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Mo production in JRR-3Hirose, Akira; Komeda, Masao; Kinase, Masami; Sorita, Takami; Wada, Shigeru
JAEA-Technology 2010-007, 68 Pages, 2010/06
JAEA-Technology-2010-007.pdf:3.76MB
We investigated the production process of Mo, which is parent nuclide of 
Tc, in JRR-3. Tc is most commonly used as a radiopharmaceutical in the field of nuclear medicine. Currently the supplying of Mo is only dependent on imports from foreign countries, so JAEA is aiming at domestic production of a part of Mo in cooperation with the industrial arena. This report presents the technical study for the production process of Mo by using the neutron radiation method of (n,
) reaction in JRR-3.
Ir radiation sources for intravascular irradiationKogure, Hiroto; Sorita, Takami; Iwamoto, Seikichi; Nagata, Yasushi*; Hiraoka, Masahiro*; Iwata, Kazuro*; Kawauchi, Yukimasa*; Suzuki, Kazutoshi*
JAERI-Tech 2003-003, 26 Pages, 2003/03
JAERI-Tech-2003-003.pdf:4.83MB
Intravascular brachytherapy is a novel therapy for preventing the restenosis of coronary artery by use of low-dose irradiation. JAERI and Kyoto University have been developing Ir radiation sources by the cooperative research project entitled as "The research on safety and effectiveness of the intravascular brachytherapy for preventing restenosis of the coronary artery disease" since 1998. The radiation source was introduced into the stenosis through a catheter (a guide-tube to insert directly into vascular) to irradiate the diseased part. Ten Ir seed sources (
0.4 mm 
2.5 mm) were positioned between nylon spacers (0.3 mm 1.0 mm) in a flexible covering tube and the tube was plugged with a core-wire; the tube was shrunk to fix the inside materials and the size is 0.46 mm in diameter and 3 m in length. The physically optimal design was determined to insert the radiation source easily into vascular and to get the dose uniformity in the diseased part. The production method of the radiation source, which is practical to use in the clinics was also established.
Sekine, Toshiaki; Izumo, Mishiroku; Matsuoka, Hiromitsu; Kobayashi, Katsutoshi; ; Osa, Akihiko; Koizumi, Mitsuo; Motoishi, Shoji; Hashimoto, Kazuyuki; ; et al.
Proc. of the 5th Int. Workshop on Targetry and Target Chemistry, 0, p.347 - 352, 1994/00
no abstracts in English
Tc with proton bombardment of 
MoIzumo, Mishiroku; Matsuoka, Hiromitsu; Sorita, Takami; Nagame, Yuichiro; Sekine, Toshiaki; ; *
Applied Radiation and Isotopes, 42(3), p.297 - 301, 1991/00
no abstracts in English
Tc with the Mo(p,n) reactionIzumo, Mishiroku; Sorita, Takami; Matsuoka, Hiromitsu; Nagame, Yuichiro; ; Sekine, Toshiaki;
JAERI-M 90-156, 13 Pages, 1990/09
no abstracts in English
Pu and 
Pu with Np targetsIzumo, Mishiroku; Sorita, Takami; ; Sekine, Toshiaki; Matsuoka, Hiromitsu; Motoki, Ryozo; *
JAERI-M 90-102, 28 Pages, 1990/07
no abstracts in English
Re solutions from alumina-based W/Re generatorHashimoto, Kazuyuki; Motoishi, Shoji; Saeki, Hideya*; Sorita, Takami; Matsuoka, Hiromitsu
no journal, ,
no abstracts in English
Re- and Re-DMSAs and removal of impurity in the productKomoto, Kazuki*; Nogawa, Norio*; Sato, Jun*; Makide, Yoshihiro*; Morikawa, Naotake*; Hashimoto, Kazuyuki; Sorita, Takami
no journal, ,
Complex compound of Re and Re with meso-2,3-dimercaptosuccinic acid (DMSA) is expected to be effective against cancerous disease. This compound is synthesized with high radiochemical yield by use of SnCl
as reducing reagent. However, the product contains a large amount of SnCl which is harmful to human body. The removal of tin impurity was tested with cation exchange resin. Re-DMSA complex was also obtained with high radiochemical yield by use of other harmless reducing agents (L-ascorbic acid, NaSO
, HPO). Synthesized Re-DMSA by use of SnCl was stable in sodium acetate buffer for 5 hours, while survival amount of Re-DMSA synthesized by other reducing agents decreased in a short time.
Re solutions by a multi column system for cancer therapeutic experimentsHashimoto, Kazuyuki; Motoishi, Shoji*; Saeki, Hideya*; Sorita, Takami; Matsuoka, Hiromitsu
no journal, ,
Rhenium-188 is a useful generator-produced radioisotope for therapeutic applications because of their energetic beta particles and rays suitable for imaging. Because the W parent is obtained in a relatively low specific activity from the irradiation of enriched W in a reactor, relatively large volumes of normal saline are required to elute the Re from alumina based W/Re generators. In this study, a simple apparatus for effective concentrations of 188Re solutions from alumina-based W/Re generators was developed by a tandem cation-anion column system. Concentration ratios greater than 50:1 can be achieved with this apparatus.
Hirose, Akira; Komeda, Masao; Kinase, Masami; Sorita, Takami; Sagawa, Hisashi; Wada, Shigeru
no journal, ,
no abstracts in English
Mo amount generated by irradiating natural Mo in JRR-3Komeda, Masao; Hirose, Akira; Sorita, Takami; Wada, Shigeru; Ishikawa, Koji*
no journal, ,
no abstracts in English
