SMALL ACIDIC PROTEIN 1 acts with RUB modification components the COP9 signalosome and AXR1 to regulate growth and development of
SMALL ACIDIC PROTEIN 1は、の生長や発生の制御において、RUB修飾因子であるCOP9シグナルソームやAXR1とともに機能する
中曽根 光*; 藤原 正幸*; 深尾 陽一朗*; Biswas, K.; Rahman, A.*; 山田 真紀*; 鳴海 一成; 内宮 博文*; 大野 豊
Nakasone, Akari*; Fujiwara, Masayuki*; Fukao, Yoichiro*; Biswas, K.; Rahman, A.*; Yamada, Maki*; Narumi, Issei; Uchimiya, Hirofumi*; Ono, Yutaka
We demonstrated that SMALL ACIDIC PROTEIN 1 is required for normal plant growth and development, and roots response to IAA or methyl jasmonate in the () mutation background. Deletion analysis and green fluorescent protein (GFP) / glutathione S-transferase (GST) pull-down assays showed that SMAP1 physically interacts with the CONSTITUTIVE PHOTOMORPHOGENIC-9 SIGNALOSOME (CSN) via the SMAP1 F/D-region. The extremely dwarf phenotype of double mutant confirms the functional role of in plant growth and development under limiting CSN functionality. Our findings suggest that SMAP1 is involved in the auxin response and possibly in other cullin-RING ubiquitin ligase (CRL)-regulated signaling processes via its interaction with components associated with related-to-ubiquitin (RUB) modification.