Nakagawa, Keiichi*

Journal of Radiation Research, 48(6), p.495 - 503, 2007/11

 Times Cited Count:20 Percentile:52.48(Biology)

JAEA Reports

Statistics of individual doses of JAERI for the past 48 years

Shiraishi, Akemi; Sekiguchi, Masato; Tachibana, Haruo; Yoshizawa, Michio; Komuro, Yuji*; Nemoto, Kiyoko*; Okawa, Ikuko*

JAEA-Data/Code 2006-014, 36 Pages, 2006/06

JAEA-Data-Code-2006-014.pdf:2.46MB

In Japan Atomic Energy Research Institute (JAERI), individual monitoring and dose data recording for radiation workers have been conducted since 1957, the next year of which JAERI was established. This report compiles the statistics of individual doses, such as average doses, collective doses, the number of radiation workers and dose distributions, over the past 48 years from 1957 to 2005, when JAERI merged with Japan Nuclear Cycle Development Institute into Japan Atomic Energy Agency. Transition of the statistics showed the history of radiation works in JAERI and many efforts for dose reduction based on the ALARA principle recommended by ICRP. In addition, it was found from the analysis of cumulative distributions that, in recent years, there was a specific work-group exposed to significantly high dose compared with other workers.

JAEA Reports

The Technological study on the decommissioning of nuclear facility, etc. in the Tokai Research Establishment

Tomii, Hiroyuki; Matsuo, Kiyoshi*; Shiraishi, Kunio; Kato, Rokuro; Watabe, Kozo; Higashiyama, Yutaka; Nagane, Satoru*; Hanawa, Yukimitsu*

JAERI-Tech 2005-017, 65 Pages, 2005/03

JAERI-Tech-2005-017.pdf:3.79MB

no abstracts in English

Journal Articles

Cost estimation method for decommissioning of nuclear facilities

Tomii, Hiroyuki; Matsuo, Kiyoshi*; Shiraishi, Kunio; Watabe, Kozo; Saiki, Hideo*; Kawatsuma, Shinji*; Rindo, Hiroshi*; Zaitsu, Tomohisa*

Dekomisshoningu Giho, (31), p.11 - 20, 2005/03

no abstracts in English

Journal Articles

Cost estimation method for decommissioning of nuclear facilities

Tomii, Hiroyuki*; Matsuo, Kiyoshi*; Shiraishi, Kunio*; Watabe, Kozo*; Saiki, Hideo; Kawatsuma, Shinji; Rindo, Hiroshi; Zaitsu, Tomohisa

Dekomisshoningu Giho, (31), p.11 - 20, 2005/03

Japanese Government decided that Japan Atomic Energy Research Institute ( JAERI ) and Japan Nuclear Cycle Development Institute ( JNC ) shall be consolidated to a New rganization as of October 2005, which organization would be an Institute for comprehensive research and development for atomic.Through the preparation for unification, JAERI and JNC have been developing the Decommissioning program for own facilities, estimating decommissioning cost and the amount of waste from the decommissioning, and developing Management Program. Planning the Decommissioning program, it is important to estimate decommissioning cost effectively, because JAERI and JNC retain about 230 nuclear facilities which are reactors, fuel cycle facilities and research facilities. Then the decommissioning cost estimation method has developed based on several dismantling and replacement experiences. This method has adopted more estimation fomulae for decommissioning various works than ever, so as to be more reliable. And decommissioning cost for the facilities has estimated under the common condition. This method would be improved, reflecting future nuclear facilities dismantling and replacement events.This paper shows the cost estimation method for nuclear facilities and cost evaluation result for about 230 facilities of both JAERI and JNC.

Oral presentation

Statistics of individual doses of JEARI for the past 48 years

Shiraishi, Akemi; Sekiguchi, Masato; Tachibana, Haruo; Yoshizawa, Michio; Komuro, Yuji*; Nemoto, Kiyoko*; Okawa, Ikuko*

no journal, , 

no abstracts in English

Oral presentation

Dependence of the yields of AP sites and AP clusters produced in pUC18 plasmid DNA on scavenging capacity and radiation quality

Shiina, Takuya; Sugaya, Yuki; Shiraishi, Iyo; Watanabe, Ritsuko; Yokoya, Akinari

no journal, , 

Many studies using synthetic AP clusters reported that AP clusters retard base excision repair processes. Sutherland et al. (2002) showed that AP clusters are induced efficiently in human cells by low LET X-irradiation with the similar yields with those for the pyrimidine or purine base lesion clusters. There, however, has been very little knowledge of AP sites and AP clusters induced by high LET radiation. In order to clarify the relation between track structure of C ions or X-rays and the induction processes of an AP or AP clusters, we measure the yield of AP sites visualized by the treatment of irradiated pUC18 plasmid DNA with the AP endoclease (Nfo), which converts an AP site to detectable single strand break. Several scavenging capacities of the samples are tested to estimate the effect of indirect action of diffusible OH radicals. These experimental data will be discussed with theoretical radiation track structure in the respect of repair susceptibility of the AP cluster.

