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Nasu, Takuya*; Fujita, Yoshitaka
Enerugi Rebyu, 42(10), p.15 - 18, 2022/09
no abstracts in English
Fujita, Yoshitaka; Seki, Misaki; Ngo, M. C.*; Do, T. M. D.*; Hu, X.*; Yang, Y.*; Takeuchi, Tomoaki; Nakano, Hiroko; Fujihara, Yasuyuki*; Yoshinaga, Hisao*; et al.
KURNS Progress Report 2021, P. 118, 2022/07
no abstracts in English
Endo, Akira
Isotope News, (781), P. 3, 2022/06
The research reactor JRR-3 at the Nuclear Science Research Institute of Japan Atomic Energy Agency resumed its operation in February 2021 for the first time in 10 years. After commissioning, neutron beam experimental apparatus and irradiation facilities were used from July to November, and the operation in 2021 was completed as planned. During this period, Ir-192 and Au-198 were produced and supplied for therapeutic use, and test irradiation for the production of Mo-99 was performed. This is resumption of radioisotope production using nuclear reactors in Japan, which had stopped after the Great East Japan Earthquake. This article introduces future efforts of radioisotope production for medical applications in JRR-3.
Fujita, Yoshitaka; Seki, Misaki; Sano, Tadafumi*; Fujihara, Yasuyuki*; Suzuki, Tatsuya*; Yoshinaga, Hisao*; Hori, Junichi*; Suematsu, Hisayuki*; Tsuchiya, Kunihiko
Journal of Physics; Conference Series, 2155, p.012018_1 - 012018_6, 2022/01
Technetium-99m (Tc), the daughter nuclide of Molybdenum-99 (
Mo), is the most commonly used radioisotope in radiopharmaceuticals. The research and development (R&D) for the production of
Mo by the neutron activation method ((n,
) method) has been carried out from viewpoints of no-proliferation and nuclear security, etc. Since the specific activity of
Mo produced by the (n,
) method is extremely low, developing Al
O
with a large Mo adsorption capacity is necessary to adapt (n,
)
Mo to the generator. In this study, three kinds of Al
O
specimens with different raw materials were prepared and compared their adaptability to generators by static and dynamic adsorption. MoO
pellet pieces (1.5g) were irradiated with 5 MW for 20 min in the Kyoto University Research Reactor (KUR). Irradiated MoO
pellet pieces were dissolved in 6M-NaOH aq. In dynamic adsorption, 1 g of Al
O
was filled into a PFA tube (
1.59 mm). The
Mo adsorption capacity of Al
O
specimens under dynamic condition was slightly reduced compared to that under static condition. The
Tc elution rate was about 100% at 1.5 mL of milking in dynamic adsorption, while it was around 56-87% in static adsorption. The
Mo/
Tc ratio of dynamic condition was greatly reduced compared to that of static condition. Therefore, the
Tc elution property is greatly affected by the method of adsorbing Mo, e.g., the column shape, the linear flow rate, etc.
Project 6 Meeting Members for Tsukuba International Strategic Zone
JAEA-Review 2021-016, 102 Pages, 2021/11
In December 2011, the Prime Minister designated Tsukuba and some areas in Ibaraki Prefecture as "Comprehensive Special Zones". In the Tsukuba International Strategic Zone, nine advanced research and development (R&D) projects are underway with the goal of promoting industrialization of life innovation and green innovation utilizing the science and technology in Tsukuba. In these projects, the domestic production of medical radioisotope (Technetium-99m, Tc) was certified as a new project in October 2013, and R&D have been performed in collaboration with related organizations with Japan Atomic Energy Agency (JAEA) as the project leader. Japan is the third largest consumer of molybdenum-99 (
Mo) after the United States and Europe, and all
Mo are imported. Supply will be insufficient if overseas reactors are shut down due to trouble or if transportation (air and land transportations) is stopped due to volcanic eruptions and some accidents. Thus, early domestic production of
Mo is strongly required. This project is a technology development aimed at domestic production of
Mo, which is a raw material of
Tc used as a diagnostic agent. This report summarizes the activities carried out in the first and second phase of the domestic production of medical radioisotope (
Tc) (here referred to as the "Project 6") in Tsukuba International Strategic Zone (FY2014-2020).
Fujita, Yoshitaka; Seki, Misaki; Sano, Tadafumi*; Fujihara, Yasuyuki*; Kitagawa, Tomoya*; Matsukura, Minoru*; Hori, Junichi*; Suzuki, Tatsuya*; Tsuchiya, Kunihiko
Journal of Radioanalytical and Nuclear Chemistry, 327(3), p.1355 - 1363, 2021/03
Times Cited Count:1 Percentile:27.15(Chemistry, Analytical)We prepared three types of AlO
with different surface structures and investigated
Mo-adsorption/
Tc-elution properties using [
Mo]MoO
that was irradiated in the Kyoto University Research Reactor. Al
O
adsorbed [
Mo]molybdate ions in solutions at different pH; the lower was the pH, the higher was the Mo-adsorption capacity of Al
O
. The
Tc-elution properties of molybdate ion adsorbed Al
O
were elucidated by flowing saline. Consequently, it was suggested that
Mo-adsorption/desorption properties are affected by the specific surface of Al
O
and
Tc-elution properties are affected by the crystal structure of Al
O
.
