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Toyoda, Minoru*; Kaira, Kyoichi*; Ohshima, Yasuhiro; Ishioka, Noriko; Shino, Masato*; Sakakura, Koichi*; Takayasu, Yukihiro*; Takahashi, Katsumasa*; Tominaga, Hideyuki*; Oriuchi, Noboru*; et al.
British Journal of Cancer, 110(10), p.2506 - 2513, 2014/05
Times Cited Count：113 Percentile：95.20(Oncology)
-methyltyrosine (FAMT) uptake on PET in patients with oesophageal cancerSuzuki, Shigemasa*; Kaira, Kyoichi*; Ohshima, Yasuhiro; Ishioka, Noriko; Soda, Makoto*; Yokobori, Takehiko*; Miyazaki, Tatsuya*; Oriuchi, Noboru*; Tominaga, Hideyuki*; Kanai, Yoshikatsu*; et al.
British Journal of Cancer, 110(8), p.1985 - 1991, 2014/04
Times Cited Count：25 Percentile：59.62(Oncology)Kaira, Kyoichi*; Sunose, Yutaka*; Ohshima, Yasuhiro; Ishioka, Noriko; Arakawa, Kazuhisa*; Ogawa, Tetsushi*; Sunaga, Noriaki*; Shimizu, Kimihiro*; Tominaga, Hideyuki*; Oriuchi, Noboru*; et al.
BMC Cancer, 13, p.482_1 - 482_12, 2013/10
Times Cited Count：82 Percentile：89.60(Oncology)
F]fluoro--methyl-D-tyrosine (D-[F]FAMT) as a novel amino acid tracer for positron emission tomographyOhshima, Yasuhiro; Hanaoka, Hirofumi*; Tominaga, Hideyuki*; Kanai, Yoshikatsu*; Kaira, Kyoichi*; Yamaguchi, Aiko*; Nagamori, Shushi*; Oriuchi, Noboru*; Tsushima, Yoshito*; Endo, Keigo*; et al.
Annals of Nuclear Medicine, 27(4), p.314 - 324, 2013/05
Times Cited Count：17 Percentile：50.38(Radiology, Nuclear Medicine & Medical Imaging)
Br-labeled amino acid derivative for PET imaging of tumorHanaoka, Hirofumi*; Watanabe, Shigeki; Tominaga, Hideyuki*; Ohshima, Yasuhiro; Watanabe, Satoshi; Yamada, Keiichi*; Iida, Yasuhiko*; Ishioka, Noriko; Endo, Keigo*
JAEA-Review 2012-046, JAEA Takasaki Annual Report 2011, P. 89, 2013/01
no abstracts in English
wild-type and mutant colorectal cancer using 
Cu-labeled cetuximab positron emission tomographyAchmad, A.*; Hanaoka, Hirofumi*; Yoshioka, Hiroki*; Yamamoto, Shinji*; Tominaga, Hideyuki*; Araki, Takuya*; Ohshima, Yasuhiro; Oriuchi, Noboru*; Endo, Keigo*
Cancer Science, 103(3), p.600 - 605, 2012/03
Times Cited Count：27 Percentile：57.01(Oncology)Br]bromo--methyl-L-tyrosine, a novel tyrosine analog for PET imaging of tumorsOhshima, Yasuhiro; Hanaoka, Hirofumi*; Watanabe, Shigeki; Sugo, Yumi; Watanabe, Satoshi; Tominaga, Hideyuki*; Oriuchi, Noboru*; Endo, Keigo*; Ishioka, Noriko
JAEA-Review 2011-043, JAEA Takasaki Annual Report 2010, P. 91, 2012/01
Br]bromo--methyl-L-tyrosine, a novel tyrosine analog for positron emission tomography imaging of tumorsOhshima, Yasuhiro; Hanaoka, Hirofumi*; Watanabe, Shigeki; Sugo, Yumi; Watanabe, Satoshi; Tominaga, Hideyuki*; Oriuchi, Noboru*; Endo, Keigo*; Ishioka, Noriko
Nuclear Medicine and Biology, 38(6), p.857 - 865, 2011/08
Times Cited Count：15 Percentile：46.06(Radiology, Nuclear Medicine & Medical Imaging)Cu -labeled trastuzumab PETPaudyal, P.*; Paudyal, B.*; Hanaoka, Hirofumi*; Oriuchi, Noboru*; Iida, Yasuhiko*; Yoshioka, Hiroki*; Tominaga, Hideyuki*; Watanabe, Satoshi; Watanabe, Shigeki; Ishioka, Noriko; et al.
