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Journal Articles

Yields of strand breaks and base lesions induced by soft X-rays in plasmid DNA

Yokoya, Akinari; Fujii, Kentaro; Ushigome, Takeshi; Shikazono, Naoya; Urushibara, Ayumi; Watanabe, Ritsuko

Radiation Protection Dosimetry, 122(1-4), p.86 - 88, 2006/12

 Times Cited Count:11 Percentile:61.93(Environmental Sciences)

We have studied yields of DNA damages induced by soft X-rays obtained from a conventional soft X-ray machine in a LET region between $$gamma$$-rays and ultrasoft X-rays. Practically soft X-rays with a broad energy spectrum emitted from a target of heavy metal, such as tungsten, have been widely used not only for radiobiological experiments but also for medical application such as mammography. Radiation weighting factors for these soft X-rays have been assigned to be 1 by ICRP. However, the fraction of a large number of low energy photons in the spectrum (below several tens keV) provided by bremsstrahlung is expected to be more effective for DNA damage induction than $$gamma$$-rays since low energy photo- and Auger electrons predominantly ejected in consequence of a photoelectric effect can produce dense clusters of ionization/excitation on DNA molecules. We have examined the yield of DNA strand breaks induced by white soft X-rays (150 kVp, tungsten target). Yields of base lesions revealed by base excision repair enzymes will be also presented.

Journal Articles

Inactivation action spectra of bacillus subtilis spores with monochromatic soft X-rays(0.1-0.6nm) of synchrotron radiation

*; Hieda, Kotaro*; Usami, Noriko*; Yokoya, Akinari; Kobayashi, Katsumi*

Radiat. Res., 131(1), p.72 - 80, 1992/07

 Times Cited Count:16 Percentile:58.53(Biology)

no abstracts in English

Journal Articles

Time resolved X-ray absorption spectroscopy apparatus using laser plasma as an X-ray source

Yoda, Osamu; Miyashita, Atsumi; *; *; *

Excimer Lasers and Applications III, p.463 - 466, 1991/00

no abstracts in English

Oral presentation

Yields of DNA strand breaks and base lesions induced by oxygen K-shell electron ionization

Sugaya, Yuki*; Fujii, Kentaro; Yokoya, Akinari

no journal, , 

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