Fujita, Yoshitaka; Seki, Misaki; Namekawa, Yoji*; Nishikata, Kaori; Kato, Yoshiaki; Sayato, Natsuki; Tsuchiya, Kunihiko; Sano, Tadafumi*; Fujihara, Yasuyuki*; Hori, Junichi*; et al.
KURNS Progress Report 2019, P. 157, 2020/08
no abstracts in English
Fujita, Yoshitaka; Seki, Misaki; Namekawa, Yoji*; Nishikata, Kaori; Kimura, Akihiro; Shibata, Akira; Sayato, Natsuki; Tsuchiya, Kunihiko; Sano, Tadafumi*; Fujihara, Yasuyuki*; et al.
KURNS Progress Report 2018, P. 155, 2019/08
no abstracts in English
Saptiama, I.*; Kaneti, Y. V.*; Yuliarto, B.*; Kumada, Hiroaki*; Tsuchiya, Kunihiko; Fujita, Yoshitaka; Malgras, V.*; Fukumitsu, Nobuyoshi*; Sakae, Takeji*; Hatano, Kentaro*; et al.
Chemistry; A European Journal, 25(18), p.4843 - 4855, 2019/03
Times Cited Count:14 Percentile:60.07(Chemistry, Multidisciplinary)The effective utilization of various biomolecules for creating a series of mesoporous boehmite (-AlOOH) and gamma-alumina (
-Al
O
) nanosheets with unique hierarchical multilayered structures is demonstrated. The nature and concentration of the biomolecules strongly influence the degree of the crystallinity, the morphology, and the textural properties of the resulting
-AlOOH and
-Al
O
nanosheets, allowing for easy tuning. The hierarchical
-AlOOH and
-Al
O
multilayered nanosheets synthesized by using biomolecules exhibit enhanced crystallinity, improved particle separation, and well-defined multilayered structures compared to those obtained without biomolecules. More impressively, these
-AlOOH and
-Al
O
nanosheets possess high surface areas up to 425 and 371 m
/g, respectively, due to their mesoporous nature and hierarchical multilayered structure. When employed for molybdenum adsorption toward medical radioisotope production, the hierarchical
-Al
O
multilayered nanosheets exhibit Mo adsorption capacities of 33.1
40.8mg-Mo/g.
Fukumitsu, Nobuyoshi*; Yamauchi, Yusuke*; Saptiama, I.*; Ariga, Katsuhiko*; Hatano, Kentaro*; Kumada, Hiroaki*; Fujita, Yoshitaka; Tsuchiya, Kunihiko
Isotope News, (760), p.15 - 18, 2018/12
no abstracts in English
Fujita, Yoshitaka; Nishikata, Kaori; Namekawa, Yoji*; Kimura, Akihiro; Shibata, Akira; Sayato, Natsuki; Tsuchiya, Kunihiko; Sano, Tadafumi*; Fujihara, Yasuyuki*; Zhang, J.*
KURRI Progress Report 2017, P. 126, 2018/08
no abstracts in English
Tanase, Masakazu*; Fujisaki, Saburo*; Ota, Akio*; Shiina, Takayuki*; Yamabayashi, Hisamichi*; Takeuchi, Nobuhiro*; Tsuchiya, Kunihiko; Kimura, Akihiro; Suzuki, Yoshitaka; Ishida, Takuya; et al.
Radioisotopes, 65(5), p.237 - 245, 2016/05
no abstracts in English
Nuclear Technology and Education Center
JAERI-Conf 2004-010, 236 Pages, 2004/06
The FNCA 2002 Workshop on the Utilization of Research Reactors, which is the eleventh workshop on the theme of research reactor utilization, was held in Jakarta and Serpong, Indonesia from January 13 to 17. This workshop was executed based on the agreement in the third Coordinator's Meeting of Forum for Nuclear Cooperation in Asia (FNCA) held in Tokyo, March 2002. The workshop consists of two groups under the theme of the following fields; 1) Tc-99m Generator Technology, 2) Neutron Activation Analysis. The total number of participants for the workshop was 88 people from 8 countries; China, Indonesia, Korea, Malaysia, the Philippines, Thailand, Vietnam and Japan. This report consists of 8 papers from the plenary session, 10 papers for Tc-99m Generator, 10 papers for Neutron Activation Analysis and a summary report.
; ;
Journal of Nuclear Science and Technology, 8(7), p.357 - 362, 1971/07
no abstracts in English
Suematsu, Hisayuki*; Seki, Misaki*; Sato, Soma*; Nanko, Makoto*; Tsuchiya, Kunihiko; Nishikata, Kaori; Suzuki, Tsuneo*; Nakayama, Tadachika*; Niihara, Koichi*
no journal, ,
no abstracts in English
Tsuchiya, Kunihiko; Suzuki, Yoshitaka; Nishikata, Kaori; Shibata, Akira; Nakamura, Natsuki; Tanase, Masakazu*; Shiina, Takayuki*; Ota, Akio*; Kawabata, Masako*; Takeuchi, Nobuhiro*
no journal, ,
no abstracts in English
Tsuchiya, Kunihiko
no journal, ,
no abstracts in English
Tsuchiya, Kunihiko
no journal, ,
no abstracts in English
Seki, Misaki*; Suematsu, Hisayuki*; Nakayama, Tadachika*; Suzuki, Tsuneo*; Niihara, Koichi*; Suzuki, Tatsuya*; Tsuchiya, Kunihiko; Duong Van, D.*
no journal, ,
no abstracts in English
Tsuchiya, Kunihiko
no journal, ,
no abstracts in English