JAEA-Review 2010-065, JAEA Takasaki Annual Report 2009, P. 108, 2011/01
Cu-labeled trastuzumab PETPaudyal, P.*; Paudyal, B.*; Hanaoka, Hirofumi*; Oriuchi, Noboru*; Iida, Yasuhiko*; Yoshioka, Hiroki*; Tominaga, Hideyuki*; Watanabe, Satoshi; Watanabe, Shigeki; Ishioka, Noriko; et al.
Cancer Science, 101(4), p.1045 - 1050, 2010/04
Times Cited Count：40 Percentile：67.06(Oncology)Cu-labeled DOTA-
-Phe
-Tyr
-octreotide (Cu-DOTA-TOC) for imaging somatostatin receptor-expressing tumorsHanaoka, Hirofumi*; Tominaga, Hideyuki*; Yamada, Keiichi*; Paudyal, P.*; Iida, Yasuhiko*; Watanabe, Shigeki; Paudyal, B.*; Higuchi, Tetsuya*; Oriuchi, Noboru*; Endo, Keigo*
Annals of Nuclear Medicine, 23(6), p.559 - 567, 2009/08
Times Cited Count：19 Percentile：49.36(Radiology, Nuclear Medicine & Medical Imaging)Tominaga, Nozomu*; Umeda, Hideyuki*; Maeda, Keiichi*; Nomoto, Kenichi*; Iwamoto, Nobuyuki
Proceedings of the International Astronomical Union, Volume 4, Symposium S255, p.189 - 193, 2008/06
Times Cited Count：1 Percentile：48.33(Astronomy & Astrophysics)The first metal enrichment in the universe was made by supernova (SN) explosions of population (Pop) III stars. The trace remains in abundance patterns of extremely metal-poor (EMP) stars. We investigate the properties of nucleosynthesis in Pop III SNe by means of comparing their yields with the abundance patterns of the EMP stars. We focus on (1) jet-induced SNe with various energy deposition rates [
ergs s
], and (2) SNe of stars with various main-sequence masses (
) and explosion energies [
ergs]. The varieties of Pop III SNe can explain varieties of the EMP stars: (1) higher [C/Fe] for lower [Fe/H] and (2) trends of abundance ratios [X/Fe] against [Fe/H].
Tominaga, Nozomu*; Umeda, Hideyuki*; Maeda, Keiichi*; Iwamoto, Nobuyuki; Nomoto, Kenichi*
AIP Conference Proceedings 1016, p.49 - 54, 2008/05
We investigate hydrodynamical and nucleosynthetic properties of the jet-induced explosion of a population III 40M
star with a two-dimensional special relativistic hydrodynamical code and compare the abundance patterns of the yields with those of the metal-poor stars. We conclude that (1) the ejection of Fe-peak products and the fallback of unprocessed materials can account for the abundance patterns of the extremely metal-poor stars and that (2) the jet-induced explosion with different energy deposition rates can explain the difference of the abundance patterns of the metal-poor stars.
-element-enhanced metal-poor star BS 16934-002Aoki, Wako*; Honda, Satoshi*; Beers, T. C.*; Hidai, Masahide*; Iwamoto, Nobuyuki; Tominaga, Nozomu*; Umeda, Hideyuki*; Nomoto, Kenichi*; Norris, J. E.*; Ryan, S. G.*
Astrophysical Journal, 660(1, Part1), p.747 - 761, 2007/05
Times Cited Count：46 Percentile：71.95(Astronomy & Astrophysics)A detailed elemental abundance analysis has been carried out for the very metal-poor ([Fe/H] = -2.7) star BS 16934-002, which was identified in our previous work as a star exhibiting large overabundances of Mg and Sc. A comparison of the abundance pattern of this star with that of the well-studied metal-poor star HD 122563 indicates excesses of O, Na, Mg, Al, and Sc in BS 16934-002. Of particular interest, no excess of C or N is found in this object, in contrast to CS 22949-037 and CS 29498-043, two previously known carbon-rich, extremely metal-poor stars with excesses of the elements. No established nucleosynthesis model exists that explains the observed abundancepattern. A supernova model, including mixing and fallback, assuming severe mass loss before explosion, is discussed as a candidate progenitor of BS 16934-002.