Oral presentation

Induction of DNA strand breaks, base lesions and AP sites in plasmid DNA films by oxygen K-shell resonance excitation

Sugaya, Yuki; Shiraishi, Iyo; Shiina, Takuya; Fujii, Kentaro; Yokoya, Akinari

no journal, , 

no abstracts in English

Oral presentation

Study on ageing behavior of reprocessing plants, 5; Effect of surface temperature and solution boiling on corrosion behavior of stainless steel in nitric acid solution

Ueno, Fumiyoshi; Shiraishi, Hironori; Inoue, Shun; Motooka, Takafumi; Kato, Chiaki; Yamamoto, Masahiro; Uchiyama, Gunzo; Nojima, Yasuo*; Fujine, Sachio*

no journal, , 

Effect of metal surface temperature and solution boiling on corrosion of stainless steel in boiling nitric acid solution at heating portion was studied to investigate ageing behavior of the components in spent fuel reprocessing plant. Corrosion tests under the conditions of heat transfer and immersion in atmospheric pressure were carried out using nitric acid solution including Vanadium. As the results, apparent activation energies of thermal dependences on corrosion rates of both the heat transfer and the immersion were indicated approximately 40 kJ/mol. Corrosion rate under the boiling condition were higher about 7 times for the non-boiling condition.

Oral presentation

Order effect of base excision processes to repair clustered DNA damage

Yokoya, Akinari; Shiraishi, Iyo; Shikazono, Naoya

no journal, , 

In the present study, we investigate how the initial enzymatic repair affects the activity of the latter repair enzyme. Plasmid DNA (pUC18) irradiated with C$$^{6+}$$ ion is treated with two base excision repair enzymes, Nth and Fpg, which convert pyrimidine and purine lesions to a SSB. The enzymatic activities are quantified by measuring the conformational changes of the plasmid using agarose gel electrophoresis. Obtained results show that the amount of enzymatically induced SSB is slightly (about 5%) less in DNA sample treated with Nth first and then Fpg than that in the sample treated with Fpg first and then Nth, or with both enzymes simultaneously. The repairability of clustered damage induced by high-LET ions will be discussed.

Oral presentation

Dependence of the yields of AP sites and AP clusters produced in pUC18 plasmid DNA on scavenging capacity and radiation quality and LET

Shiina, Takuya; Sugaya, Yuki; Shiraishi, Iyo; Watanabe, Ritsuko; Yokoya, Akinari; Tsuruoka, Chizuru*; Suzuki, Masao*

no journal, , 

There has been very little knowledge of AP sites and AP clusters induced by heavy ion beam irradiation. In order to clarify the relation between track structure of C ions (290MeV/nucleon, LET 13, 60keV/$$mu$$m) or X-rays and the induction processes of an AP or AP clusters, we measure the yield of AP sites visualized by the treatment of irradiated pUC18 plasmid DNA with the AP endoclease (Nfo), which converts an AP site to detectable single strand break. Several scavenging capacities of the samples are tested to estimate the effect of indirect action of diffusible OH radicals in the induction of AP site. These experimental data will be discussed with theoretical radiation track structure in the respect of repair susceptibility of the AP cluster.

Oral presentation

Order effect of base excision processes to repair clustered DNA damage, 2

Shiraishi, Iyo; Shiina, Takuya; Sugaya, Yuki; Shikazono, Naoya; Yokoya, Akinari

no journal, , 

Cellular response to cluster DNA damage might depend on the order of repair processes because the configuration of the lesions will be modified by the reaction of the initial repair protein, affecting the DNA-binding or lesion-excision activities of the latter repair protein. In the present study, we investigate how the initial enzymatic repair affects the activity of the latter repair enzyme. Plasmid DNA (pUC18) irradiated with C6+ ion is treated with two base excision repair enzymes, Nth and Fpg, which convert pyrimidine and purine lesions to a SSB. The enzymatic activities are quantified by measuring the conformational changes of the plasmid using agarose gel electrophoresis. Obtained results show that the amount of enzymatically induced SSB is slightly (about 5%) less in DNA sample treated with Nth first and then Fpg than that in the sample treated with Fpg first and then Nth. The repairability of clustered damage induced by high-LET ions will be discussed.

Oral presentation

Variation in DNA damage induced by monochromatic soft X-rays in the energy region of oxygen K-edge

Sugaya, Yuki; Shiina, Takuya; Shiraishi, Iyo; Fujii, Kentaro; Yokoya, Akinari

no journal, , 

In this study, we aim to reveal the role of direct ionization at the energy region of oxygen K-edge in the selective DNA damage. We measure the yields of single strand breaks (SSBs), base lesions, and AP sites produced in thin film of pUC18 plasmid DNA by irradiation of several soft X-rays which excite a1s electron to anti-bonding energy states or a vacuum level. The yields of base lesions and AP sites are determined by post-irradiation-treatment of the DNA with enzymatic probes, which excise (Nth and Fpg for pyrimidine and purine base lesion, respectively, and Nfo for AP site) and convert the lesions into detectable SSBs. The obtained data will be compared with our previous data obtained by soft X-ray irradiation around carbon and nitrogen K-edge region.

Oral presentation

Dependence of the yields of AP clusters produced in plasmid DNA on scavenger capacity and LET

Shiina, Takuya; Sugaya, Yuki; Shiraishi, Iyo; Watanabe, Ritsuko; Suzuki, Masao*; Yokoya, Akinari

no journal, , 

no abstracts in English

Oral presentation

Variation in DNA damage induced by monochromatic soft X-rays in the energy region of oxygen K-edge

Sugaya, Yuki; Shiina, Takuya; Shiraishi, Iyo; Fujii, Kentaro; Yokoya, Akinari

no journal, , 

no abstracts in English

27 (Records 1-20 displayed on this page)