-ray bursts and extremely metal-poor stars; Black hole-forming supernovae with relativistic jetsTominaga, Nozomu*; Maeda, Keiichi*; Umeda, Hideyuki*; Nomoto, Kenichi*; Tanaka, Masaomi*; Iwamoto, Nobuyuki; Suzuki, Tomoharu*; Mazzali, P. A.*
Astrophysical Journal, 657(2, Part2), p.L77 - L80, 2007/03
Times Cited Count：120 Percentile：91.77(Astronomy & Astrophysics)Long-duration -ray bursts (GRBs) are thought to be connected with luminous and energetic Type Ic supernovae [SNe, called hypernovae (HNe)] resulting from the black-hole (BH) forming collapse of massive stars. For GRBs 060505 and 060614, however, the expected SNe have not been detected. The upper limits to the SN brightness are about 100 times fainter than GRB-associated HNe (GRB-HNe), corresponding to the upper limits to the ejected 
Ni masses of 
Ni)
. SNe with a small amount of Ni ejection are observed as faint Type II SNe. HNe and faint SNe are thought to be responsible for the formaion of extremely metal-poor (EMP) stars. A relativistic jet-induced BH forming explosion of the 40
star is investigated and hydrodynamic and nucleosynthetic models are presented. These models can explain both GRB-HNe and GRBs without bright SNe in a unified manner. We suggest that GRBs without bright SNe are likely to synthesize Ni)
or 
.
conditionsIwamoto, Nobuyuki; Umeda, Hideyuki*; Nomoto, Kenichi*; Tominaga, Nozomu*; Thielemann, F. K.*; Hix, W. R.*
AIP Conference Proceedings 847, p.409 - 411, 2006/07
The observations of metal-poor stars with metallicity [Fe/H] 
have been extensively performed. The abundance patterns of these stars are well explained by supernova models with extensive material mixing and fallback onto the compact remnant. Nevertheless important deficiencies of odd elements (especially Sc and K) are present in most investigations. Recent simulations of core collapse supernovae showed that innermost ejecta undergo large amounts of neutrino flux and neutrino interactions with materials in these ejecta change electron fraction to 
. Nucleosynthesis in the proton-rich environments allows Sc and Zn (which are less produced in normal supernova models) to be enriched. Therefore, it is interesting to investigate the influence of a large variation of on explosive nucleosynthesis. We calculate nucleosynthesis with ranging from 0.48 to 0.58 in complete and incomplete Si burning layers in Pop III supernovae. We discuss the production of some important nuclei and compare the abundance patterns with those in observed extremely metal-poor stars.
Sadakane, Kozo*; Arai, Akira*; Aoki, Wako*; Arimoto, Nobuo*; Hidai, Masahide*; Onishi, Takashi*; Tajitsu, Akito*; Beers, T. C.*; Iwamoto, Nobuyuki; Tominaga, Nozomu*; et al.
Publications of the Astronomical Society of Japan, 58(3), p.595 - 604, 2006/06
Times Cited Count：12 Percentile：33.17(Astronomy & Astrophysics)We report detailed spectroscopic studies performed for the secondary star in the black hole binary (micro-quasar) V4641 Sgr in order to examine its surface chemical composition and to see if its surface shows any signature of pollution by ejecta from a supernova explosion. We obtain abundances of 10 elements and find definite over-abundances of N (by 0.8 dex or more) and Na (by 0.8 dex) in V4641 Sgr. From line-by-line comparisons of eight other elements (C, O, Mg, Al, Si, Ti, Cr, Fe) between V4641 Sgr and the two normal late B-type stars, which have been reported to have solar abundances. An evolutionary model of a massive close binary system has been constructed to explain the abundances observed in V4641 Sgr. The model suggests that the BH forming supernova in this system was a dark one.
Iwamoto, Nobuyuki; Umeda, Hideyuki*; Tominaga, Nozomu*; Nomoto, Kenichi*; Maeda, Keiichi*
Science, 309(5733), p.451 - 453, 2005/07
Times Cited Count：243 Percentile：97.48(Multidisciplinary Sciences)The recent discovery of a hyper-metal-poor (HMP) star, with a metallicity Fe/H smaller than 1/100,000 of the solar ratio, together with one earlier HMP star, has raised a challenging question whether these HMP stars are the actual first-generation, low-mass stars of the universe. We argue that these HMP stars are the second-generation stars formed from gases that were chemically enriched by the first-generation supernovae. The key to this solution is the very unusual abundance patterns of these HMP stars and the similarities and differences between them. We can reproduce these abundance features with core-collapse "faint" supernova models that include extensive matter mixing and fallback during explosions.
F]fluoro--methyl-D-tyrosine as tumor imaging agentsOhshima, Yasuhiro; Hanaoka, Hirofumi*; Tominaga, Hideyuki*; Watanabe, Shigeki; Oriuchi, Noboru*; Endo, Keigo*; Ishioka, Noriko
no journal, ,
no abstracts in English
Cu labeled trastuzumab in Her2/neu overexpressing non-small cell lung cancer xenograftsPaudyal, P.*; Paudyal, B.*; Iida, Yasuhiko*; Hanaoka, Hirofumi*; Watanabe, Satoshi; Ishioka, Noriko; Watanabe, Shigeki; Takayanagi, Megumi*; Yoshioka, Hiroki*; Oriuchi, Noboru*; et al.
no journal, ,
